| Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016 | 3841 | 2016 |
| SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ... Cell 181 (5), 1016-1035. e19, 2020 | 2350 | 2020 |
| Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput TM Gierahn, MH Wadsworth, TK Hughes, BD Bryson, A Butler, R Satija, ... Nature methods 14 (4), 395-398, 2017 | 850 | 2017 |
| Single-cell RNA-seq reveals AML hierarchies relevant to disease progression and immunity P van Galen, V Hovestadt, MH Wadsworth II, TK Hughes, GK Griffin, ... Cell 176 (6), 1265-1281. e24, 2019 | 738 | 2019 |
| Systematic comparison of single-cell and single-nucleus RNA-sequencing methods J Ding, X Adiconis, SK Simmons, MS Kowalczyk, CC Hession, ... Nature biotechnology 38 (6), 737-746, 2020 | 608 | 2020 |
| Prevention of tuberculosis in macaques after intravenous BCG immunization PA Darrah, JJ Zeppa, P Maiello, JA Hackney, MH Wadsworth, TK Hughes, ... Nature 577 (7788), 95-102, 2020 | 466 | 2020 |
| Allergic inflammatory memory in human respiratory epithelial progenitor cells J Ordovas-Montanes, DF Dwyer, SK Nyquist, KM Buchheit, M Vukovic, ... Nature 560 (7720), 649-654, 2018 | 421 | 2018 |
| Identification of multiple genetic susceptibility loci in Takayasu arteritis G Saruhan-Direskeneli, T Hughes, K Aksu, G Keser, P Coit, SZ Aydin, ... The American Journal of Human Genetics 93 (2), 298-305, 2013 | 198 | 2013 |
| Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients R Webb, JA Kelly, EC Somers, T Hughes, KM Kaufman, E Sanchez, ... Annals of the rheumatic diseases 70 (1), 151-156, 2011 | 194 | 2011 |
| Genome‐wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome N Altorok, P Coit, T Hughes, KA Koelsch, DU Stone, A Rasmussen, ... Arthritis & rheumatology 66 (3), 731-739, 2014 | 181 | 2014 |
| Second-strand synthesis-based massively parallel scRNA-seq reveals cellular states and molecular features of human inflammatory skin pathologies TK Hughes, MH Wadsworth, TM Gierahn, T Do, D Weiss, PR Andrade, ... Immunity 53 (4), 878-894. e7, 2020 | 176 | 2020 |
| Identification of multiple independent susceptibility loci in the HLA region in Behcet's disease T Hughes, P Coit, A Adler, V Yilmaz, K Aksu, N Düzgün, G Keser, A Cefle, ... Nature genetics 45 (3), 319-324, 2013 | 162 | 2013 |
| Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups KM Kaufman, J Zhao, JA Kelly, T Hughes, A Adler, E Sanchez, JO Ojwang, ... Annals of the rheumatic diseases 72 (3), 437-444, 2013 | 119 | 2013 |
| Systematic comparative analysis of single cell RNA-sequencing methods J Ding, X Adiconis, SK Simmons, MS Kowalczyk, CC Hession, ... BioRxiv, 632216, 2019 | 110 | 2019 |
| Analysis of autosomal genes reveals gene–sex interactions and higher total genetic risk in men with systemic lupus erythematosus T Hughes, A Adler, JT Merrill, JA Kelly, KM Kaufman, A Williams, ... Annals of the rheumatic diseases 71 (5), 694-699, 2012 | 107 | 2012 |
| Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control HP Gideon, TK Hughes, CN Tzouanas, MH Wadsworth, AA Tu, ... Immunity 55 (5), 827-846. e10, 2022 | 99 | 2022 |
| Analysis of the effectiveness of the Ad26. COV2. S adenoviral vector vaccine for preventing COVID-19 J Corchado-Garcia, D Zemmour, T Hughes, H Bandi, T Cristea-Platon, ... JAMA network open 4 (11), e2132540-e2132540, 2021 | 98 | 2021 |
| Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation DF Dwyer, J Ordovas-Montanes, SJ Allon, KM Buchheit, M Vukovic, ... Science immunology 6 (56), eabb7221, 2021 | 97 | 2021 |
| Epigenome‐wide scan identifies a treatment‐responsive pattern of altered DNA methylation among cytoskeletal remodeling genes in monocytes and CD4+ T cells from patients with … T Hughes, F Ture‐Ozdemir, F Alibaz‐Oner, P Coit, H Direskeneli, ... Arthritis & rheumatology 66 (6), 1648-1658, 2014 | 87 | 2014 |
| Sex-specific differences in the relationship between genetic susceptibility, T cell DNA demethylation and lupus flare severity AH Sawalha, L Wang, A Nadig, EC Somers, WJ McCune, T Hughes, ... Journal of autoimmunity 38 (2-3), J216-J222, 2012 | 80 | 2012 |
