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Keld Fosgerau
Keld Fosgerau
CEO, Pephexia Therapeutics
Verificeret mail på pephexia.com - Startside
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Peptide therapeutics: current status and future directions
K Fosgerau, T Hoffmann
Drug discovery today 20 (1), 122-128, 2015
30542015
Mouse models of nonalcoholic steatohepatitis in preclinical drug development
HH Hansen, M Feigh, SS Veidal, KT Rigbolt, N Vrang, K Fosgerau
Drug discovery today 22 (11), 1707-1718, 2017
2442017
Astrocyte glycogen sustains neuronal activity during hypoglycemia: studies with the glycogen phosphorylase inhibitor CP-316,819 ([RR*, S*]-5-chloro-N-[2-hydroxy-3 …
SW Suh, JP Bergher, CM Anderson, JL Treadway, K Fosgerau, ...
Journal of Pharmacology and Experimental Therapeutics 321 (1), 45-50, 2007
2352007
Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter
AM Brown, HM Sickmann, K Fosgerau, TM Lund, A Schousboe, ...
Journal of neuroscience research 79 (1‐2), 74-80, 2005
1982005
Long-term characterization of the diet-induced obese and diet-resistant rat model: a polygenetic rat model mimicking the human obesity syndrome
AN Madsen, G Hansen, SJ Paulsen, K Lykkegaard, M Tang-Christensen, ...
Journal of Endocrinology 206 (3), 287, 2010
1852010
Glucagon receptor knockout mice display increased insulin sensitivity and impaired β-cell function
H Sørensen, MS Winzell, CL Brand, K Fosgerau, RW Gelling, E Nishimura, ...
Diabetes 55 (12), 3463-3469, 2006
1352006
Kinetic and functional characterization of 1, 4-dideoxy-1, 4-imino-d-arabinitol: a potent inhibitor of glycogen phosphorylase with anti-hyperglyceamic effect in ob/ob mice
K Fosgerau, N Westergaard, B Quistorff, N Grunnet, M Kristiansen, ...
Archives of biochemistry and biophysics 380 (2), 274-284, 2000
1292000
Characterisation of age-dependent beta cell dynamics in the male db/db mice
LS Dalbøge, DLC Almholt, TSR Neerup, E Vassiliadis, N Vrang, ...
PloS one 8 (12), e82813, 2013
1082013
Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice
H Sørensen, CL Brand, S Neschen, JJ Holst, K Fosgerau, E Nishimura, ...
Diabetes 55 (10), 2843-2848, 2006
1042006
The novel GLP‐1‐gastrin dual agonist, ZP3022, increases β‐cell mass and prevents diabetes in db/db mice
K Fosgerau, L Jessen, J Lind Tolborg, T Østerlund, K Schaeffer Larsen, ...
Diabetes, Obesity and Metabolism 15 (1), 62-71, 2013
992013
Compartmentation of lactate originating from glycogen and glucose in cultured astrocytes
HM Sickmann, A Schousboe, K Fosgerau, HS Waagepetersen
Neurochemical research 30, 1295-1304, 2005
722005
Drug-induced mild therapeutic hypothermia obtained by administration of a transient receptor potential vanilloid type 1 agonist
K Fosgerau, UJ Weber, JW Gotfredsen, M Jayatissa, C Buus, ...
BMC cardiovascular disorders 10, 1-10, 2010
532010
40th EASD Annual Meeting of the European Association for the Study of Diabetes: Munich, Germany, 5–9 September 2004
M Veitenhansl, K Stegner, FX Hierl, C Dieterle, H Feldmeier, B Gutt, ...
Diabetologia 47, A1-A464, 2004
512004
Treatment of cardiac conditions
JS Petersen, AL Kjoelbye, M Skovgaard, HD Pedersen, L Axelsen, ...
US Patent App. 13/574,197, 2013
442013
Novel GLP-1/GLP-2 co-agonists display marked effects on gut volume and improves glycemic control in mice
P Wismann, SL Pedersen, G Hansen, K Mannerstedt, PJ Pedersen, ...
Physiology & behavior 192, 72-81, 2018
392018
The novel GLP-1–gastrin dual agonist ZP3022 improves glucose homeostasis and increases β-cell mass without affecting islet number in db/db mice
LS Dalbøge, DLC Almholt, TSR Neerup, N Vrang, J Jelsing, K Fosgerau
Journal of Pharmacology and Experimental Therapeutics 350 (2), 353-360, 2014
392014
Glucagon analogues
JL Tolborg, K Fosgerau, P Nørregaard, R Just, D Riber, DW Hamprecht, ...
US Patent 9,180,169, 2015
382015
Interleukin-6 autoantibodies are involved in the pathogenesis of a subset of type 2 diabetes
K Fosgerau, P Galle, T Hansen, A Albrechtsen, CL Rieper, BK Pedersen, ...
Journal of endocrinology 204 (3), 265, 2010
342010
The anti-diabetic effects of GLP-1-gastrin dual agonist ZP3022 in ZDF rats
J Skarbaliene, T Secher, J Jelsing, TSR Neerup, N Billestrup, K Fosgerau
Peptides 69, 47-55, 2015
302015
Novel α-MSH analog causes weight loss in obese rats and minipigs and improves insulin sensitivity
K Fosgerau, K Raun, C Nilsson, K Dahl, BS Wulff
The Journal of Endocrinology 220 (2), 97, 2014
302014
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