|Calcium-channel number critically influences synaptic strength and plasticity at the active zone|
J Sheng, L He, H Zheng, L Xue, F Luo, W Shin, T Sun, T Kuner, DT Yue, ...
Nature neuroscience 15 (7), 998, 2012
|Improving the in silico assessment of proarrhythmia risk by combining hERG (Human Ether-à-go-go-Related Gene) channel–drug binding kinetics and multichannel pharmacology|
Z Li, S Dutta, J Sheng, PN Tran, W Wu, K Chang, T Mdluli, DG Strauss, ...
Circulation: Arrhythmia and Electrophysiology 10 (2), e004628, 2017
|Apomorphine-induced activation of dopamine receptors modulates FGF-2 expression in astrocytic cultures and promotes survival of dopaminergic neurons|
A Li, H Guo, X Luo, J Sheng, S Yang, Y Yin, J Zhou, J Zhou, A Li, H Guo, ...
The FASEB journal 20 (8), 1263-1265, 2006
|Cystatin C prevents degeneration of rat nigral dopaminergic neurons: in vitro and in vivo studies|
L Xu, J Sheng, Z Tang, X Wu, Y Yu, H Guo, Y Shen, C Zhou, L Paraoan, ...
Neurobiology of disease 18 (1), 152-165, 2005
|Optimization of an in silico cardiac cell model for proarrhythmia risk assessment|
S Dutta, KC Chang, KA Beattie, J Sheng, PN Tran, WW Wu, M Wu, ...
Frontiers in physiology 8, 616, 2017
|Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles|
HC Chiang, W Shin, WD Zhao, E Hamid, J Sheng, M Baydyuk, PJ Wen, ...
Nature communications 5 (1), 1-17, 2014
|Actin is crucial for all kinetically distinguishable forms of endocytosis at synapses|
XS Wu, SH Lee, J Sheng, Z Zhang, WD Zhao, D Wang, Y Jin, P Charnay, ...
Neuron 92 (5), 1020-1035, 2016
|Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the CiPA Initiative|
Z Li, BJ Ridder, X Han, WW Wu, J Sheng, PN Tran, M Wu, A Randolph, ...
Clinical Pharmacology & Therapeutics 105 (2), 466-475, 2019
|A temperature-dependent in silico model of the human ether-a-go-go-related (hERG) gene channel|
Z Li, S Dutta, J Sheng, PN Tran, W Wu, T Colatsky
Journal of pharmacological and toxicological methods 81, 233-239, 2016
|Bystin as a novel marker for reactive astrocytes in the adult rat brain following injury|
J Sheng, S Yang, L Xu, C Wu, X Wu, A Li, Y Yu, H Ni, M Fukuda, J Zhou
European Journal of Neuroscience 20 (4), 873-884, 2004
|Uncertainty quantification reveals the importance of data variability and experimental design considerations for in silico proarrhythmia risk assessment|
KC Chang, S Dutta, GR Mirams, KA Beattie, J Sheng, PN Tran, M Wu, ...
Frontiers in physiology 8, 917, 2017
|α-Synuclein mutation inhibits endocytosis at mammalian central nerve terminals|
J Xu, XS Wu, J Sheng, Z Zhang, HY Yue, L Sun, C Sgobio, X Lin, S Peng, ...
Journal of Neuroscience 36 (16), 4408-4414, 2016
|Voltage-Dependent Calcium Channels at the Plasma Membrane, but Not Vesicular Channels, Couple Exocytosis to Endocytosis|
L Xue, Z Zhang, BD McNeil, F Luo, XS Wu, J Sheng, W Shin, LG Wu
Cell Reports, 2012
|Most vesicles in a central nerve terminal participate in recycling|
L Xue, J Sheng, XS Wu, W Wu, F Luo, W Shin, HC Chiang, LG Wu
Journal of Neuroscience 33 (20), 8820-8826, 2013
|Bystin-like protein is upregulated in hepatocellular carcinoma and required for nucleologenesis in cancer cell proliferation|
H Wang, W Xiao, Q Zhou, Y Chen, S Yang, J Sheng, Y Yin, J Fan, J Zhou
Cell research 19 (10), 1150-1164, 2009
|Characterization of loperamide-mediated block of hERG channels at physiological temperature and its proarrhythmia propensity|
J Sheng, PN Tran, Z Li, S Dutta, K Chang, T Colatsky, WW Wu
Journal of pharmacological and toxicological methods 88, 109-122, 2017
|Expression of trophinin and bystin identifies distinct cell types in the germinal zones of adult rat brain|
L Ma, M Yin, X Wu, C Wu, S Yang, J Sheng, H Ni, MN Fukuda, J Zhou
European Journal of Neuroscience 23 (9), 2265-2276, 2006
|Cysteine string protein α: a new role in vesicle recycling|
J Sheng, LG Wu
Neuron 74 (1), 6-8, 2012
|Plasticizer interaction with the heart: chemicals used in plastic medical devices can interfere with cardiac electrophysiology|
R Jaimes III, D McCullough, B Siegel, L Swift, D McInerney, J Hiebert, ...
Circulation: Arrhythmia and Electrophysiology 12 (7), e007294, 2019
|A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm|
BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ...
Toxicology and Applied Pharmacology, 114961, 2020