Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43 M Polymenidou, C Lagier-Tourenne, KR Hutt, SC Huelga, J Moran, ... Nature neuroscience 14 (4), 459-468, 2011 | 1445 | 2011 |
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs C Lagier-Tourenne, M Polymenidou, KR Hutt, AQ Vu, M Baughn, ... Nature neuroscience 15 (11), 1488-1497, 2012 | 858 | 2012 |
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43 ES Arnold, SC Ling, SC Huelga, C Lagier-Tourenne, M Polymenidou, ... Proceedings of the National Academy of Sciences 110 (8), E736-E745, 2013 | 530 | 2013 |
Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins SC Huelga, AQ Vu, JD Arnold, TY Liang, PP Liu, BY Yan, JP Donohue, ... Cell reports 1 (2), 167-178, 2012 | 519 | 2012 |
LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance ML Wilbert, SC Huelga, K Kapeli, TJ Stark, TY Liang, SX Chen, BY Yan, ... Molecular cell 48 (2), 195-206, 2012 | 318 | 2012 |
Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses K Kapeli, GA Pratt, AQ Vu, KR Hutt, FJ Martinez, B Sundararaman, ... Nature communications 7 (1), 12143, 2016 | 194 | 2016 |
SONAR discovers RNA-binding proteins from analysis of large-scale protein-protein interactomes KW Brannan, W Jin, SC Huelga, CAS Banks, JM Gilmore, L Florens, ... Molecular cell 64 (2), 282-293, 2016 | 178 | 2016 |
Protein-RNA networks regulated by normal and ALS-associated mutant HNRNPA2B1 in the nervous system FJ Martinez, GA Pratt, EL Van Nostrand, R Batra, SC Huelga, K Kapeli, ... Neuron 92 (4), 780-795, 2016 | 177 | 2016 |
Resources for the comprehensive discovery of functional RNA elements B Sundararaman, L Zhan, SM Blue, R Stanton, K Elkins, S Olson, X Wei, ... Molecular cell 61 (6), 903-913, 2016 | 149 | 2016 |
Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl) imidazole at 2.0-Å resolution SC Gay, MB Shah, JC Talakad, K Maekawa, AG Roberts, PR Wilderman, ... Molecular pharmacology 77 (4), 529-538, 2010 | 105 | 2010 |
An efficient method for identifying gene fusions by targeted RNA sequencing from fresh frozen and FFPE samples JA Scolnick, M Dimon, IC Wang, SC Huelga, DA Amorese PLoS One 10 (7), e0128916, 2015 | 53 | 2015 |
RNA-binding protein CPEB1 remodels host and viral RNA landscapes R Batra, TJ Stark, AE Clark, JP Belzile, EC Wheeler, BA Yee, H Huang, ... Nature structural & molecular biology 23 (12), 1101-1110, 2016 | 46 | 2016 |
Methods and compositions for pooling amplification primers S Huelga, J Scolnick, D Amorese US Patent App. 15/047,448, 2016 | 27 | 2016 |
Digital measurements from targeted sequencing J Scolnick, B Schroeder, D Amorese, SC Huelga US Patent 10,102,337, 2018 | 25 | 2018 |
Experimental and computational considerations in the study of RNA-binding protein-RNA interactions EL Van Nostrand, SC Huelga, GW Yeo RNA Processing: Disease and Genome-wide Probing, 1-28, 2016 | 19 | 2016 |
Molecular tag attachment and transfer DA Amorese, SC Huelga, B Li US Patent 10,190,155, 2019 | 1 | 2019 |
Molecular tag attachment and transfer DA Amorese, SC Huelga, B Li US Patent 10,927,405, 2021 | | 2021 |
Digital measurements from targeted sequencing J Scolnick, D Amorese, SC HUELGA, B Schroeder | | 2021 |
A Simple Method for RNA-Seq From Mixed Microbe/Host Samples M Peterson, IC Wang, S Huelga, B Li, KS Schwalm, DL Dinwiddie, ... 한국미생물학회 학술대회논문집, 106-106, 2019 | | 2019 |
Digital measurements from targeted sequencing J Scolnick, BG Schroeder, DA Amorese, SC Huelga US Patent App. 16/124,304, 2019 | | 2019 |