Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression R Bergholdt, C Brorsson, A Palleja, LA Berchtold, T Fløyel, ... Diabetes 61 (4), 954-962, 2012 | 147 | 2012 |
TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells L Marroqui, RS Dos Santos, T Fløyel, FA Grieco, I Santin, A Op de Beeck, ... Diabetes 64 (11), 3808-3817, 2015 | 125 | 2015 |
CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients T Fløyel, C Brorsson, LB Nielsen, M Miani, CH Bang-Berthelsen, ... Proceedings of the National Academy of Sciences 111 (28), 10305-10310, 2014 | 93 | 2014 |
Low versus high carbohydrate diet in type 1 diabetes: a 12‐week randomized open‐label crossover study S Schmidt, MB Christensen, N Serifovski, C Damm‐Frydenberg, ... Diabetes, Obesity and Metabolism 21 (7), 1680-1688, 2019 | 69 | 2019 |
Independent component and pathway-based analysis of miRNA-regulated gene expression in a model of type 1 diabetes CH Bang-Berthelsen, L Pedersen, T Fløyel, PH Hagedorn, T Gylvin, ... BMC genomics 12, 1-11, 2011 | 50 | 2011 |
Genes affecting β-cell function in type 1 diabetes T Fløyel, S Kaur, F Pociot Current diabetes reports 15, 1-11, 2015 | 46 | 2015 |
The genetic and regulatory architecture of ERBB3-type 1 diabetes susceptibility locus S Kaur, AH Mirza, CA Brorsson, T Fløyel, J Størling, HB Mortensen, ... Molecular and Cellular Endocrinology 419, 83-91, 2016 | 41 | 2016 |
Increased levels of inflammatory factors are associated with severity of polyneuropathy in type 1 diabetes T Okdahl, C Brock, T Fløyel, AML Wegeberg, PE Jakobsen, N Ejskjaer, ... Clinical endocrinology 93 (4), 419-428, 2020 | 20 | 2020 |
Circulating inflammatory markers are inversely associated with heart rate variability measures in type 1 diabetes AML Wegeberg, T Okdahl, T Fløyel, C Brock, N Ejskjaer, S Riahi, F Pociot, ... Mediators of inflammation 2020, 2020 | 19 | 2020 |
Op de Beeck A, Marselli L, Marchetti P, Pociot F, Eizirik DL. TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic … L Marroqui, RS Dos Santos, T Floyel, FA Grieco, I Santin Diabetes 64 (11), 3808-3817, 2015 | 17 | 2015 |
CEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targets D Barbagallo, AG Condorelli, S Piro, N Parrinello, T Fløyel, M Ragusa, ... Molecular Biology of the Cell 25 (16), 2333-2341, 2014 | 17 | 2014 |
MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage AL Vestergaard, CH Bang-Berthelsen, T Fløyel, JL Stahl, L Christen, ... Plos one 13 (9), 2018 | 15 | 2018 |
MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage A Lindeløv Vestergaard, C Heiner Bang-Berthelsen, T Fløyel, ... PLoS One 13 (9), e0203713, 2018 | 12 | 2018 |
The Rac2 GTPase contributes to cathepsin H-mediated protection against cytokine-induced apoptosis in insulin-secreting cells T Fløyel, AH Mirza, S Kaur, C Frørup, R Yarani, J Størling, F Pociot Molecular and cellular endocrinology 518, 110993, 2020 | 10 | 2020 |
SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients T Fløyel, K Meyerovich, MC Prause, S Kaur, C Frørup, HB Mortensen, ... Diabetes 70 (2), 464-476, 2021 | 9 | 2021 |
Characterization of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells C Frørup, R Gerwig, CAS Svane, J Mendes Lopes de Melo, K Henriksen, ... Frontiers in Endocrinology 14, 1128523, 2023 | 5 | 2023 |
Cathepsin C Regulates Cytokine-Induced Apoptosis in β-Cell Model Systems T Fløyel, C Frørup, J Størling, F Pociot Genes 12 (11), 1694, 2021 | 5 | 2021 |
Novel monoclonal antibodies against Pdx1 reveal feedback regulation of Pdx1 protein levels T Galbo, IL Pedersen, T Fløyel, CH Bang-Berthelsen, P Serup, ... European Journal of Histochemistry: EJH 54 (2), 2010 | 5 | 2010 |
β Cell and autophagy: what do we know? HR Mohammadi-Motlagh, M Sadeghalvad, N Yavari, R Primavera, ... Biomolecules 13 (4), 649, 2023 | 4 | 2023 |
The gut-pancreas axis in type 1 diabetes–a focus on environmental factors T Fløyel, D Funda, VI Dodero, M Haupt-Jorgensen Frontiers in Endocrinology 14, 1270297, 2023 | | 2023 |