Reverse engineering of regulatory networks in human B cells K Basso, AA Margolin, G Stolovitzky, U Klein, R Dalla-Favera, A Califano Nature genetics 37 (4), 382-390, 2005 | 1672 | 2005 |
Human Immunoglobulin (Ig)M+IgD+ Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes … U Klein, K Rajewsky, R Küppers The Journal of experimental medicine 188 (9), 1679-1689, 1998 | 1464 | 1998 |
Dynamics of B cells in germinal centres NS De Silva, U Klein Nature reviews immunology 15 (3), 137-148, 2015 | 1272 | 2015 |
Germinal centres: role in B-cell physiology and malignancy U Klein, R Dalla-Favera Nature Reviews Immunology 8 (1), 22-33, 2008 | 1245 | 2008 |
Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells U Klein, Y Tu, GA Stolovitzky, M Mattioli, G Cattoretti, H Husson, ... The Journal of experimental medicine 194 (11), 1625-1638, 2001 | 1230 | 2001 |
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses YE Zheng, A Chaudhry, A Kas, P DeRoos, JM Kim, TT Chu, L Corcoran, ... Nature 458 (7236), 351-356, 2009 | 1121 | 2009 |
The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia U Klein, M Lia, M Crespo, R Siegel, Q Shen, T Mo, A Ambesi-Impiombato, ... Cancer cell 17 (1), 28-40, 2010 | 1059 | 2010 |
Cellular origin of human B-cell lymphomas R Küppers, ULF Klein, ML Hansmann, K Rajewsky New England Journal of Medicine 341 (20), 1520-1529, 1999 | 983 | 1999 |
Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination U Klein, S Casola, G Cattoretti, Q Shen, M Lia, T Mo, T Ludwig, ... Nature immunology 7 (7), 773-782, 2006 | 952 | 2006 |
An essential role for the IL-2 receptor in Treg cell function T Chinen, AK Kannan, AG Levine, X Fan, U Klein, Y Zheng, G Gasteiger, ... Nature immunology 17 (11), 1322-1333, 2016 | 916 | 2016 |
BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci L Pasqualucci, A Migliazza, N Fracchiolla, C William, A Neri, L Baldini, ... Proceedings of the National Academy of Sciences 95 (20), 11816-11821, 1998 | 631 | 1998 |
Transcriptional control of adipose lipid handling by IRF4 J Eguchi, X Wang, S Yu, EE Kershaw, PC Chiu, J Dushay, JL Estall, ... Cell metabolism 13 (3), 249-259, 2011 | 599 | 2011 |
Transcriptional analysis of the B cell germinal center reaction U Klein, Y Tu, GA Stolovitzky, JL Keller, J Haddad Jr, V Miljkovic, ... Proceedings of the National Academy of Sciences 100 (5), 2639-2644, 2003 | 541 | 2003 |
Loss of the B-lineage–specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma I Schwering, A Bräuninger, U Klein, B Jungnickel, M Tinguely, V Diehl, ... Blood, The Journal of the American Society of Hematology 101 (4), 1505-1512, 2003 | 511 | 2003 |
Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4 K Ochiai, M Maienschein-Cline, G Simonetti, J Chen, R Rosenthal, ... Immunity 38 (5), 918-929, 2013 | 498 | 2013 |
Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease T Goossens, U Klein, R Küppers Proceedings of the National Academy of Sciences 95 (5), 2463-2468, 1998 | 446 | 1998 |
Somatic hypermutation in normal and transformed human B cells U Klien, T Goasens, M Fischer, H Kanzler, A Braeuninger, K Rajewsky, ... Immunological reviews 162 (1), 261-280, 1998 | 439 | 1998 |
Evidence for a large compartment of IgM-expressing memory B cells in humans U Klein, R Küppers, K Rajewsky Blood, The Journal of the American Society of Hematology 89 (4), 1288-1298, 1997 | 396 | 1997 |
Quantitative noise analysis for gene expression microarray experiments Y Tu, G Stolovitzky, U Klein Proceedings of the National Academy of Sciences 99 (22), 14031-14036, 2002 | 354 | 2002 |
Identification of Hodgkin and Reed-Sternberg cell-specific genes by gene expression profiling R Küppers, U Klein, I Schwering, V Distler, A Bräuninger, G Cattoretti, ... The Journal of clinical investigation 111 (4), 529-537, 2003 | 343 | 2003 |