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Hitman G
Hitman G
Centre for Diabetes, Blizard Institute, QMUL
Bekræftet mail på qmul.ac.uk
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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
1958 Birth Cohort Controls Jones Richard W. 18 McArdle Wendy L. 18 Ring ...
Nature 447 (7145), 661-678, 2007
88482007
Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo …
HM Colhoun, DJ Betteridge, PN Durrington, GA Hitman, HAW Neil, ...
The Lancet 364 (9435), 685-696, 2004
51452004
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
TM Frayling, NJ Timpson, MN Weedon, E Zeggini, RM Freathy, ...
Science 316 (5826), 889-894, 2007
50942007
Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials
CT Trialists
The Lancet 376 (9753), 1670-1681, 2010
3670*2010
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
E Zeggini, MN Weedon, CM Lindgren, TM Frayling, KS Elliott, H Lango, ...
Science 316 (5829), 1336-1341, 2007
24662007
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
E Zeggini, LJ Scott, R Saxena, BF Voight, JL Marchini, T Hu, ...
Nature genetics 40 (5), 638-645, 2008
21612008
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
BF Voight, LJ Scott, V Steinthorsdottir, AP Morris, C Dina, RP Welch, ...
Nature genetics 42 (7), 579-589, 2010
20232010
Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes
MF McDermott, I Aksentijevich, J Galon, EM McDermott, BW Ogunkolade, ...
Cell 97 (1), 133-144, 1999
14671999
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ...
Nature genetics 39 (11), 1329-1337, 2007
13522007
Large-scale association studies of variants in genes encoding the pancreatic β-cell KATP channel subunits Kir6. 2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant …
AL Gloyn, MN Weedon, KR Owen, MJ Turner, BA Knight, G Hitman, ...
Diabetes 52 (2), 568-572, 2003
9692003
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls
Nature 464 (7289), 713-720, 2010
8862010
Association of LDL cholesterol, non–HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis
SM Boekholdt, BJ Arsenault, S Mora, TR Pedersen, JC LaRosa, PJ Nestel, ...
Jama 307 (12), 1302-1309, 2012
8742012
Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials
SM Boekholdt, GK Hovingh, S Mora, BJ Arsenault, P Amarenco, ...
Journal of the American College of Cardiology 64 (5), 485-494, 2014
6862014
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
S Nejentsev, JMM Howson, NM Walker, J Szeszko, SF Field, HE Stevens, ...
Nature 450 (7171), 887-892, 2007
6442007
Circulating MMP9, vitamin D and variation in the TIMP‐1 response with VDR genotype: mechanisms for inflammatory damage in chronic disorders?
PM Timms, N Mannan, GA Hitman, K Noonan, PG Mills, ...
Qjm 95 (12), 787-796, 2002
622*2002
Parental origin of sequence variants associated with complex diseases
A Kong, V Steinthorsdottir, G Masson, G Thorleifsson, P Sulem, ...
Nature 462 (7275), 868-874, 2009
6072009
Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis
CT Trialists
The Lancet 371 (9607), 117-125, 2008
6002008
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
Z Dastani, MF Hivert, N Timpson, JRB Perry, X Yuan, RA Scott, ...
PLoS genetics 8 (3), e1002607, 2012
4942012
Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
J Armitage, C Baigent, E Barnes, DJ Betteridge, L Blackwell, M Blazing, ...
The Lancet 393 (10170), 407-415, 2019
4762019
Common variants in WFS1 confer risk of type 2 diabetes
MS Sandhu, MN Weedon, KA Fawcett, J Wasson, SL Debenham, A Daly, ...
Nature genetics 39 (8), 951-953, 2007
4392007
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