Hugues Abriel

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Jean-Sebastien RougierSenior Teaching and Research assistant, Universitiy of Bern, SwitzerlandVerified email at ibmm.unibe.ch
Olivier StaubUniversity of LausanneVerified email at unil.ch
Mohamed Yassine AmarouchProfessor of Physiology, Multidisciplinary Faculty of Taza, University Sidi Mohamed Ben Abdallah ofVerified email at usmba.ac.ma
Thomas JespersenProfessor, University of CopenhagenVerified email at sund.ku.dk
Ludovic GilletClinical Scientist - Roche Diagnostics InternationalVerified email at roche.com
Alain CoulombeICAN - Institute of CardioMetabolism and Nutrition Sorbonne Université, Paris, France Faculté deVerified email at upmc.fr
Thierry PedrazziniUniversity of Lausanne Medical SchoolVerified email at chuv.ch
vincent probstuniversité de nantesVerified email at chu-nantes.fr
Xander Wehrens, MD PhDDirector, Cardiovascular Research Institute, Baylor College of MedicineVerified email at bcm.edu
Carlo NapolitanoUniversity of Pavia and Molecular Cardiology ICS Maugeri, Pavia, ItalyVerified email at fsm.it
Silvia G Priori, MD ,PhDICS Maugeri, IRCCS; Dept Molecular Medicine, Univ of Pavia, Italy -Verified email at fsm.it
Candido CaboNew York City College of Technology/CUNY and Courant Institute/New York UniversityVerified email at citytech.cuny.edu
Andrea DomenighettiShirley Ryan AbilityLabVerified email at sralab.org
Ozhathil Lijo CherianBiomedical Institute, University of Copenhagen, Denmark.Verified email at sund.ku.dk
Søren-Peter OlesenProfessor, University of CopenhagenVerified email at sund.ku.dk
Johannes LoffingUniversity of ZurichVerified email at anatom.uzh.ch
Jacques S BeckmannProf emeritus, UNILVerified email at unil.ch
panos vardasHygeia Hospitals groupVerified email at med.uoc.gr
Alban-Elouen BaruteauL'institut du thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, FranceVerified email at chu-nantes.fr
Peter J MohlerOhio State UniversityVerified email at osumc.edu

Hugues Abriel

Inst. of Biochemistry and Molecular Medicine, University of Bern, Switzerland

Verified email at ibmm.unibe.ch - Homepage

ion channels channelopathies cardiac electrophysiology cellular electrophysiology


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Defective regulation of the epithelial Na⁺ channel by Nedd4 in Liddle's syndrome H Abriel, J Loffing, JF Rebhun, JH Pratt, L Schild, JD Horisberger, D Rotin, ... The Journal of clinical investigation 103 (5), 667-673, 1999	430	1999
Stereoselective Block of hERG Channel by (S)‐Methadone and QT Interval Prolongation in CYP2B6 Slow Metabolizers CB Eap, S Crettol, JS Rougier, J Schläpfer, L Sintra Grilo, JJ Déglon, ... Clinical Pharmacology & Therapeutics 81 (5), 719-728, 2007	296	2007
Cardiac sodium channel Nav1. 5 and interacting proteins: physiology and pathophysiology H Abriel Journal of molecular and cellular cardiology 48 (1), 2-11, 2010	279	2010
Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination O Staub, H Abriel, P Plant, T Ishikawa, V Kanelis, R Saleki, ... Kidney international 57 (3), 809-815, 2000	261	2000
Characterization of sodium channel α-and β-subunits in rat and mouse cardiac myocytes JD Malhotra, C Chen, I Rivolta, H Abriel, R Malhotra, LN Mattei, ... Circulation 103 (9), 1303-1310, 2001	248	2001
Cardiac Sodium Channel Na_v1.5 Is Regulated by a Multiprotein Complex Composed of Syntrophins and Dystrophin B Gavillet, JS Rougier, AA Domenighetti, R Behar, C Boixel, P Ruchat, ... Circulation research 99 (4), 407-414, 2006	247	2006
SAP97 and Dystrophin Macromolecular Complexes Determine Two Pools of Cardiac Sodium Channels Na_v1.5 in Cardiomyocytes S Petitprez, AF Zmoos, J Ogrodnik, E Balse, N Raad, S El-Haou, M Albesa, ... Circulation research 108 (3), 294-304, 2011	244	2011
Cardiac Voltage-Gated Sodium Channel Na_v1.5 Is Regulated by Nedd4-2 Mediated Ubiquitination MX Van Bemmelen, JS Rougier, B Gavillet, F Apothéloz, D Daidié, ... Circulation research 95 (3), 284-291, 2004	229	2004
Brugada syndrome and fever: Genetic and molecular characterization of patients carrying SCN5A mutations DI Keller, JS Rougier, JP Kucera, N Benammar, V Fressart, P Guicheney, ... Cardiovascular research 67 (3), 510-519, 2005	214	2005
Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes I Rivolta, H Abriel, M Tateyama, H Liu, M Memmi, P Vardas, C Napolitano, ... Journal of Biological Chemistry 276 (33), 30623-30630, 2001	212	2001
Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6) C Templin, JR Ghadri, JS Rougier, A Baumer, V Kaplan, M Albesa, ... European heart journal 32 (9), 1077-1088, 2011	206	2011
Regulation of the voltage-gated cardiac sodium channel Nav1. 5 by interacting proteins H Abriel, RS Kass Trends in cardiovascular medicine 15 (1), 35-40, 2005	188	2005
Nedd4. 1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding V Blot, F Perugi, B Gay, MC Prévost, L Briant, F Tangy, H Abriel, O Staub, ... Journal of cell science 117 (11), 2357-2367, 2004	168	2004
Cardiac sodium channel NaV1. 5 distribution in myocytes via interacting proteins: the multiple pool model D Shy, L Gillet, H Abriel Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1833 (4), 886-894, 2013	161	2013
Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins JS Rougier, MX van Bemmelen, MC Bruce, T Jespersen, B Gavillet, ... American Journal of Physiology-Cell Physiology 288 (3), C692-C701, 2005	153	2005
Novel Arrhythmogenic Mechanism Revealed by a Long-QT Syndrome Mutation in the Cardiac Na⁺ Channel H Abriel, C Cabo, XHT Wehrens, I Rivolta, HK Motoike, M Memmi, ... Circulation research 88 (7), 740-745, 2001	145	2001
The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family T Jespersen, M Membrez, CS Nicolas, B Pitard, O Staub, SP Olesen, ... Cardiovascular research 74 (1), 64-74, 2007	144	2007
Molecular genetics and functional anomalies in a series of 248 Brugada cases with 11 mutations in the TRPM4 channel H Liu, S Chatel, C Simard, N Syam, L Salle, V Probst, J Morel, G Millat, ... PloS one 8 (1), e54131, 2013	140	2013
Cardiac channelopathies: genetic and molecular mechanisms H Abriel, EV Zaklyazminskaya Gene 517 (1), 1-11, 2013	139	2013
Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4 H Abriel, E Kamynina, JD Horisberger, O Staub FEBS letters 466 (2-3), 377-380, 2000	136	2000

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