|Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort|
DE Shaw, AR Sousa, SJ Fowler, LJ Fleming, G Roberts, J Corfield, ...
European Respiratory Journal 46 (5), 1308-1321, 2015
|Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI)|
EH Bel, A Sousa, L Fleming, A Bush, KF Chung, J Versnel, AH Wagener, ...
Thorax 66 (10), 910-917, 2011
|Pediatric severe asthma is characterized by eosinophilia and remodeling without TH2 cytokines|
CJ Bossley, L Fleming, A Gupta, N Regamey, J Frith, T Oates, L Tsartsali, ...
Journal of Allergy and Clinical Immunology 129 (4), 974-982. e13, 2012
|The importance of nurse-led home visits in the assessment of children with problematic asthma|
M Bracken, L Fleming, P Hall, N Van Stiphout, C Bossley, E Biggart, ...
Archives of disease in childhood 94 (10), 780-784, 2009
|GINA 2019: a fundamental change in asthma management: Treatment of asthma with short-acting bronchodilators alone is no longer recommended for adults and adolescents|
HK Reddel, JM FitzGerald, ED Bateman, LB Bacharier, A Becker, ...
European Respiratory Journal 53 (6), 2019
|U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics|
D Lefaudeux, B De Meulder, MJ Loza, N Peffer, A Rowe, F Baribaud, ...
Journal of Allergy and Clinical Immunology 139 (6), 1797-1807, 2017
|Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data|
L San Román, BK Menon, J Blasco, M Hernández-Pérez, A Dávalos, ...
The Lancet Neurology 17 (10), 895-904, 2018
|Increased airway smooth muscle mass in children with asthma, cystic fibrosis, and non-cystic fibrosis bronchiectasis|
N Regamey, M Ochs, TN Hilliard, C Mühlfeld, N Cornish, L Fleming, ...
American journal of respiratory and critical care medicine 177 (8), 837-843, 2008
|Measurement of bronchial and alveolar nitric oxide production in normal children and children with asthma|
E Paraskakis, C Brindicci, L Fleming, R Krol, SA Kharitonov, NM Wilson, ...
American journal of respiratory and critical care medicine 174 (3), 260-267, 2006
|Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33|
S Castanhinha, R Sherburn, S Walker, A Gupta, CJ Bossley, J Buckley, ...
Journal of Allergy and Clinical Immunology 136 (2), 312-322. e7, 2015
|Sputum inflammatory phenotypes are not stable in children with asthma|
L Fleming, L Tsartsali, N Wilson, N Regamey, A Bush
Thorax 67 (8), 675-681, 2012
|The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts|
L Fleming, C Murray, AT Bansal, S Hashimoto, H Bisgaard, A Bush, ...
European Respiratory Journal 46 (5), 1322-1333, 2015
|Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis …|
BCV Campbell, CBLM Majoie, GW Albers, BK Menon, N Yassi, G Sharma, ...
The Lancet Neurology 18 (1), 46-55, 2019
|Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta …|
BCV Campbell, WH Van Zwam, M Goyal, BK Menon, DWJ Dippel, ...
The Lancet Neurology 17 (1), 47-53, 2018
|Type 2 innate lymphoid cells in induced sputum from children with severe asthma|
P Nagakumar, L Denney, L Fleming, A Bush, CM Lloyd, S Saglani
Journal of Allergy and Clinical Immunology 137 (2), 624-626. e6, 2016
|A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED|
CHS Kuo, S Pavlidis, M Loza, F Baribaud, A Rowe, I Pandis, U Hoda, ...
American journal of respiratory and critical care medicine 195 (4), 443-455, 2017
|Use of sputum eosinophil counts to guide management in children with severe asthma|
L Fleming, N Wilson, N Regamey, A Bush
Thorax 67 (3), 193-198, 2012
|Blood eosinophil counts rarely reflect airway eosinophilia in children with severe asthma|
N Ullmann, CJ Bossley, L Fleming, M Silvestri, A Bush, S Saglani
Allergy 68 (3), 402-406, 2013
|Severe asthma in children|
A Bush, L Fleming, S Saglani
Respirology 22 (5), 886-897, 2017
|Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation|
Z Jevnikar, J Östling, E Ax, J Calvén, K Thörn, E Israelsson, L Öberg, ...
Journal of allergy and clinical immunology 143 (2), 577-590, 2019