Follow
Alex Fichtenholtz
Alex Fichtenholtz
Computational Biologist, Cure-One
No verified email
Title
Cited by
Cited by
Year
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
GM Frampton, A Fichtenholtz, GA Otto, K Wang, SR Downing, J He, ...
Nature biotechnology 31 (11), 1023-1031, 2013
21622013
Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors
GM Frampton, SM Ali, M Rosenzweig, J Chmielecki, X Lu, TM Bauer, ...
Cancer discovery 5 (8), 850-859, 2015
7332015
Methotrexate‐immobilized poly (ethylene glycol) magnetic nanoparticles for MR imaging and drug delivery
N Kohler, C Sun, A Fichtenholtz, J Gunn, C Fang, M Zhang
Small 2 (6), 785-792, 2006
5222006
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting
J He, O Abdel-Wahab, MK Nahas, K Wang, RK Rampal, AM Intlekofer, ...
Blood, The Journal of the American Society of Hematology 127 (24), 3004-3014, 2016
2802016
Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors. Cancer Discov. 2015; 5: 850–859 …
GM Frampton, SM Ali, M Rosenzweig, J Chmielecki, X Lu, TM Bauer, ...
Go to original source... Go to PubMed, 2015
1152015
Noninstrumented nucleic acid amplification assay
BH Weigl, G Domingo, J Gerlach, D Tang, D Harvey, N Talwar, ...
Microfluidics, BioMEMS, and Medical Microsystems VI 6886, 42-53, 2008
92008
Identification of actionable genomic alterations in hematologic malignancies by a clinical next generation sequencing-based assay
D Lipson, MK Nahas, GA Otto, R Yelensky, O Abdel-Wahab, K Wang, ...
Blood, The Journal of the American Society of Hematology 122 (21), 230-230, 2013
52013
Development and analytical validation of a clinical next generation sequencing-based assay for hematolymphoid malignancies
J He, D Lipson, M Nahas, GA Otto, K Wang, KM Knapp, KW Brennan, ...
Proceedings of the American Association for Cancer Research Annual Meeting, 5-9, 2014
42014
Activation of MET via diverse exon 14 skipping mutations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors
GM Frampton, S Ali, J Chmielecki, M Rosenzweig, T Brennan, Z Chalmers, ...
Cancer Research 75 (15_Supplement), 1118-1118, 2015
12015
Bringing next generation sequencing (NGS) to the clinic: Analytical validation of a comprehensive NGS-based cancer gene test.
R Yelensky, GM Frampton, A Fichtenholtz, S Downing, J He, F Juhn, ...
Cancer Research 73 (8_Supplement), 2279-2279, 2013
12013
Chemically-heated non-instrumented nucleic-acid amplification assay platform
B Weigl, GJ Domingo, J Gerlach, J Wilmoth, D Tang, D Harvey, N Talwar, ...
40th Annual American Association of Clinical Chemistry Oak Ridge Conference, 2008
12008
COMPREHENSIVE GENOMIC ANALYSIS OF YOUNG ADULT GLIOBLASTOMAS REVEALS FOUR SUBCLASSES WITH DISTINCT DRIVER EVENTS
S Ramkissoon, M Chang, A Johnson, L Gay, J Chmielecki, J Elvin, J Suh, ...
NEURO-ONCOLOGY 18, 113-114, 2016
2016
Unsupervised latent class analysis of adult glioma variant profiles reveals biologically and clinically relevant subclasses
M Chang, S Ramkissoon, H Bokhari, A Fichtenholtz, S Ali, JS Ross, ...
Annals of Oncology 27, vi545, 2016
2016
Abstract LB-328: Subtypes of urothelial carcinoma of the urinary bladder defined by genomic alteration combinations predict clinical characteristics
A Khan, A Fichtenholtz, J Ross, G Frampton, E Neumann, SM Ali, ...
Cancer Research 76 (14_Supplement), LB-328-LB-328, 2016
2016
Subtypes of urothelial carcinoma of the urinary bladder defined by genomic alteration combinations predict clinical characteristics
A Khan, A Fichtenholtz, J Ross, G Frampton, E Neumann, SM Ali, ...
CANCER RESEARCH 76, 2016
2016
Latent class analysis of bladder urothelial carcinoma to reveal sub-classes defined by alterations to chromatin and signal transduction networks.
A Fichtenholtz, A Khan, JS Ross, SM Ali, VA Miller, PJ Stephens, ...
Journal of Clinical Oncology 34 (2_suppl), 469-469, 2016
2016
PREDICTING SIGNIFICANCE OF UNKNOWN VARIANTS IN GLIAL TUMORS THROUGH SUB-CLASS ENRICHMENT
AM Fichtenholtz, ND Camarda, EK Neumann
Biocomputing 2016: Proceedings of the Pacific Symposium, 297-308, 2016
2016
The complex genomic landscape of glial tumors reveals distinct subclasses and potential therapeutic targets associated with clinical responses to targeted inhibitors
J Chmielecki, ME Goldberg, A Fichtenholtz, J Elvin, GM Frampton, SM Ali, ...
Cancer Research 75 (15_Supplement), 4667-4667, 2015
2015
Comprehensive Genomic Profiling of Brain Glioblastoma Reveals Frequent Clinically Relevant Genomic Alterations
Z Chalmers, S Ali, J Elvin, D Lipson, K Wang, R Yelensky, J Chmielecki, ...
LABORATORY INVESTIGATION 95, 429A-429A, 2015
2015
Development and validation of a clinical next generation sequencing-based assay for hematologic malignancies
D Lipson, MK Nahas, GA Otto, J He, K Wang, KM Knapp, KW Brennan, ...
Cancer Research 74 (19_Supplement), 3570-3570, 2014
2014
The system can't perform the operation now. Try again later.
Articles 1–20