Ngee Han Lim
Ngee Han Lim
KTRR/ARUK Research Fellow, Oxford University
Verified email at - Homepage
Cited by
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Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis
A Kinloch, K Lundberg, R Wait, N Wegner, NH Lim, AJW Zendman, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2008
Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4
C Gendron, M Kashiwagi, NH Lim, JJ Enghild, IB Thøgersen, C Hughes, ...
Journal of Biological Chemistry 282 (25), 18294-18306, 2007
Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice
B Seubert, B Grünwald, J Kobuch, H Cui, F Schelter, S Schaten, JT Siveke, ...
Hepatology 61 (1), 238-248, 2015
X-ray structure of human proMMP-1: new insights into procollagenase activation and collagen binding
D Jozic, G Bourenkov, NH Lim, R Visse, H Nagase, W Bode, K Maskos
Journal of Biological Chemistry 280 (10), 9578-9585, 2005
TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2
WM Wang, G Ge, NH Lim, H Nagase, DS Greenspan
Biochemical Journal 398 (3), 515-519, 2006
Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity
K Fushimi, L Troeberg, H Nakamura, NH Lim, H Nagase
Journal of Biological Chemistry 283 (11), 6706-6716, 2008
Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications
NH Lim, M Kashiwagi, R Visse, J Jones, JJ Enghild, K Brew, H Nagase
Biochemical Journal 431 (1), 113-122, 2010
N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential …
E Nuti, F Casalini, SI Avramova, S Santamaria, G Cercignani, L Marinelli, ...
Journal of medicinal chemistry 52 (15), 4757-4773, 2009
A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons
A Ould-yahoui, E Tremblay, O Sbai, L Ferhat, A Bernard, E Charrat, ...
PloS one 4 (12), e8289, 2009
In vivo fluorescence imaging of E‐selectin: Quantitative detection of endothelial activation in a mouse model of arthritis
LL Gompels, L Madden, NH Lim, JJ Inglis, E McConnell, TL Vincent, ...
Arthritis & Rheumatism 63 (1), 107-117, 2011
In vivo optical imaging in arthritis—an enlightening future?
LL Gompels, NH Lim, T Vincent, EM Paleolog
Rheumatology 49 (8), 1436-1446, 2010
DOTAM derivatives as active cartilage-targeting drug carriers for the treatment of osteoarthritis
HY Hu, NH Lim, D Ding-Pfennigdorff, J Saas, KU Wendt, O Ritzeler, ...
Bioconjugate chemistry 26 (3), 383-388, 2015
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation
D Caglič, A Globisch, M Kindermann, NH Lim, V Jeske, HP Juretschke, ...
Bioorganic & medicinal chemistry 19 (3), 1055-1061, 2011
Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity
M Bekhouche, D Kronenberg, S Vadon-Le Goff, C Bijakowski, NH Lim, ...
Journal of Biological Chemistry 285 (21), 15950-15959, 2010
Targeting of viral interleukin-10 with an antibody fragment specific to damaged arthritic cartilage improves its therapeutic potency
C Hughes, A Sette, M Seed, F D’Acquisto, A Manzo, TL Vincent, NH Lim, ...
Arthritis research & therapy 16, 1-11, 2014
In vivo imaging of MMP-13 activity in the murine destabilised medial meniscus surgical model of osteoarthritis
NH Lim, E Meinjohanns, M Meldal, G Bou-Gharios, H Nagase
Osteoarthritis and cartilage 22 (6), 862-868, 2014
In vivo imaging of matrix metalloproteinase 12 and matrix metalloproteinase 13 activities in the mouse model of collagen‐induced arthritis
NH Lim, E Meinjohanns, G Bou‐Gharios, LL Gompels, E Nuti, A Rossello, ...
Arthritis & rheumatology 66 (3), 589-598, 2014
In Vivo Imaging of MMP‐13 Activity Using a Specific Polymer‐FRET Peptide Conjugate Detects Early Osteoarthritis and Inhibitor Efficacy
A Duro‐Castano, NH Lim, I Tranchant, M Amoura, F Beau, H Wieland, ...
Advanced Functional Materials 28 (37), 1802738, 2018
In vivo visualization of osteoarthritic hypertrophic lesions
HY Hu, NH Lim, HP Juretschke, D Ding-Pfennigdorff, P Florian, ...
Chemical Science 6 (11), 6256-6261, 2015
Generation of a mouse line harboring a bi‐transgene expressing luciferase and tamoxifen‐activatable creERT2 recombinase in cartilage
LL Cascio, K Liu, H Nakamura, G Chu, NH Lim, A Chanalaris, ...
genesis 52 (2), 110-119, 2014
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