Kyros Kyrou
Kyros Kyrou
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A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae
A Hammond, R Galizi, K Kyrou, A Simoni, C Siniscalchi, D Katsanos, ...
Nature biotechnology 34 (1), 78-83, 2016
A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes
K Kyrou, AM Hammond, R Galizi, N Kranjc, A Burt, AK Beaghton, T Nolan, ...
Nature biotechnology 36 (11), 1062-1066, 2018
The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito
AM Hammond, K Kyrou, M Bruttini, A North, R Galizi, X Karlsson, N Kranjc, ...
PLoS genetics 13 (10), e1007039, 2017
A CRISPR-Cas9 sex-ratio distortion system for genetic control
R Galizi, A Hammond, K Kyrou, C Taxiarchi, F Bernardini, SM O’Loughlin, ...
Scientific reports 6 (1), 31139, 2016
A male-biased sex-distorter gene drive for the human malaria vector Anopheles gambiae
A Simoni, AM Hammond, AK Beaghton, R Galizi, C Taxiarchi, K Kyrou, ...
Nature biotechnology 38 (9), 1054-1060, 2020
Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance
A Hammond, X Karlsson, I Morianou, K Kyrou, A Beaghton, M Gribble, ...
PLoS genetics 17 (1), e1009321, 2021
Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field
A Hammond, P Pollegioni, T Persampieri, A North, R Minuz, A Trusso, ...
Nature Communications 12 (1), 4589, 2021
Natural infection of C. elegans by an oomycete reveals a new pathogen-specific immune response
GA Osman, MK Fasseas, SL Koneru, CL Essmann, K Kyrou, ...
Current Biology 28 (4), 640-648. e5, 2018
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression
C Taxiarchi, A Beaghton, NI Don, K Kyrou, M Gribble, D Shittu, SP Collins, ...
Nature Communications 12 (1), 3977, 2021
High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation
C Taxiarchi, N Kranjc, A Kriezis, K Kyrou, F Bernardini, S Russell, T Nolan, ...
Scientific reports 9 (1), 14841, 2019
Cross-Species Y Chromosome Function Between Malaria Vectors of the Anopheles gambiae Species Complex
F Bernardini, R Galizi, M Wunderlich, C Taxiarchi, N Kranjc, K Kyrou, ...
Genetics 207 (2), 729-740, 2017
Assessing the acoustic behaviour of Anopheles gambiae (s.l.) dsxF mutants: implications for vector control
MP Su, M Georgiades, J Bagi, K Kyrou, A Crisanti, JT Albert
Parasites & Vectors 13, 1-9, 2020
Very massive star winds as sources of the short-lived radioactive isotope 26Al
S Martinet, G Meynet, D Nandal, S Ekström, C Georgy, L Haemmerlé, ...
Astronomy & Astrophysics 664, A181, 2022
Driving down malaria transmission with engineered gene drives
WT Garrood, P Cuber, K Willis, F Bernardini, NM Page, ...
Frontiers in Genetics 13, 891218, 2022
Population suppression of the malaria vector Anopheles gambiae by gene drive technology: A large-cage indoor study bridging the gap between laboratory and field testing
A Hammond, P Pollegioni, T Persampieri, A North, R Minuz, A Trusso, ...
Siniscalchi c, Katsanos d, Gribble M, Baker d, Marois E, Russell S, et al: A cRISPR-cas9 gene drive system targeting female reproduction in the malaria mosquito vector …
A Hammond, R Galizi, K Kyrou, A Simoni
Nat Biotechnol 34, 78-83, 2016
Single-cell profiling of Anopheles gambiae spermatogenesis defines the onset of meiotic silencing and premeiotic overexpression of the X chromosome
N Page, C Taxiarchi, D Tonge, J Kuburic, E Chesters, A Kriezis, K Kyrou, ...
Communications Biology 6 (1), 850, 2023
Targeting sex determination for genetic control of the malaria mosquito
K Kyrou
Imperial College London, 2021
Ανάλυση οσμοδεσμευόμενων πρωτεϊνών που εκφράζονται ειδικά στις ωοθήκες του κουνουπιού της ελονοσίας Anopheles gambiae ως πιθανών στόχων για τη μείωση της γονιμότητας θηλυκών …
Κ Κύρου
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