| The energetic basis of specificity in the Eco RI endonuclease—DNA interaction DR Lesser, MR Kurpiewski, L Jen-Jacobson Science 250 (4982), 776-786, 1990 | 421 | 1990 |
| Kinked DNA in crystalline complex with EcoRI endonuclease CA Frederick, J Grable, M Melia, C Samudzi, L Jen-Jacobson, BC Wang, ... Nature 309 (5966), 327-331, 1984 | 347 | 1984 |
| Structural and thermodynamic strategies for site-specific DNA binding proteins L Jen-Jacobson, LE Engler, LA Jacobson Structure 8 (10), 1015-1023, 2000 | 317 | 2000 |
| Protein—DNA recognition complexes: Conservation of structure and binding energy in the transition state L Jen‐Jacobson Biopolymers: Original Research on Biomolecules 44 (2), 153-180, 1997 | 262 | 1997 |
| Coordinate ion pair formation between EcoRI endonuclease and DNA. L Jen-Jacobson, M Kurpiewski, D Lesser, J Grable, HW Boyer, ... Journal of Biological Chemistry 258 (23), 14638-14646, 1983 | 137 | 1983 |
| Specific binding by EcoRV endonuclease to its DNA recognition site GATATC LE Engler, KK Welch, L Jen-Jacobson Journal of molecular biology 269 (1), 82-101, 1997 | 134 | 1997 |
| Facilitated distortion of the DNA site enhances EcoRI endonuclease-DNA recognition. DR Lesser, MR Kurpiewski, T Waters, BA Connolly, L Jen-Jacobson Proceedings of the National Academy of Sciences 90 (16), 7548-7552, 1993 | 127 | 1993 |
| The energetics of the interaction of BamHI endonuclease with its recognition site GGATCC LE Engler, P Sapienza, LF Dorner, R Kucera, I Schildkraut, ... Journal of molecular biology 307 (2), 619-636, 2001 | 101 | 2001 |
| The enfolding arms of EcoRI endonuclease: role in DNA binding and cleavage L Jen-Jacobson, D Lesser, M Kurpiewski Cell 45 (4), 619-629, 1986 | 98 | 1986 |
| Single-molecule sequence detection via microfluidic planar extensional flow at a stagnation point R Dylla-Spears, JE Townsend, L Jen-Jacobson, LL Sohn, SJ Muller Lab on a Chip 10 (12), 1543-1549, 2010 | 93 | 2010 |
| Thermodynamic parameters of specific and nonspecific protein-DNA binding L Jen-Jacobson, LE Engler, JT Ames, MR Kurpiewski, A Grigorescu Supramolecular Chemistry 12 (2), 143-160, 2000 | 91 | 2000 |
| ESR spectroscopy identifies inhibitory Cu2+ sites in a DNA-modifying enzyme to reveal determinants of catalytic specificity Z Yang, MR Kurpiewski, M Ji, JE Townsend, P Mehta, L Jen-Jacobson, ... Proceedings of the National Academy of Sciences 109 (17), E993-E1000, 2012 | 85 | 2012 |
| Stereoselective interaction with chiral phosphorothioates at the central DNA kink of the EcoRI endonuclease-GAATTC complex. DR Lesser, A Grajkowski, MR Kurpiewski, M Koziolkiewicz, WJ Stec, ... Journal of Biological Chemistry 267 (34), 24810-24818, 1992 | 77 | 1992 |
| " Ultraviolet footprinting" accurately maps sequence-specific contacts and DNA kinking in the EcoRI endonuclease-DNA complex. MM Becker, D Lesser, M Kurpiewski, A Baranger, L Jen-Jacobson Proceedings of the National Academy of Sciences 85 (17), 6247-6251, 1988 | 73 | 1988 |
| Mechanisms of coupling between DNA recognition specificity and catalysis in EcoRI endonuclease MR Kurpiewski, LE Engler, LA Wozniak, A Kobylanska, M Koziolkiewicz, ... Structure 12 (10), 1775-1788, 2004 | 70 | 2004 |
| [14] Structural-perturbation approaches to thermodynamics of site-specific protein—DNA interactions L Jen-Jacobson Methods in enzymology 259, 305-344, 1995 | 60 | 1995 |
| Structural adaptations in the interaction of EcoRI endonuclease with methylated GAATTC sites. L Jen‐Jacobson, LE Engler, DR Lesser, MR Kurpiewski, C Yee, ... The EMBO Journal 15 (11), 2870-2882, 1996 | 57 | 1996 |
| Electron spin resonance shows common structural features for different classes of EcoRI-DNA complexes KM Stone, JE Townsend, J Sarver, PJ Sapienza, S Saxena, ... Angewandte Chemie (International ed. in English) 47 (52), 10192, 2008 | 54 | 2008 |
| Recognition of the pro-mutagenic base uracil by family B DNA polymerases from archaea G Shuttleworth, MJ Fogg, MR Kurpiewski, L Jen-Jacobson, BA Connolly Journal of molecular biology 337 (3), 621-634, 2004 | 52 | 2004 |
| Proteases of the nematode Caenorhabditis elegans GJ Sarkis, MR Kurpiewski, JD Ashcom, L Jen-Jacobson, LA Jacobson Archives of biochemistry and biophysics 261 (1), 80-90, 1988 | 44 | 1988 |
