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Holger Franken
Holger Franken
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Year
Tracking cancer drugs in living cells by thermal profiling of the proteome
MM Savitski, FBM Reinhard, H Franken, T Werner, MF Savitski, ...
Science 346 (6205), 1255784, 2014
9832014
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry
H Franken, T Mathieson, D Childs, GMA Sweetman, T Werner, I Tögel, ...
Nature protocols 10 (10), 1567-1593, 2015
5432015
Systematic analysis of protein turnover in primary cells
T Mathieson, H Franken, J Kosinski, N Kurzawa, N Zinn, G Sweetman, ...
Nature communications 9 (1), 689, 2018
3172018
Preanalytical aspects and sample quality assessment in metabolomics studies of human blood
P Yin, A Peter, H Franken, X Zhao, SS Neukamm, L Rosenbaum, M Lucio, ...
Clinical chemistry 59 (5), 833-845, 2013
3022013
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins
FBM Reinhard, D Eberhard, T Werner, H Franken, D Childs, C Doce, ...
Nature methods 12 (12), 1129-1131, 2015
2852015
Multiplexed proteome dynamics profiling reveals mechanisms controlling protein homeostasis
MM Savitski, N Zinn, M Faelth-Savitski, D Poeckel, S Gade, I Becher, ...
Cell 173 (1), 260-274. e25, 2018
2002018
Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver
R Lehmann, H Franken, S Dammeier, L Rosenbaum, K Kantartzis, ...
Diabetes care 36 (8), 2331-2338, 2013
1272013
Identifying drug targets in tissues and whole blood with thermal-shift profiling
J Perrin, T Werner, N Kurzawa, A Rutkowska, DD Childs, M Kalxdorf, ...
Nature Biotechnology 38 (3), 303-308, 2020
1262020
Automated label-free quantification of metabolites from liquid chromatography–mass spectrometry data
E Kenar, H Franken, S Forcisi, K Wörmann, HU Häring, R Lehmann, ...
Molecular & Cellular Proteomics 13 (1), 348-359, 2014
932014
Nonparametric analysis of thermal proteome profiles reveals novel drug-binding proteins
D Childs, K Bach, H Franken, S Anders, N Kurzawa, M Bantscheff, ...
Molecular & Cellular Proteomics 18 (12), 2506-2515, 2019
922019
Activation of the mitogen-activated protein kinase (MAPK) signalling pathway in the liver of mice is related to plasma glucose levels after acute exercise
M Hoene, H Franken, L Fritsche, R Lehmann, AK Pohl, HU Häring, A Zell, ...
Diabetologia 53, 1131-1141, 2010
512010
A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles
N Kurzawa, I Becher, S Sridharan, H Franken, A Mateus, S Anders, ...
Nature communications 11 (1), 5783, 2020
362020
TPP: Analyze thermal proteome profiling (TPP) experiments
D Childs, N Kurzawa, H Franken, C Doce, M Savitski, W Huber
R package version 3 (0), 0, 2023
202023
Wrapper-and ensemble-based feature subset selection methods for biomarker discovery in targeted metabolomics
H Franken, R Lehmann, HU Häring, A Fritsche, N Stefan, A Zell
Pattern Recognition in Bioinformatics: 6th IAPR International Conference …, 2011
92011
Inferring disease-related metabolite dependencies with a Bayesian optimization algorithm
H Franken, A Seitz, R Lehmann, HU Häring, N Stefan, A Zell
Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics …, 2012
62012
Computational analysis of ligand dose range thermal proteome profiles
N Kurzawa, I Becher, S Sridharan, H Franken, A Mateus, S Anders, ...
bioRxiv, 2020.05. 08.083709, 2020
22020
Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo
J Perrin, T Werner, N Kurzawa, DD Childs, M Kalxdorf, A Rutkowska, ...
bioRxiv, 500306, 2018
22018
Metabolomics in diabetes research
K Wörmann, M Lucio, S Forcisi, SS Heinzmann, E Kenar, H Franken, ...
Der Diabetologe 8, 42-48, 2012
12012
A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles (Nov, 10.1038/s41467-020-19529-8, 2020)
N Kurzawa, I Becher, S Sridharan, H Franken, A Mateus, S Anders, ...
NATURE COMMUNICATIONS 12 (1), 2021
2021
Author Correction: A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles
N Kurzawa, I Becher, S Sridharan, H Franken, A Mateus, S Anders, ...
Nature Communications 12, 2021
2021
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