Jean-Baptiste Dupont
Jean-Baptiste Dupont
Postdoctoral fellow, I-Stem, Muscular Diseases
Verified email at istem.fr - Homepage
TitleCited byYear
Advanced characterization of DNA molecules in rAAV vector preparations by single-stranded virus next-generation sequencing
E Lecomte, B Tournaire, B Cogné, JB Dupont, P Lindenbaum, ...
Molecular Therapy-Nucleic Acids 4, e260, 2015
312015
Short-lived recombinant adeno-associated virus transgene expression in dystrophic muscle is associated with oxidative damage to transgene mRNA
JB Dupont, B Tournaire, C Georger, B Marolleau, L Jeanson-Leh, ...
Molecular Therapy-Methods & Clinical Development 2, 15010, 2015
142015
NGS library preparation may generate artifactual integration sites of AAV vectors
B Cogne, R Snyder, P Lindenbaum, JB Dupont, R Redon, P Moullier, ...
Nature medicine 20 (6), 577, 2014
92014
Restriction Factors Against Recombinant Adeno-associated Virus Vectormediated Gene Transfer in Dystrophin-deficient Muscles
JB Dupont
Current gene therapy 16 (3), 168-183, 2016
12016
AAV-mediated gene transfer restores a normal muscle transcriptome in a canine model of X-linked myotubular myopathy
JB Dupont, J Guo, E Renaud-Gabardos, K Poulard, V Latournerie, ...
Molecular Therapy 28 (2), 382-393, 2020
2020
Improvement of pluripotent stem cell-derived skeletal muscle myotube maturation through the combination of physical and chemical factors
JB Dupont, E Massourides, V Mournetas, SM Luttrell, DL Mack, C Pinset
HUMAN GENE THERAPY 30 (11), A131-A132, 2019
2019
Single cell developmental trajectories reveal early phenotypes in Duchenne muscular dystrophy prior to skeletal muscle commitment
JB Dupont, SM Luttrell, D Jackson, JS Packer, L Maves, C Trapnell, ...
HUMAN GENE THERAPY 30 (11), A123-A123, 2019
2019
Rescue of Canine XL-MTM MicroRNA Transcriptome via Gene Transfer
N Duncan, JB Dupont, DL Mack
2019
Myogenesis modelled by human pluripotent stem cells uncovers Duchenne muscular dystrophy phenotypes prior to skeletal muscle commitment
V Mournetas, E Massouridès, JB Dupont, E Kornobis, H Polvèche, ...
bioRxiv, 720920, 2019
2019
Gene Therapy for X-Linked Myotubular Myopathy
JB Dupont, MW Lawlor, MK Childers
Muscle Gene Therapy, 565-577, 2019
2019
Gene Therapy Leads to Dose-Dependent Transcriptome Remodeling and Provides Biomarkers of Therapeutic Efficacy in X-Linked Myotubular Myopathy
JB Dupont, J Guo, JT Gray, A Buj-Bello, MK Childers, DL Mack
MOLECULAR THERAPY 26 (5), 5-6, 2018
2018
High-throughput transcriptome analysis provides new indicators of gene therapy efficacy in XLMTM dogs
J Dupont, J Guo, J Gray, A Buj-Bello, M Childers, D Mack
Neuromuscular Disorders 27, S171, 2017
2017
RNA-Seq Tag Counting: An Approach for Quantifying the Relative Expression of Vector-Derived and Endogenous Genes in rAAV-Treated Non-Clinical Models
J Guo, JB Dupont, T Stinchcombe, MK Childers, DL Mack, JT Gray
MOLECULAR THERAPY 25 (5), 49-50, 2017
2017
RNA-Seq Analysis of Canine X-Linked Myotubular Myopathy Muscles Before and After Gene Therapy
JB Dupont, J Guo, JT Gray, A Buj-Bello, MK Childers, DL Mack
MOLECULAR THERAPY 25 (5), 101-101, 2017
2017
Impact d’un traitement antioxydant sur le transfert de gène par un vecteur AAVr dans un modèle murin de la dystrophie musculaire de Duchenne
JB Dupont, B Tournaire, R Durand, B Marolleau, É Bertil, C Georger, ...
Les Cahiers de Myologie, 99-101, 2016
2016
390. Impact of a Treatment with Antioxidant on Gene Transfer Efficiency After Recombinant Adeno-Associated Vector Injection in a Mouse Model of Duchenne Muscular Dystrophy
JB Dupont, B Tournaire, R Durand, B Marolleau, E Bertil, C Georger, ...
Molecular Therapy 24, S155, 2016
2016
Insight into molecular events associated with partial restriction of Adeno-Associated Vector genome expression in dystrophic muscles
JB Dupont, B Tournaire, L Jeanson-Leh, L Dubreil, C Georger, ...
HUMAN GENE THERAPY 24 (12), A40-A40, 2013
2013
76. Epigenetic Alterations in the Dystrophic Muscle Environment Down-Regulate rAAV-Mediated Transgene Expression
JB Dupont, B Tournaire, C Georger, L Van Wittenberghe, B Marolleau, ...
Molecular Therapy 21, 1, 2013
2013
The Murine Dystrophic Muscle Environment Reduces Adeno-Associated Virus Vector-mediated Transgene Expression
JB Dupont, A Leger, M Penaud-Budloo, E Bertil, C Georger, R Snyder, ...
HUMAN GENE THERAPY 23 (10), A130-A130, 2012
2012
Reversibelt hydraulisk aksialstrømningsmaskine.
J Dupont, G Martin
1969
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Articles 1–20