| Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus K Shin-ya, K Wierzba, K Matsuo, T Ohtani, Y Yamada, K Furihata, ... Journal of the American Chemical Society 123 (6), 1262-1263, 2001 | 694 | 2001 |
| Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular G-quadruplex MY Kim, H Vankayalapati, K Shin-Ya, K Wierzba, LH Hurley Journal of the American Chemical Society 124 (10), 2098-2099, 2002 | 692 | 2002 |
| Terpene synthases are widely distributed in bacteria Y Yamada, T Kuzuyama, M Komatsu, K Shin-Ya, S Omura, DE Cane, ... Proceedings of the National Academy of Sciences 112 (3), 857-862, 2015 | 486 | 2015 |
| FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability Y Wu, K Shin-ya, RM Brosh Jr Molecular and cellular biology 28 (12), 4116-4128, 2008 | 445 | 2008 |
| Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure J Seenisamy, S Bashyam, V Gokhale, H Vankayalapati, D Sun, ... Journal of the American Chemical Society 127 (9), 2944-2959, 2005 | 373 | 2005 |
| Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action A De Cian, G Cristofari, P Reichenbach, E De Lemos, D Monchaud, ... Proceedings of the National Academy of Sciences 104 (44), 17347-17352, 2007 | 329 | 2007 |
| Engineered Streptomyces avermitilis Host for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites M Komatsu, K Komatsu, H Koiwai, Y Yamada, I Kozone, M Izumikawa, ... ACS synthetic biology 2 (7), 384-396, 2013 | 274 | 2013 |
| Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia T Tauchi, K Shin-Ya, G Sashida, M Sumi, S Okabe, JH Ohyashiki, ... Oncogene 25 (42), 5719-5725, 2006 | 274 | 2006 |
| G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3′ telomeric overhang in … H Tahara, K Shin-Ya, H Seimiya, H Yamada, T Tsuruo, T Ide Oncogene 25 (13), 1955-1966, 2006 | 267 | 2006 |
| Effect on tumor cells of blocking survival response to glucose deprivation HR Park, A Tomida, S Sato, Y Tsukumo, J Yun, T Yamori, Y Hayakawa, ... Journal of the National Cancer Institute 96 (17), 1300-1310, 2004 | 256 | 2004 |
| Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways T Tauchi, K Shin-Ya, G Sashida, M Sumi, A Nakajima, T Shimamoto, ... Oncogene 22 (34), 5338-5347, 2003 | 253 | 2003 |
| The G-quadruplex Ligand Telomestatin Inhibits POT1 Binding to Telomeric Sequences In vitro and Induces GFP-POT1 Dissociation from Telomeres in Human Cells D Gomez, MF O'Donohue, T Wenner, C Douarre, J Macadré, P Koebel, ... Cancer research 66 (14), 6908-6912, 2006 | 250 | 2006 |
| Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells D Gomez, T Wenner, B Brassart, C Douarre, MF O'Donohue, V El Khoury, ... Journal of Biological Chemistry 281 (50), 38721-38729, 2006 | 240 | 2006 |
| Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters H Ikeda, K Shin-ya, S Omura Journal of Industrial Microbiology and Biotechnology 41 (2), 233-250, 2014 | 215 | 2014 |
| Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands PS Shirude, ER Gillies, S Ladame, F Godde, K Shin-Ya, I Huc, ... Journal of the American Chemical Society 129 (39), 11890-11891, 2007 | 195 | 2007 |
| Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice M Nishio, K Sugimachi, H Goto, J Wang, T Morikawa, Y Miyachi, Y Takano, ... Proceedings of the National Academy of Sciences 113 (1), E71-E80, 2016 | 193 | 2016 |
| Interaction of telomestatin with the telomeric single-strand overhang D Gomez, R Paterski, T Lemarteleur, K Shin-Ya, JL Mergny, JF Riou Journal of Biological Chemistry 279 (40), 41487-41494, 2004 | 180 | 2004 |
| Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation S Saito, A Furuno, J Sakurai, A Sakamoto, HR Park, K Shin-Ya, T Tsuruo, ... Cancer research 69 (10), 4225-4234, 2009 | 178 | 2009 |
| Mammalian DNA2 helicase/nuclease cleaves G‐quadruplex DNA and is required for telomere integrity W Lin, S Sampathi, H Dai, C Liu, M Zhou, J Hu, Q Huang, J Campbell, ... The EMBO journal 32 (10), 1425-1439, 2013 | 177 | 2013 |
| Apoptolidin, a new apoptosis inducer in transformed cells from Nocardiopsis sp. JW Kim, H Adachi, K Shin-Ya, Y Hayakawa, H Seto The Journal of antibiotics 50 (7), 628-630, 1997 | 165 | 1997 |
