| Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates KS Hewitson, BMR Liénard, MA McDonough, IJ Clifton, D Butler, ... Journal of Biological Chemistry 282 (5), 3293-3301, 2007 | 262 | 2007 |
| Quantitative assessment of peptide sequence diversity in M13 combinatorial peptide phage display libraries DJ Rodi, AS Soares, L Makowski Journal of molecular biology 322 (5), 1039-1052, 2002 | 179 | 2002 |
| Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2 J Batra, J Robinson, AS Soares, AP Fields, DC Radisky, ES Radisky Journal of Biological Chemistry 287 (19), 15935-15946, 2012 | 128 | 2012 |
| Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE Díaz, ID Young, ... Science advances 7 (16), eabf8711, 2021 | 126 | 2021 |
| Acoustic injectors for drop-on-demand serial femtosecond crystallography CG Roessler, R Agarwal, M Allaire, R Alonso-Mori, B Andi, JFR Bachega, ... Structure 24 (4), 631-640, 2016 | 125 | 2016 |
| Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin DM Copeland, AS Soares, AH West, GB Richter-Addo Journal of inorganic biochemistry 100 (8), 1413-1425, 2006 | 123 | 2006 |
| Structural basis for NADH/NAD+ redox sensing by a Rex family repressor KJ McLaughlin, CM Strain-Damerell, K Xie, D Brekasis, AS Soares, ... Molecular cell 38 (4), 563-575, 2010 | 117 | 2010 |
| Acoustic methods for high-throughput protein crystal mounting at next-generation macromolecular crystallographic beamlines CG Roessler, A Kuczewski, R Stearns, R Ellson, J Olechno, AM Orville, ... Journal of synchrotron radiation 20 (5), 805-808, 2013 | 69 | 2013 |
| Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin S Moh'd A, AS Soares, A Hockla, ES Radisky Journal of biological chemistry 283 (7), 4115-4123, 2008 | 69 | 2008 |
| Crystal structure of a complex between the phosphorelay protein YPD1 and the response regulator domain of SLN1 bound to a phosphoryl analog X Zhao, DM Copeland, AS Soares, AH West Journal of molecular biology 375 (4), 1141-1151, 2008 | 65 | 2008 |
| The structures of penicillin-binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into β-lactam resistance TM Moon, ÉD D’Andréa, CW Lee, A Soares, J Jakoncic, C Desbonnet, ... Journal of Biological Chemistry 293 (48), 18574-18584, 2018 | 60 | 2018 |
| Acoustically mounted microcrystals yield high-resolution X-ray structures AS Soares, MA Engel, R Stearns, S Datwani, J Olechno, R Ellson, ... Biochemistry 50 (21), 4399-4401, 2011 | 53 | 2011 |
| Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes X Yin, A Scalia, L Leroy, CM Cuttitta, GM Polizzo, DL Ericson, ... Acta Crystallographica Section D: Biological Crystallography 70 (5), 1177-1189, 2014 | 51 | 2014 |
| Estimating the diversity of peptide populations from limited sequence data L Makowski, A Soares Bioinformatics 19 (4), 483-489, 2003 | 51 | 2003 |
| Determinants of affinity and proteolytic stability in interactions of Kunitz family protease inhibitors with mesotrypsin S Moh'd A, AS Soares, D Navaneetham, D Sinha, PN Walsh, ES Radisky Journal of biological chemistry 285 (47), 36884-36896, 2010 | 49 | 2010 |
| Matrix metalloproteinase-10/TIMP-2 structure and analyses define conserved core interactions and diverse exosite interactions in MMP/TIMP complexes J Batra, AS Soares, C Mehner, ES Radisky PLoS one 8 (9), e75836, 2013 | 47 | 2013 |
| The P2′ residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity MA Salameh, AS Soares, A Hockla, DC Radisky, ES Radisky Biochemical Journal 440 (1), 95-105, 2011 | 41 | 2011 |
| Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation J Batra, A Szabó, TR Caulfield, AS Soares, M Sahin-Toth, ES Radisky Journal of Biological Chemistry 288 (14), 9848-9859, 2013 | 40 | 2013 |
| Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin D Pendlebury, R Wang, RD Henin, A Hockla, AS Soares, BJ Madden, ... Journal of Biological Chemistry 289 (47), 32783-32797, 2014 | 33 | 2014 |
| Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site JH Carra, CA McHugh, S Mulligan, LAM Machiesky, AS Soares, ... BMC structural biology 7 (1), 1-11, 2007 | 32 | 2007 |
Robert SweetBrookhaven National LaboratoryVerified email at bnl.gov
