Maria L. Simões, PhD
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Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer
VM Arlt, M Stiborová, J vom Brocke, ML Simoes, GM Lord, JL Nortier, ...
Carcinogenesis 28 (11), 2253-2261, 2007
CRISPR/Cas9 -mediated gene knockout of Anopheles gambiae FREP1 suppresses malaria parasite infection
Y Dong, ML Simões, E Marois, G Dimopoulos
PLoS pathogens 14 (3), e1006898, 2018
Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression
J Yang, O Staples, LW Thomas, T Briston, M Robson, E Poon, ML Simões, ...
The Journal of clinical investigation 122 (2), 600-611, 2012
A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration
GK Wilson, CL Brimacombe, IA Rowe, GM Reynolds, NF Fletcher, ...
Journal of hepatology 56 (4), 803-809, 2012
Mosquito gut antiparasitic and antiviral immunity
RG Saraiva, S Kang, ML Simoes, YI Anglero-Rodriguez, G Dimopoulos
Developmental & Comparative Immunology 64, 53-64, 2016
Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53
ML Simões, SL Hockley, T Schwerdtle, GG da Costa, HH Schmeiser, ...
Toxicology and applied pharmacology 232 (1), 86-98, 2008
Prospects and pitfalls: next-generation tools to control mosquito-transmitted disease
EP Caragata, S Dong, Y Dong, ML Simões, CV Tikhe, G Dimopoulos
Annual review of microbiology 74, 455-475, 2020
Diverse host and restriction factors regulate mosquito–pathogen interactions
ML Simões, EP Caragata, G Dimopoulos
Trends in parasitology 34 (7), 603-616, 2018
Immune Regulation of Plasmodium Is Anopheles Species Specific and Infection Intensity Dependent
ML Sim § es, G Mlambo, A Tripathi, Y Dong, G Dimopoulos
MBio 8 (5), 10.1128/mbio. 01631-17, 2017
Versatile transgenic multistage effector-gene combinations for Plasmodium falciparum suppression in Anopheles
Y Dong, ML Simões, G Dimopoulos
Science Advances 6 (20), eaay5898, 2020
The Anopheles FBN9 immune factor mediates Plasmodium species-specific defense through transgenic fat body expression
ML Simões, Y Dong, A Hammond, A Hall, A Crisanti, T Nolan, ...
Developmental & Comparative Immunology 67, 257-265, 2017
Mosquito transgenesis for malaria control
S Dong, Y Dong, ML Simões, G Dimopoulos
Trends in parasitology 38 (1), 54-66, 2022
Additional Feeding Reveals Differences in Immune Recognition and Growth of Plasmodium Parasites in the Mosquito Host
H Kwon, ML Simões, RA Reynolds, G Dimopoulos, RC Smith
Msphere 6 (2), 2021
Broad spectrum immunomodulatory effects of Anopheles gambiae microRNAs and their use for transgenic suppression of Plasmodium
S Dong, X Fu, Y Dong, ML Simões, J Zhu, G Dimopoulos
PLoS pathogens 16 (4), e1008453, 2020
New rapid one-step PCR diagnostic assay for Plasmodium falciparum infective mosquitoes
M Kefi, K Mavridis, ML Simões, G Dimopoulos, I Siden-Kiamos, J Vontas
Scientific reports 8 (1), 1462, 2018
Hemozoin activates the innate immune system and reduces Plasmodium berghei infection in Anopheles gambiae
ML Simões, L Gonçalves, H Silveira
Parasites & vectors 8, 1-14, 2015
C-type lectin 4 regulates broad-spectrum melanization-based refractoriness to malaria parasites
ML Simões, Y Dong, G Mlambo, G Dimopoulos
PLoS biology 20 (1), e3001515, 2022
A mosquito mediator of parasite-induced immune priming
ML Simões, G Dimopoulos
Trends in parasitology 31 (9), 402-404, 2015
Immune pathways in Anopheles gambiae
ML Simões, R Chandrasekar
Short views on insect biochemistry and molecular biolody, 253-270, 2014
Immune regulation of Plasmodium is Anopheles species specific and infection intensity dependent. mBio 8: e01631-17
ML Simões, G Mlambo, A Tripathi, Y Dong, G Dimopoulos
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