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Salerwe Mosebi
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Active-site mutations in the South African human immunodeficiency virus type 1 subtype C protease have a significant impact on clinical inhibitor binding: kinetic and …
S Mosebi, L Morris, HW Dirr, Y Sayed
Journal of virology 82 (22), 11476-11479, 2008
492008
Novel furocoumarins as potential HIV-1 integrase inhibitors
TO Olomola, S Mosebi, R Klein, T Traut-Johnstone, J Coates, R Hewer, ...
Bioorganic chemistry 57, 1-4, 2014
452014
Tertiary interactions stabilise the C-terminal region of human glutathione transferase A1-1: a crystallographic and calorimetric study
DC Kuhnert, Y Sayed, S Mosebi, M Sayed, T Sewell, HW Dirr
Journal of molecular biology 349 (4), 825-838, 2005
422005
Residue 219 impacts on the dynamics of the C-terminal region in glutathione transferase A1-1: implications for stability and catalytic and ligandin functions
S Mosebi, Y Sayed, J Burke, HW Dirr
Biochemistry 42 (51), 15326-15332, 2003
312003
Design, synthesis and biological evaluation of imidazole and oxazole fragments as HIV-1 integrase-LEDGF/p75 disruptors and inhibitors of microbial pathogens
TJ Rashamuse, AT Harrison, S Mosebi, S van Vuuren, EM Coyanis, ...
Bioorganic & Medicinal Chemistry 28 (1), 115210, 2020
242020
Modification of HIV-1 reverse transcriptase and integrase activity by gold (III) complexes in direct biochemical assays
M Mphahlele, M Papathanasopoulos, MA Cinellu, M Coyanis, S Mosebi, ...
Bioorganic & medicinal chemistry 20 (1), 401-407, 2012
202012
Synthesis and evaluation of 3-hydroxy-3-phenylpropanoate ester–AZT conjugates as potential dual-action HIV-1 Integrase and Reverse Transcriptase inhibitors
MH Manyeruke, TO Olomola, S Majumder, S Abrahams, M Isaacs, ...
Bioorganic & Medicinal Chemistry 23 (24), 7521-7528, 2015
172015
Characterization of the binding of 8-anilinonaphthalene sulfonate to rat class Mu GST M1-1
N Kinsley, Y Sayed, S Mosebi, RN Armstrong, HW Dirr
Biophysical chemistry 137 (2-3), 100-104, 2008
172008
The evaluation of statins as potential inhibitors of the LEDGF/p75–HIV‐1 integrase interaction
AT Harrison, FH Kriel, MA Papathanasopoulos, S Mosebi, S Abrahams, ...
Chemical Biology & Drug Design 85 (3), 290-295, 2015
162015
Functional roles of HIV-1 Vpu and CD74: Details and implications of the Vpu–CD74 interaction
DA Le Noury, S Mosebi, MA Papathanasopoulos, R Hewer
Cellular Immunology 298 (1-2), 25-32, 2015
152015
Design, synthesis and biological evaluation of novel 2-(5-aryl-1H-imidazol-1-yl) derivatives as potential inhibitors of the HIV-1 Vpu and host BST-2 protein interaction
TJ Rashamuse, Z Njengele, EM Coyanis, Y Sayed, S Mosebi, ML Bode
European Journal of Medicinal Chemistry 190, 112111, 2020
112020
The effects of temperature on streptavidin-biotin binding using affinity isothermal titration calorimetry
KL Mpye, S Gildenhuys, S Mosebi
AIMS Biophysics 7 (4), 236-247, 2020
102020
A review of the nucleic acid-based lateral flow assay for detection of breast cancer from circulating biomarkers at a point-of-care in low income countries
B Dyan, PP Seele, A Skepu, PS Mdluli, S Mosebi, NRS Sibuyi
Diagnostics 12 (8), 1973, 2022
92022
Molecular Mechanisms of HIV protease inhibitors against HPV-Associated Cervical Cancer: restoration of TP53 tumour suppressor activities
L Makgoo, S Mosebi, Z Mbita
Frontiers in Molecular Biosciences 9, 875208, 2022
92022
Screening of the NIH Clinical Collection for inhibitors of HIV-1 integrase activity
S Abrahams, S Mosebi, MQ Fish, MA Papathanasopoulos, R Hewer
South African Journal of Science 114 (3-4), 1-5, 2018
82018
Expression, purification and characterization of a full-length recombinant HIV-1 Vpu from inclusion bodies
Z Njengele, R Kleynhans, Y Sayed, S Mosebi
Protein Expression and Purification 128, 109-114, 2016
82016
Long noncoding RNAs (lncRNAs) in HIV-mediated carcinogenesis: Role in cell homeostasis, cell survival processes and drug resistance
L Makgoo, S Mosebi, Z Mbita
Non-coding RNA research 7 (3), 184-196, 2022
32022
Active site mutations in the South African HIV-1 subtype C protease impact significantly on clinical inhibitor binding: a kinetic and thermodynamic study
S Mosebi, L Morris, HW Dirr, Y Sayed
J. Virol 82, 11476-11479, 2008
32008
HIV protease hinge region insertions at codon 38 affect enzyme kinetics, conformational stability and dynamics
Z Sheik Ismail, R Worth, S Mosebi, Y Sayed
The Protein Journal 42 (5), 490-501, 2023
22023
Calorimetry to quantify protein-ligand binding
S Mosebi
Appl Calorim 117, 2022
22022
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Articles 1–20