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Diptesh Sil
Diptesh Sil
Research Instructor
Verified email at unmc.edu - Homepage
Title
Cited by
Cited by
Year
Potential adjuvantic properties of innate immune stimuli
HJ Warshakoon, JD Hood, MR Kimbrell, S Malladi, WY Wu, N Shukla, ...
Human vaccines 5 (6), 381-394, 2009
1132009
Determinants of activity at human Toll-like receptors 7 and 8: quantitative structure–activity relationship (QSAR) of diverse heterocyclic scaffolds
E Yoo, DB Salunke, D Sil, X Guo, ACD Salyer, AR Hermanson, M Kumar, ...
Journal of medicinal chemistry 57 (19), 7955-7970, 2014
782014
Toll-like receptor-8 agonistic activities in C2, C4, and C8 modified thiazolo [4, 5-c] quinolines
HP Kokatla, E Yoo, DB Salunke, D Sil, CF Ng, R Balakrishna, SS Malladi, ...
Organic & biomolecular chemistry 11 (7), 1179-1198, 2013
672013
Exquisite Selectivity for Human Toll-Like Receptor 8 in Substituted Furo[2,3-c]quinolines
HP Kokatla, D Sil, SS Malladi, R Balakrishna, AR Hermanson, LM Fox, ...
Journal of medicinal chemistry 56 (17), 6871-6885, 2013
632013
Structure-based design of human TLR8-specific agonists with augmented potency and adjuvanticity
M Beesu, G Caruso, ACD Salyer, KK Khetani, D Sil, M Weerasinghe, ...
Journal of medicinal chemistry 58 (19), 7833-7849, 2015
572015
Structure‐based design of novel human Toll‐like receptor 8 agonists
HP Kokatla, D Sil, H Tanji, U Ohto, SS Malladi, LM Fox, T Shimizu, ...
ChemMedChem 9 (4), 719-723, 2014
502014
Bound to shock: protection from lethal endotoxemic shock by a novel, nontoxic, alkylpolyamine lipopolysaccharide sequestrant
D Sil, A Shrestha, MR Kimbrell, TB Nguyen, AK Adisechan, R Balakrishna, ...
Antimicrobial agents and chemotherapy 51 (8), 2811-2819, 2007
372007
Synthesis of a highly water-soluble derivative of amphotericin B with attenuated proinflammatory activity
SA Adediran, TP Day, D Sil, MR Kimbrell, HJ Warshakoon, SS Malladi, ...
Molecular pharmaceutics 6 (5), 1582-1590, 2009
252009
Stereoselective alkenylation of a 1,3-disubstituted pyrazol-5-one through ring transformation of 2H-pyran-2-ones
D Sil, R Kumar, A Sharon, PR Maulik, VJ Ram
Tetrahedron letters 46 (22), 3807-3809, 2005
252005
Polycation fluorination improves intraperitoneal siRNA delivery in metastatic pancreatic cancer
Y Hang, S Tang, W Tang, D Větvička, C Zhang, Y Xie, F Yu, A Yu, D Sil, ...
Journal of Controlled Release 333, 139-150, 2021
212021
Imbuing aqueous solubility to amphotericin B and nystatin with a vitamin
TP Day, D Sil, NM Shukla, A Anbanandam, VW Day, SA David
Molecular pharmaceutics 8 (1), 297-301, 2011
202011
Controlling plasma protein binding: structural correlates of interactions of hydrophobic polyamine endotoxin sequestrants with human serum albumin
TB Nguyen, EVK Suresh Kumar, D Sil, SJ Wood, KA Miller, ...
Molecular pharmaceutics 5 (6), 1131-1137, 2008
182008
Intraperitoneal siRNA nanoparticles for augmentation of gemcitabine efficacy in the treatment of pancreatic cancer
S Tang, Y Hang, L Ding, W Tang, A Yu, C Zhang, D Sil, Y Xie, D Oupicky
Molecular pharmaceutics 18 (12), 4448-4458, 2021
152021
An innovative approach to the synthesis of substituted benzaldehydes through carbanion induced ring transformation of suitably functionalized 2H-pyran-2-ones
R Pratap, D Sil, VJ Ram
Tetrahedron letters 45 (29), 5743-5745, 2004
152004
Structure–activity relationships of lipopolysaccharide sequestration in guanylhydrazone-bearing lipopolyamines
W Wu, D Sil, ML Szostak, SS Malladi, HJ Warshakoon, MR Kimbrell, ...
Bioorganic & medicinal chemistry 17 (2), 709-715, 2009
142009
Perfluorocarbon nanoemulsions enhance therapeutic siRNA delivery in the treatment of pulmonary fibrosis
L Ding, S Tang, W Tang, DD Mosley, A Yu, D Sil, S Romanova, KL Bailey, ...
Advanced Science 9 (8), 2103676, 2022
112022
A concise synthesis of highly functionalized α,β-unsaturated γ-butyrolactones through ring contraction of 2H-pyran-2-ones
D Sil, A Sharon, PR Maulik, VJ Ram
Tetrahedron letters 45 (33), 6273-6276, 2004
112004
Biophysical mechanisms of the neutralization of endotoxins by lipopolyamines
D Sil, L Heinbockel, Y Kaconis, M Rössle, P Garidel, T Gutsmann, ...
The Open Biochemistry Journal 7, 82, 2013
92013
Dually active polycation/miRNA nanoparticles for the treatment of fibrosis in alcohol-associated liver disease
C Zhang, Y Hang, W Tang, D Sil, HC Jensen-Smith, RG Bennett, ...
Pharmaceutics 14 (3), 669, 2022
82022
Development of small-molecule endotoxin sequestering agents
SA David, D Sil
Endotoxins: Structure, Function and Recognition, 255-283, 2010
82010
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Articles 1–20