Netaly Khazanov
Netaly Khazanov
Ph D Chemistry
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Sliding of p53 along DNA can be modulated by its oligomeric state and by cross-talks between its constituent domains
N Khazanov, Y Levy
Journal of molecular biology 408 (2), 335-355, 2011
Plant phenolic volatiles inhibit quorum sensing in pectobacteria and reduce their virulence by potential binding to ExpI and ExpR proteins
JR Joshi, N Khazanov, H Senderowitz, S Burdman, A Lipsky, I Yedidia
Scientific reports 6 (1), 1-15, 2016
Challenging a paradigm: Theoretical calculations of the protonation state of the Cys25‐His159 catalytic diad in free papain
M Shokhen, N Khazanov, A Albeck
Proteins: Structure, Function, and Bioinformatics 77 (4), 916-926, 2009
Asymmetric DNA-search dynamics by symmetric dimeric proteins
N Khazanov, A Marcovitz, Y Levy
Biochemistry 52 (32), 5335-5344, 2013
The mechanism of papain inhibition by peptidyl aldehydes
M Shokhen, N Khazanov, A Albeck
Proteins: Structure, Function, and Bioinformatics 79 (3), 975-985, 2011
Guaiacol as a drug candidate for treating adult polyglucosan body disease
O Kakhlon, I Ferreira, LJ Solmesky, N Khazanov, A Lossos, R Alvarez, ...
JCI insight 3 (17), 2018
Specific stabilization of CFTR by phosphatidylserine
E Hildebrandt, N Khazanov, JC Kappes, Q Dai, H Senderowitz, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (2), 289-293, 2017
Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1
Z Yang, E Hildebrandt, F Jiang, AA Aleksandrov, N Khazanov, Q Zhou, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (5), 1193-1204, 2018
Screening of the active site from water by the incoming ligand triggers catalysis and inhibition in serine proteases
M Shokhen, N Khazanov, A Albeck
Proteins: Structure, Function, and Bioinformatics 70 (4), 1578-1587, 2008
Potentiators exert distinct effects on human, murine, and Xenopus CFTR
G Cui, N Khazanov, BB Stauffer, DT Infield, BR Imhoff, H Senderowitz, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (2 …, 2016
The cooperative effect between active site ionized groups and water desolvation controls the alteration of acid/base catalysis in serine proteases
M Shokhen, N Khazanov, A Albeck
ChemBioChem 8 (12), 1416-1421, 2007
Hsp104 facilitates the endoplasmic‐reticulum–associated degradation of disease‐associated and aggregation‐prone substrates
LM Doonan, CJ Guerriero, GM Preston, TM Buck, N Khazanov, EA Fisher, ...
Protein Science 28 (7), 1290-1306, 2019
A novel image-based high-throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease
LJ Solmesky, N Khazanov, H Senderowitz, P Wang, BA Minassian, ...
Biochemical Journal 474 (20), 3403-3420, 2017
Enzyme isoselective inhibitors: Application to drug design
M Shokhen, N Khazanov, A Albeck
ChemMedChem: Chemistry Enabling Drug Discovery 1 (6), 639-643, 2006
Novel inhibitors of leukocyte transendothelial migration
T Getter, R Margalit, S Kahremany, L Levy, E Blum, N Khazanov, ...
Bioorganic chemistry 92, 103250, 2019
Enzyme Isoselective Inhibitors: A Tool for Binding‐Trend Analysis
R Ozeri, N Khazanov, N Perlman, M Shokhen, A Albeck
ChemMedChem: Chemistry Enabling Drug Discovery 1 (6), 631-638, 2006
An ancient CFTR ortholog informs molecular evolution in ABC transporters
G Cui, J Hong, YW Chung-Davidson, D Infield, X Xu, J Li, L Simhaev, ...
Developmental cell 51 (4), 421-430. e3, 2019
Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator
C Wang, AA Aleksandrov, Z Yang, F Forouhar, EA Proctor, P Kota, J An, ...
Journal of Biological Chemistry 293 (46), 17685-17704, 2018
Design of compact biomimetic cellulose binding peptides as carriers for cellulose catalytic degradation
N Khazanov, T Iline-Vul, E Noy, G Goobes, H Senderowitz
The Journal of Physical Chemistry B 120 (2), 309-319, 2016
Discovery and Design of Novel Small Molecule GSK-3 Inhibitors Targeting the Substrate Binding Site
I Rippin, N Khazanov, S Ben Joseph, T Kudinov, E Berent, ...
International journal of molecular sciences 21 (22), 8709, 2020
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