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John Paul Shen
John Paul Shen
Assistant Professor, University of Texas MD Anderson Cancer Center
Verified email at alum.mit.edu - Homepage
Title
Cited by
Cited by
Year
Integrated genomic characterization of papillary thyroid carcinoma
N Agrawal, R Akbani, B ŠArman Aksoy, A Ally, H Arachchi, SL Asa, ...
Cell 159 (3), 676-690, 2014
20532014
Network-based stratification of tumor mutations
M Hofree, JP Shen, H Carter, A Gross, T Ideker
Nature methods 10 (11), 1108-1115, 2013
8112013
Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions
JP Shen, D Zhao, R Sasik, J Luebeck, A Birmingham, ...
Nature methods 14 (6), 573-576, 2017
3042017
Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease
JE Bradner, R Mak, SK Tanguturi, R Mazitschek, SJ Haggarty, K Ross, ...
Proceedings of the National Academy of Sciences 107 (28), 12617-12622, 2010
2102010
A robust small-molecule microarray platform for screening cell lysates
JE Bradner, OM McPherson, R Mazitschek, D Barnes-Seeman, JP Shen, ...
Chemistry & biology 13 (5), 493-504, 2006
1502006
Genetic interaction mapping in mammalian cells using CRISPR interference
D Du, A Roguev, DE Gordon, M Chen, SH Chen, M Shales, JP Shen, ...
Nature methods 14 (6), 577-580, 2017
1442017
A network of conserved synthetic lethal interactions for exploration of precision cancer therapy
R Srivas, JP Shen, CC Yang, SM Sun, J Li, AM Gross, J Jensen, K Licon, ...
Molecular cell 63 (3), 514-525, 2016
1442016
Novel third-generation EGFR tyrosine kinase inhibitors and strategies to overcome therapeutic resistance in lung cancer
A Murtuza, A Bulbul, JP Shen, P Keshavarzian, BD Woodward, ...
Cancer Research 79 (4), 689-698, 2019
1352019
Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss
AM Gross, RK Orosco, JP Shen, AM Egloff, H Carter, M Hofree, ...
Nature genetics 46 (9), 939-943, 2014
1312014
A global transcriptional network connecting noncoding mutations to changes in tumor gene expression
W Zhang, A Bojorquez-Gomez, DO Velez, G Xu, KS Sanchez, JP Shen, ...
Nature genetics 50 (4), 613-620, 2018
1212018
Relative abundance of SARS-CoV-2 entry genes in the enterocytes of the lower gastrointestinal tract
JJ Lee, S Kopetz, E Vilar, JP Shen, K Chen, A Maitra
Genes 11 (6), 645, 2020
652020
Few-shot learning creates predictive models of drug response that translate from high-throughput screens to individual patients
J Ma, SH Fong, Y Luo, CJ Bakkenist, JP Shen, S Mourragui, LFA Wessels, ...
Nature Cancer 2 (2), 233-244, 2021
552021
Disruption of NSD1 in Head and Neck Cancer Promotes Favorable Chemotherapeutic Responses Linked to HypomethylationNSD1 Mutations Promote Hypomethylation and Favorable Outcome
N Bui, JK Huang, A Bojorquez-Gomez, K Licon, KS Sanchez, SN Tang, ...
Molecular cancer therapeutics 17 (7), 1585-1594, 2018
402018
ERCC1 and TS Expression as Prognostic and Predictive Biomarkers in Metastatic Colon Cancer
PF Michel B. Choueiri , John Paul Shen , Andrew M. Gross, Justin K. Huang ...
PLOS ONE, 2015
342015
Genomic landscape of appendiceal neoplasms
CSP Ang, JP Shen, CJ Hardy-Abeloos, JK Huang, JS Ross, VA Miller, ...
JCO Precision Oncology 2, 1-18, 2018
332018
A 150-MHz graphics rendering processor with 256-Mb embedded DRAM
AK Khan, H Magoshi, T Matsumoto, J Fujita, M Furuhashi, M Imai, ...
IEEE Journal of Solid-State Circuits 36 (11), 1775-1784, 2001
312001
Comprehensive Clinical and Molecular Characterization of KRASG12C-Mutant Colorectal Cancer
JT Henry, O Coker, S Chowdhury, JP Shen, VK Morris, A Dasari, ...
JCO Precision Oncology 5, 613-621, 2021
252021
Synthesis of Eupalinilide E, a promoter of human hematopoietic stem and progenitor cell expansion
TC Johnson, MR Chin, T Han, JP Shen, T Rana, D Siegel
Journal of the American Chemical Society 138 (18), 6068-6073, 2016
242016
Phase I/II trial of encorafenib, cetuximab, and nivolumab in patients with microsatellite stable, BRAFV600E metastatic colorectal cancer.
VK Morris, CM Parseghian, M Escano, B Johnson, KPS Raghav, A Dasari, ...
Journal of Clinical Oncology 40 (4_suppl), 12-12, 2022
222022
ARID1A Mutation May Define an Immunologically Active Subgroup in Patients with Microsatellite Stable Colorectal CancerARID1A Mutation in Colorectal Cancer
A Mehrvarz Sarshekeh, J Alshenaifi, J Roszik, GC Manyam, SM Advani, ...
Clinical Cancer Research 27 (6), 1663-1670, 2021
222021
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