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George Dubyak
George Dubyak
Professor of Physiology & Biophysics, Case Western Reserve University
Verificeret mail på case.edu
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Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides
GR Dubyak, C El-Moatassim
American Journal of Physiology-Cell Physiology 265 (3), C577-C606, 1993
15921993
Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes.
M Lam, G Dubyak, L Chen, G Nunez, RL Miesfeld, CW Distelhorst
Proceedings of the National Academy of Sciences 91 (14), 6569-6573, 1994
8951994
Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells.
MS Simonson, S Wann, P Mene, GR Dubyak, M Kester, Y Nakazato, ...
The Journal of clinical investigation 83 (2), 708-712, 1989
7291989
Nonclassical IL-1β secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
Y Qu, L Franchi, G Nunez, GR Dubyak
The Journal of Immunology 179 (3), 1913-1925, 2007
6872007
Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells
MG Strainic, J Liu, D Huang, F An, PN Lalli, N Muqim, VS Shapiro, ...
Immunity 28 (3), 425-435, 2008
6722008
ADP receptors of platelets and their inhibition
C Gachet
Thrombosis and haemostasis 86 (07), 222-232, 2001
5742001
The insulin-mimetic effects of vanadate in isolated rat adipocytes. Dissociation from effects of vanadate as a (Na+-K+) ATPase inhibitor.
GR Dubyak, A Kleinzeller
Journal of Biological Chemistry 255 (11), 5306-5312, 1980
5201980
Towards a revised nomenclature for P1 and P2 receptors
BB Fredholm, MP Abbracchio, G Burnstock, GR Dubyak, TK Harden, ...
Trends in pharmacological sciences 18 (3), 79, 1997
4631997
Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release
JM Kahlenberg, GR Dubyak
American Journal of Physiology-Cell Physiology 286 (5), C1100-C1108, 2004
4572004
Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation
Y Qu, S Misaghi, K Newton, LL Gilmour, S Louie, JE Cupp, GR Dubyak, ...
The Journal of Immunology 186 (11), 6553-6561, 2011
4302011
Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria
L Franchi, TD Kanneganti, GR Dubyak, G Nunez
Journal of Biological Chemistry 282 (26), 18810-18818, 2007
4282007
Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis
JK Rathkey, J Zhao, Z Liu, Y Chen, J Yang, HC Kondolf, BL Benson, ...
Science immunology 3 (26), eaat2738, 2018
4172018
Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP
M Karmakar, MA Katsnelson, GR Dubyak, E Pearlman
Nature communications 7 (1), 10555, 2016
3962016
Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase
R Beigi, E Kobatake, M Aizawa, GR Dubyak
American Journal of Physiology-Cell Physiology 276 (1), C267-C278, 1999
3711999
N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis
M Karmakar, M Minns, EN Greenberg, J Diaz-Aponte, K Pestonjamasp, ...
Nature communications 11 (1), 2212, 2020
3212020
K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling
MA Katsnelson, LG Rucker, HM Russo, GR Dubyak
The Journal of Immunology 194 (8), 3937-3952, 2015
3142015
Intracellular calcium changes trigger connexin 32 hemichannel opening
E De Vuyst, E Decrock, L Cabooter, GR Dubyak, CC Naus, WH Evans, ...
The EMBO journal 25 (1), 34-44, 2006
3002006
Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor
BD Humphreys, J Rice, SB Kertesy, GR Dubyak
Journal of Biological Chemistry 275 (35), 26792-26798, 2000
2922000
Signal transduction by P2-purinergic receptors for extracellular ATP
GR Dubyak
Am J Respir Cell Mol Biol 4 (4), 295-300, 1991
2761991
Cutting edge: the nucleotide receptor P2X7 contains multiple protein-and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide
LC Denlinger, PL Fisette, JA Sommer, JJ Watters, U Prabhu, GR Dubyak, ...
The Journal of Immunology 167 (4), 1871-1876, 2001
2522001
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