DNA methylation clocks in aging: categories, causes, and consequences AE Field, NA Robertson, T Wang, A Havas, T Ideker, PD Adams Molecular cell 71 (6), 882-895, 2018 | 467 | 2018 |
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... The EMBO journal 38 (5), e100492, 2019 | 376 | 2019 |
Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment T Wang, B Tsui, JF Kreisberg, NA Robertson, AM Gross, MK Yu, H Carter, ... Genome biology 18, 1-11, 2017 | 273 | 2017 |
Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence MG Vizioli, T Liu, KN Miller, NA Robertson, K Gilroy, AB Lagnado, ... Genes & Development 34 (5-6), 428-445, 2020 | 232 | 2020 |
A role for p53 in the adaptation to glutamine starvation through the expression of SLC1A3 M Tajan, AK Hock, J Blagih, NA Robertson, CF Labuschagne, F Kruiswijk, ... Cell metabolism 28 (5), 721-736. e6, 2018 | 200 | 2018 |
Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions JJ Cole, NA Robertson, MI Rather, JP Thomson, T McBryan, D Sproul, ... Genome biology 18 (1), 1-16, 2017 | 174 | 2017 |
A multiscale map of the stem cell state in pancreatic adenocarcinoma NK Lytle, LP Ferguson, N Rajbhandari, K Gilroy, RG Fox, A Deshpande, ... Cell 177 (3), 572-586. e22, 2019 | 133 | 2019 |
Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and … DM Nelson, F Jaber-Hijazi, JJ Cole, NA Robertson, JS Pawlikowski, ... Genome biology 17, 1-20, 2016 | 87 | 2016 |
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects NA Robertson, E Latorre-Crespo, M Terradas-Terradas, J Lemos-Portela, ... Nature medicine 28 (7), 1439-1446, 2022 | 56 | 2022 |
The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection S McFarlane, A Orr, APE Roberts, KL Conn, V Iliev, C Loney, ... PLoS pathogens 15 (3), e1007667, 2019 | 54 | 2019 |
BRD4-mediated repression of p53 is a target for combination therapy in AML AL Latif, A Newcombe, S Li, K Gilroy, NA Robertson, X Lei, HJS Stewart, ... Nature communications 12 (1), 241, 2021 | 47 | 2021 |
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer TDF Costa, T Zhuang, J Lorent, E Turco, H Olofsson, M Masia-Balague, ... Nature Communications 10 (1), 3589, 2019 | 45 | 2019 |
Age-related clonal haemopoiesis is associated with increased epigenetic age NA Robertson, RF Hillary, DL McCartney, M Terradas-Terradas, J Higham, ... Current Biology 29 (16), R786-R787, 2019 | 42 | 2019 |
Purifying stem cell‐derived red blood cells: a high‐throughput label‐free downstream processing strategy based on microfluidic spiral inertial separation and membrane filtration E Guzniczak, O Otto, G Whyte, T Chandra, NA Robertson, N Willoughby, ... Biotechnology and bioengineering 117 (7), 2032-2045, 2020 | 17 | 2020 |
Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health DA Gadd, RF Hillary, DL McCartney, L Shi, A Stolicyn, NA Robertson, ... Nature Communications 13 (1), 4670, 2022 | 13 | 2022 |
Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts JJ Cole, BA Faydaci, D McGuinness, R Shaw, RA Maciewicz, ... BMC Bioinformatics 22 (1), 1-21, 2021 | 13 | 2021 |
Spurious intragenic transcription is a feature of mammalian cellular senescence and tissue aging P Sen, G Donahue, C Li, G Egervari, N Yang, Y Lan, N Robertson, ... Nature aging 3 (4), 402-417, 2023 | 12 | 2023 |
Clonality in haematopoietic stem cell ageing M Terradas-Terradas, NA Robertson, T Chandra, K Kirschner Mechanisms of Ageing and Development 189, 111279, 2020 | 8 | 2020 |
DNMT3B oncogenic activity in human intestinal cancer is not linked to CIMP or BRAFV600E mutation DJ MacKenzie, NA Robertson, I Rather, C Reid, G Sendzikaite, ... Iscience 23 (2), 2020 | 4 | 2020 |
High-Density Domain-Focused CRISPR Screens Reveal Epigenetic Regulators of Hox/Meis Gene Expression in Acute Myeloid Leukemia K Barbosa, A Deshpande, P Xiang, BR Chen, A Brown, N Robertson, ... Blood 136, 2-3, 2020 | 3 | 2020 |