Ulf Klein
Ulf Klein
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Reverse engineering of regulatory networks in human B cells
K Basso, AA Margolin, G Stolovitzky, U Klein, R Dalla-Favera, A Califano
Nature genetics 37 (4), 382-390, 2005
Human Immunoglobulin (Ig)M+IgD+ Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes …
U Klein, K Rajewsky, R Küppers
The Journal of experimental medicine 188 (9), 1679-1689, 1998
Germinal centres: role in B-cell physiology and malignancy
U Klein, R Dalla-Favera
Nature Reviews Immunology 8 (1), 22-33, 2008
Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells
U Klein, Y Tu, GA Stolovitzky, M Mattioli, G Cattoretti, H Husson, ...
The Journal of experimental medicine 194 (11), 1625-1638, 2001
Dynamics of B cells in germinal centres
NS De Silva, U Klein
Nature reviews immunology 15 (3), 137-148, 2015
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
YE Zheng, A Chaudhry, A Kas, P DeRoos, JM Kim, TT Chu, L Corcoran, ...
Nature 458 (7236), 351-356, 2009
The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia
U Klein, M Lia, M Crespo, R Siegel, Q Shen, T Mo, A Ambesi-Impiombato, ...
Cancer cell 17 (1), 28-40, 2010
Cellular origin of human B-cell lymphomas
R Küppers, ULF Klein, ML Hansmann, K Rajewsky
New England Journal of Medicine 341 (20), 1520-1529, 1999
Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination
U Klein, S Casola, G Cattoretti, Q Shen, M Lia, T Mo, T Ludwig, ...
Nature immunology 7 (7), 773-782, 2006
An essential role for the IL-2 receptor in Treg cell function
T Chinen, AK Kannan, AG Levine, X Fan, U Klein, Y Zheng, G Gasteiger, ...
Nature immunology 17 (11), 1322-1333, 2016
BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci
L Pasqualucci, A Migliazza, N Fracchiolla, C William, A Neri, L Baldini, ...
Proceedings of the National Academy of Sciences 95 (20), 11816-11821, 1998
Transcriptional control of adipose lipid handling by IRF4
J Eguchi, X Wang, S Yu, EE Kershaw, PC Chiu, J Dushay, JL Estall, ...
Cell metabolism 13 (3), 249-259, 2011
Transcriptional analysis of the B cell germinal center reaction
U Klein, Y Tu, GA Stolovitzky, JL Keller, J Haddad Jr, V Miljkovic, ...
Proceedings of the National Academy of Sciences 100 (5), 2639-2644, 2003
Loss of the B-lineage–specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma
I Schwering, A Bräuninger, U Klein, B Jungnickel, M Tinguely, V Diehl, ...
Blood, The Journal of the American Society of Hematology 101 (4), 1505-1512, 2003
Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4
K Ochiai, M Maienschein-Cline, G Simonetti, J Chen, R Rosenthal, ...
Immunity 38 (5), 918-929, 2013
Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease
T Goossens, U Klein, R Küppers
Proceedings of the National Academy of Sciences 95 (5), 2463-2468, 1998
Somatic hypermutation in normal and transformed human B cells
U Klien, T Goasens, M Fischer, H Kanzler, A Braeuninger, K Rajewsky, ...
Immunological reviews 162 (1), 261-280, 1998
Evidence for a large compartment of IgM-expressing memory B cells in humans
U Klein, R Küppers, K Rajewsky
Blood, The Journal of the American Society of Hematology 89 (4), 1288-1298, 1997
Quantitative noise analysis for gene expression microarray experiments
Y Tu, G Stolovitzky, U Klein
Proceedings of the National Academy of Sciences 99 (22), 14031-14036, 2002
Identification of Hodgkin and Reed-Sternberg cell-specific genes by gene expression profiling
R Küppers, U Klein, I Schwering, V Distler, A Bräuninger, G Cattoretti, ...
The Journal of clinical investigation 111 (4), 529-537, 2003
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