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Decoding and unlocking the BCL-2 dependency of cancer cells P Juin, O Geneste, F Gautier, S Depil, M Campone Nature Reviews Cancer 13 (7), 455-465, 2013 | 292 | 2013 |
Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members T Gallenne, F Gautier, L Oliver, E Hervouet, B Noël, JA Hickman, ... Journal of Cell Biology 185 (2), 279-290, 2009 | 195 | 2009 |
The small organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death F Manero, F Gautier, T Gallenne, N Cauquil, D Grée, PF Cartron, ... Cancer research 66 (5), 2757-2764, 2006 | 168 | 2006 |
Efficient mitochondrial glutamine targeting prevails over glioblastoma metabolic plasticity K Oizel, C Chauvin, L Oliver, C Gratas, F Geraldo, U Jarry, E Scotet, ... Clinical Cancer Research 23 (20), 6292-6304, 2017 | 100 | 2017 |
STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment S Lohard, N Bourgeois, L Maillet, F Gautier, A Fétiveau, H Lasla, ... Nature communications 11 (1), 259, 2020 | 91 | 2020 |
Bcl-xL controls a switch between cell death modes during mitotic arrest N Bah, L Maillet, J Ryan, S Dubreil, F Gautier, A Letai, P Juin, ... Cell death & disease 5 (6), e1291-e1291, 2014 | 84 | 2014 |
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ANT2 expression under hypoxic conditions produces opposite cell‐cycle behavior in 143B and HepG2 cancer cells A Chevrollier, D Loiseau, F Gautier, Y Malthièry, G Stepien Molecular Carcinogenesis: Published in cooperation with the University of …, 2005 | 63 | 2005 |
Identification of an apoptotic cleavage product of BARD1 as an autoantigen: a potential factor in the antitumoral response mediated by apoptotic bodies F Gautier, I Irminger-Finger, M Grégoire, K Meflah, J Harb Cancer research 60 (24), 6895-6900, 2000 | 63 | 2000 |
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First Evidence That Oligopyridines, α-Helix Foldamers, Inhibit Mcl-1 and Sensitize Ovarian Carcinoma Cells to Bcl-xL-Targeting Strategies C Gloaguen, AS Voisin-Chiret, J Sopkova-de Oliveira Santos, J Fogha, ... Journal of medicinal chemistry 58 (4), 1644-1668, 2015 | 56 | 2015 |
c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1 M Campone, B Noël, C Couriaud, M Grau, Y Guillemin, F Gautier, ... Molecular cancer 10, 1-14, 2011 | 56 | 2011 |
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Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL J Le Pen, M Laurent, K Sarosiek, C Vuillier, F Gautier, S Montessuit, ... Cell death & disease 7 (2), e2083-e2083, 2016 | 49 | 2016 |
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Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model K Oizel, C Yang, O Renoult, F Gautier, QN Do, N Joalland, X Gao, B Ko, ... Cancer & metabolism 8, 1-11, 2020 | 28 | 2020 |