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Lene Axelsen
Lene Axelsen
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Gap junctions
MS Nielsen, LN Axelsen, PL Sorgen, V Verma, M Delmar, ...
Comprehensive Physiology 2 (3), 2012
5182012
Identification of ischemia-regulated phosphorylation sites in connexin43: a possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123)
LN Axelsen, M Stahlhut, S Mohammed, BD Larsen, MS Nielsen, ...
Journal of molecular and cellular cardiology 40 (6), 790-798, 2006
1612006
Managing the complexity of communication: regulation of gap junctions by post-translational modification
LN Axelsen, K Calloe, NH Holstein-Rathlou, MS Nielsen
Frontiers in pharmacology 4, 53537, 2013
1442013
Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation
LN Axelsen, JB Lademann, JS Petersen, NH Holstein-Rathlou, T Ploug, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2010
1032010
Sphingosine-1-phosphate reduces ischaemia–reperfusion injury by phosphorylating the gap junction protein Connexin43
S Morel, C Christoffersen, LN Axelsen, F Montecucco, V Rochemont, ...
Cardiovascular research 109 (3), 385-396, 2016
632016
Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis
LN Axelsen, K Calloe, TH Braunstein, M Riemann, JP Hofgaard, B Liang, ...
Cardiovascular diabetology 14, 1-14, 2015
612015
Treatment of cardiac conditions
JS Petersen, AL Kjoelbye, M Skovgaard, HD Pedersen, L Axelsen, ...
US Patent App. 13/574,197, 2013
442013
Glucagon and a glucagon‐GLP‐1 dual‐agonist increases cardiac performance with different metabolic effects in insulin‐resistant hearts
LN Axelsen, W Keung, HD Pedersen, E Meier, D Riber, AL Kjølbye, ...
British Journal of Pharmacology 165 (8), 2736-2748, 2012
382012
Antiarrhythmic mechanisms of SK channel inhibition in the rat atrium
L Skibsbye, X Wang, LN Axelsen, SH Bomholtz, MS Nielsen, M Grunnet, ...
Journal of cardiovascular pharmacology 66 (2), 165-176, 2015
322015
Metabolic and cardiac changes in high cholesterol–fructose-fed rats
LN Axelsen, HD Pedersen, JS Petersen, NH Holstein-Rathlou, AL Kjølbye
Journal of pharmacological and toxicological methods 61 (3), 292-296, 2010
322010
Myocardial impulse propagation is impaired in right ventricular tissue of Zucker diabetic fatty (ZDF) rats
KB Olsen, LN Axelsen, TH Braunstein, CM Sørensen, CB Andersen, ...
Cardiovascular Diabetology 12, 1-11, 2013
302013
Increasing gap junctional coupling: a tool for dissecting the role of gap junctions
LN Axelsen, K Haugan, M Stahlhut, AL Kjølbye, JK Hennan, ...
Journal of membrane biology 216, 23-35, 2007
272007
Angiotensin II does not acutely regulate conduction velocity in rat atrial tissue
KB Olsen, TH Braunstein, CM Sørensen, LN Axelsen, ...
Scandinavian Journal of Clinical and Laboratory Investigation 71 (6), 492-499, 2011
112011
Clopidogrel, a CYP2C8 inhibitor, causes a clinically relevant increase in the systemic exposure to the active metabolite of selexipag in healthy subjects
LN Axelsen, I Poggesi, F Rasschaert, JJ Perez Ruixo, S Bruderer
British Journal of Clinical Pharmacology 87 (1), 119-128, 2021
102021
Serine 297 and serine 306: two new phosphorylation sites involved in the regulation of connexin43 during ischemia
L Axelsen, S Mohammed, A Kjolbye, MS Nielsen, N Holstein-Rathlou, ...
62005
Safety, tolerability and pharmacokinetics study in patients with pulmonary arterial hypertension (PAH) temporarily switching from oral to IV selexipag
H Klose, K Chin, R Ewert, H Gall, J Parambil, D Poch, H Seyfarth, ...
The Journal of Heart and Lung Transplantation 38 (4), S490, 2019
42019
Temporarily switching from oral to intravenous selexipag in patients with pulmonary arterial hypertension: safety, tolerability, and pharmacokinetic results from an open-label …
H Klose, KM Chin, R Ewert, H Gall, J Parambil, D Poch, HJ Seyfarth, ...
Respiratory Research 22, 1-9, 2021
32021
Acute intramyocardial lipid accumulation in rats does not slow cardiac conduction per se
CF Jensen, ED Bartels, TH Braunstein, LB Nielsen, NH Holstein‐Rathlou, ...
Physiological Reports 7 (7), e14049, 2019
32019
Diet-induced hypertension in rats is associated with increased renal vasoconstrictor response to angiotensin II after imitated endothelial dysfunction
LJ Jensen, MAV Lund, M Salomonsson, JP Goetze, TE Jonassen, ...
Microvascular Research 141, 104333, 2022
2022
Treatment of cardiac conditions
BD Larsen, RS Hansen, K Fosgerau, L Axelsen, JS Petersen, ...
2014
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Artikler 1–20