Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo KB Johnsen, M Bak, F Melander, MS Thomsen, A Burkhart, PJ Kempen, ... Journal of Controlled Release 295, 237-249, 2019 | 149 | 2019 |
Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles KB Johnsen, M Bak, PJ Kempen, F Melander, A Burkhart, MS Thomsen, ... Theranostics 8 (12), 3416, 2018 | 133 | 2018 |
Genetic incorporation of olefin cross-metathesis reaction tags for protein modification B Bhushan, YA Lin, M Bak, A Phanumartwiwath, N Yang, MK Bilyard, ... Journal of the American Chemical Society 140 (44), 14599-14603, 2018 | 57 | 2018 |
Tumor repolarization by an advanced liposomal drug delivery system provides a potent new approach for chemo-immunotherapy L Ringgaard, F Melander, R Eliasen, JR Henriksen, RI Jølck, TB Engel, ... Science Advances 6 (36), eaba5628, 2020 | 54 | 2020 |
Affinity induced surface functionalization of liposomes using Cu-free click chemistry M Bak, RI Jølck, R Eliasen, TL Andresen Bioconjugate Chemistry 27 (7), 1673-1680, 2016 | 19 | 2016 |
Mechanisms of selective monocyte targeting by liposomes functionalized with a cationic, arginine-rich lipopeptide R Münter, M Bak, E Christensen, PJ Kempen, JB Larsen, K Kristensen, ... Acta Biomaterialia 144, 96-108, 2022 | 10 | 2022 |
Enhancing adoptive cell therapy by T cell loading of SHP2 inhibitor nanocrystals before infusion X Li, HR Halldórsdóttir, S Weller, A Colliander, M Bak, P Kempen, ... ACS nano 16 (7), 10918-10930, 2022 | 6 | 2022 |
Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles. Theranostics. 2018; 8 (12): 3416–36 KB Johnsen, M Bak, PJ Kempen, F Melander, A Burkhart, MS Thomsen, ... Epub 2018/06/23. https://doi. org/10.7150/thno. 25228 PMID: 29930740, 0 | 6 | |
Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles. Theranostics. 2018; 8: 3416–3436 KB Johnsen, M Bak, PJ Kempen, F Melander, A Burkhart, MS Thomsen, ... | 4 | |
Systemic TLR7/8 micelles trigger a novel and potent anti-tumor response by strong recruitment of neutrophils leading to massive tumor cell killing. SS Jensen, E Christensen, MJ Petersen, R Munther, A Hansen, M Bak, ... Journal of Clinical Oncology 40 (16_suppl), 2576-2576, 2022 | 2 | 2022 |
CarboCell combinatorial immunotherapy orchestrates curative anticancer immune activation of the tumor microenvironment S Jensen, E Serrano-Chávez, H Halldórsdóttir, T Engel, J Jørgensen, ... | 1 | 2023 |
An in situ depot for the sustained release of a TLR7/8 agonist in combination with a TGFβ inhibitor promotes anti-tumor immune responses SB Jensen, DE Jæhger, E Serrano-Chávez, HR Halldórsdóttir, TB Engel, ... Nature Communications 15 (1), 7687, 2024 | | 2024 |
HER2-targeted, enzyme-activated liposomes show superior in vivo efficacy in an ovarian cancer model CA Juul, TB Engel, FP Fliedner, L Ringgaard, R Eliasen, F Melander, ... Journal of Controlled Release 371, 288-297, 2024 | | 2024 |
Deciphering the monocyte-targeting mechanisms of PEGylated cationic liposomes by investigating the biomolecular corona R Münter, M Bak, ME Thomsen, L Parhamifar, A Stensballe, JB Simonsen, ... International Journal of Pharmaceutics 657, 124129, 2024 | | 2024 |
1169 Systemic administration of TLR7/8 agonist micelles triggers a potent anti-tumor response mediated by neutrophils as primary effector cells followed by establishment of an … S Jensen, E Christensen, MJ Petersen, A Hansen, M Bak, C Stavnsbjerg, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
611 Exploiting T cells as vehicles of liposomal SHP2i to enhance adoptive cell therapy X Li, H Halldórsdóttir, S Weller, A Colliander, D Jæhger, M Bak, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | | 2021 |
771 Novel lipid nanoparticle vaccine platform for efficient delivery of high-and low-affinity epitopes UJ Björgvinsdóttir, LS Carstensen, A Colliander, DE Jæhger, GC Veiga, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | | 2021 |
Delivery of TLR7 agonists by Deep-Primed™ T cells induces immune activation and improves anti-tumor activity in mice while circumventing systemic toxicity A Boesch, V Rybakin, N Westcott, JY Hwang, K Jørgensen, R Lassen, ... 34th Annual Meeting & Pre-Conference Programs of the Society for …, 2019 | | 2019 |
Potent anti-tumor effect of systemically administered nanoparticles containing a TLR7 agonist in combination with radiotherapy C Stavnsbjerg, E Christensen, RD Münter, A Kjær, S Panina, M Bak, ... Journal for ImmunoTherapy of Cancer 7 (Suppl 1: 283), 9-10, 2019 | | 2019 |
Immunogel-an intratumoral multi-drug sustained release technology that polarizes the tumor microenvironment towards a proinflammatory and immunosupportive state T Engel, JS Jørgensen, L Ringgaard, F Melander, S Jensen, LM Bruun, ... Journal for ImmunoTherapy of Cancer 7 (Suppl. 1), P519, 2019 | | 2019 |