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Univ.-Prof. Dr. Andreas Koeberle
Univ.-Prof. Dr. Andreas Koeberle
Michael Popp Research Institute, University Innsbruck
Verificeret mail på uibk.ac.at - Startside
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Multi-target approach for natural products in inflammation
A Koeberle, O Werz
Drug discovery today 19 (12), 1871-1882, 2014
3092014
Licofelone suppresses prostaglandin E2 formation by interference with the inducible microsomal prostaglandin E2 synthase-1
A Koeberle, U Siemoneit, U Bühring, H Northoff, S Laufer, W Albrecht, ...
Journal of Pharmacology and Experimental Therapeutics 326 (3), 975-982, 2008
1962008
Inhibition of microsomal prostaglandin E2 synthase‐1 as a molecular basis for the anti‐inflammatory actions of boswellic acids from frankincense
U Siemoneit, A Koeberle, A Rossi, F Dehm, M Verhoff, S Reckel, TJ Maier, ...
British journal of pharmacology 162 (1), 147-162, 2011
1482011
Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo
A Rossi, R Di Paola, E Mazzon, T Genovese, R Caminiti, P Bramanti, ...
Journal of pharmacology and experimental therapeutics 329 (1), 76-86, 2009
1482009
Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo
A Rossi, R Di Paola, E Mazzon, T Genovese, R Caminiti, P Bramanti, ...
Journal of pharmacology and experimental therapeutics 329 (1), 76-86, 2009
1482009
Perspective of microsomal prostaglandin E2 synthase-1 as drug target in inflammation-related disorders
A Koeberle, O Werz
Biochemical pharmacology 98 (1), 1-15, 2015
1432015
Inhibitors of the microsomal prostaglandin E2 synthase-1 as alternative to non steroidal anti-inflammatory drugs (NSAIDs)-a critical review
A Koeberle, O Werz
Current medicinal chemistry 16 (32), 4274-4296, 2009
1432009
Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1
A Koeberle, H Northoff, O Werz
Molecular cancer therapeutics 8 (8), 2348-2355, 2009
1432009
The 5‐lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages
A Rossi, C Pergola, A Koeberle, M Hoffmann, F Dehm, P Bramanti, ...
British journal of pharmacology 161 (3), 555-570, 2010
1402010
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor
SC Koeberle, J Romir, S Fischer, A Koeberle, V Schattel, W Albrecht, ...
Nature chemical biology 8 (2), 141-143, 2012
1372012
Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1
J Bauer, S Kuehnl, JM Rollinger, O Scherer, H Northoff, H Stuppner, ...
Journal of Pharmacology and Experimental Therapeutics 342 (1), 169-176, 2012
1362012
Pirinixic Acid Derivatives as Novel Dual Inhibitors of Microsomal Prostaglandin E2 Synthase-1 and 5-Lipoxygenase
A Koeberle, H Zettl, C Greiner, M Wurglics, M Schubert-Zsilavecz, O Werz
Journal of medicinal chemistry 51 (24), 8068-8076, 2008
1362008
Revealing the macromolecular targets of complex natural products
D Reker, AM Perna, T Rodrigues, P Schneider, M Reutlinger, B Mönch, ...
Nature chemistry 6 (12), 1072-1078, 2014
1292014
Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo
J Bauer, A Koeberle, F Dehm, F Pollastro, G Appendino, H Northoff, ...
Biochemical pharmacology 81 (2), 259-268, 2011
1232011
Identification of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 as functional targets of the anti-inflammatory and anti-carcinogenic garcinol
A Koeberle, H Northoff, O Werz
Biochemical pharmacology 77 (9), 1513-1521, 2009
1222009
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase
H Pein, A Ville, S Pace, V Temml, U Garscha, M Raasch, K Alsabil, ...
Nature communications 9 (1), 3834, 2018
1142018
Cannflavins from hemp sprouts, a novel cannabinoid-free hemp food product, target microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase
O Werz, J Seegers, AM Schaible, C Weinigel, D Barz, A Koeberle, ...
PharmaNutrition 2 (3), 53-60, 2014
1122014
Myrtucommulone, a natural acylphloroglucinol, inhibits microsomal prostaglandin E2 synthase‐1
A Koeberle, F Pollastro, H Northoff, O Werz
British journal of pharmacology 156 (6), 952-961, 2009
1102009
Hyperforin, an anti-inflammatory constituent from St. John's wort, inhibits microsomal prostaglandin E2 synthase-1 and suppresses prostaglandin E2 formation in vivo
A Koeberle, A Rossi, J Bauer, L Verotta, O Werz
Frontiers in pharmacology 2, 9136, 2011
1062011
Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome
M Werner, PM Jordan, E Romp, A Czapka, Z Rao, C Kretzer, A Koeberle, ...
The FASEB Journal 33 (5), 6140, 2019
1042019
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Artikler 1–20