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François Paquet-Durand
François Paquet-Durand
Forschungsinstitut für Augenheilkunde, Universitaet Tuebingen
Verificeret mail på klinikum.uni-tuebingen.de - Startside
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Photoreceptor cell death mechanisms in inherited retinal degeneration
J Sancho-Pelluz, B Arango-Gonzalez, S Kustermann, FJ Romero, ...
Molecular neurobiology 38, 253-269, 2008
3552008
Restoration of cone vision in the CNGA3−/− mouse model of congenital complete lack of cone photoreceptor function
S Michalakis, R Mühlfriedel, N Tanimoto, V Krishnamoorthy, S Koch, ...
Molecular therapy 18 (12), 2057-2063, 2010
2332010
Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration
B Arango-Gonzalez, D Trifunović, A Sahaboglu, K Kranz, S Michalakis, ...
PloS one 9 (11), e112142, 2014
2182014
Spectral domain optical coherence tomography in mouse models of retinal degeneration
G Huber, SC Beck, C Grimm, A Sahaboglu-Tekgoz, F Paquet-Durand, ...
Investigative ophthalmology & visual science 50 (12), 5888-5895, 2009
2142009
Calpain is activated in degenerating photoreceptors in the rd1 mouse
F Paquet‐Durand, S Azadi, SM Hauck, M Ueffing, T van Veen, P Ekström
Journal of neurochemistry 96 (3), 802-814, 2006
1592006
Safety and vision outcomes of subretinal gene therapy targeting cone photoreceptors in achromatopsia: a nonrandomized controlled trial
MD Fischer, S Michalakis, B Wilhelm, D Zobor, R Muehlfriedel, S Kohl, ...
JAMA ophthalmology 138 (6), 643-651, 2020
1572020
Excessive activation of poly (ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse
F Paquet-Durand, J Silva, T Talukdar, LE Johnson, S Azadi, T van Veen, ...
Journal of Neuroscience 27 (38), 10311-10319, 2007
1562007
PKG activity causes photoreceptor cell death in two retinitis pigmentosa models
F Paquet‐Durand, SM Hauck, T Van Veen, M Ueffing, P Ekström
Journal of neurochemistry 108 (3), 796-810, 2009
1492009
Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse
J Sancho-Pelluz, MV Alavi, A Sahaboglu, S Kustermann, P Farinelli, ...
Cell death & disease 1 (2), e24-e24, 2010
1362010
A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa
F Paquet-Durand, S Beck, S Michalakis, T Goldmann, G Huber, ...
Human molecular genetics 20 (5), 941-947, 2011
1292011
CNTF+ BDNF treatment and neuroprotective pathways in the rd1 mouse retina
S Azadi, LE Johnson, F Paquet-Durand, MTR Perez, Y Zhang, ...
Brain research 1129, 116-129, 2007
1272007
Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3)
J Hübener, JJ Weber, C Richter, L Honold, A Weiss, F Murad, P Breuer, ...
Human molecular genetics 22 (3), 508-518, 2013
1212013
Retina in a dish: Cell cultures, retinal explants and animal models for common diseases of the retina
S Schnichels, F Paquet-Durand, M Löscher, T Tsai, J Hurst, SC Joachim, ...
Progress in retinal and eye research 81, 100880, 2021
1182021
Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration
E Vighi, D Trifunović, P Veiga-Crespo, A Rentsch, D Hoffmann, ...
Proceedings of the National Academy of Sciences 115 (13), E2997-E3006, 2018
1112018
Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats
J Kaur, S Mencl, A Sahaboglu, P Farinelli, T van Veen, E Zrenner, ...
PloS one 6 (7), e22181, 2011
1102011
Cellular mechanisms of hereditary photoreceptor degeneration–Focus on cGMP
M Power, S Das, K Schütze, V Marigo, P Ekström, F Paquet-Durand
Progress in Retinal and Eye Research 74, 100772, 2020
1062020
cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function
M Jaumann, J Dettling, M Gubelt, U Zimmermann, A Gerling, ...
Nature medicine 18 (2), 252-259, 2012
1052012
Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina
J Du, WM Cleghorn, L Contreras, K Lindsay, AM Rountree, AO Chertov, ...
Journal of Biological Chemistry 288 (50), 36129-36140, 2013
932013
Neuroprotective strategies for the treatment of inherited photoreceptor degeneration
D Trifunovic, A Sahaboglu, J Kaur, S Mencl, E Zrenner, M Ueffing, ...
Current molecular medicine 12 (5), 598-612, 2012
932012
PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function
A Sahaboglu, N Tanimoto, J Kaur, J Sancho-Pelluz, G Huber, E Fahl, ...
PloS one 5 (11), e15495, 2010
922010
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