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Joshua J. Yim
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A bright future for precision medicine: advances in fluorescent chemical probe design and their clinical application
M Garland, JJ Yim, M Bogyo
Cell chemical biology 23 (1), 122-136, 2016
2512016
Comparative Metabolomics Reveals Biogenesis of Ascarosides, a Modular Library of Small-Molecule Signals in C. elegans
SH Von Reuss, N Bose, J Srinivasan, JJ Yim, JC Judkins, PW Sternberg, ...
Journal of the American Chemical Society 134 (3), 1817-1824, 2012
2282012
PD-1 inhibitory receptor downregulates asparaginyl endopeptidase and maintains Foxp3 transcription factor stability in induced regulatory T cells
C Stathopoulou, A Gangaplara, G Mallett, FA Flomerfelt, LP Liniany, ...
Immunity 49 (2), 247-263. e7, 2018
1242018
Complex small-molecule architectures regulate phenotypic plasticity in a nematode
N Bose, A Ogawa, SH von Reuss, JJ Yim, EJ Ragsdale, RJ Sommer, ...
Angewandte Chemie (International ed. in English) 51 (50), 12438, 2012
1192012
Transcranial magnetic stimulation in ALS: utility of central motor conduction tests
AG Floyd, QP Yu, P Piboolnurak, MX Tang, Y Fang, WA Smith, J Yim, ...
Neurology 72 (6), 498-504, 2009
912009
Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans
AB Artyukhin, JJ Yim, J Srinivasan, Y Izrayelit, N Bose, SH Von Reuss, ...
Journal of Biological Chemistry 288 (26), 18778-18783, 2013
862013
AND-gate contrast agents for enhanced fluorescence-guided surgery
JC Widen, M Tholen, JJ Yim, A Antaris, KM Casey, S Rogalla, A Klaassen, ...
Nature biomedical engineering 5 (3), 264-277, 2021
782021
Sex-specific mating pheromones in the nematode Panagrellus redivivus
A Choe, T Chuman, SH von Reuss, AT Dossey, JJ Yim, R Ajredini, ...
Proceedings of the National Academy of Sciences 109 (51), 20949-20954, 2012
782012
Natural variation in dauer pheromone production and sensing supports intraspecific competition in nematodes
N Bose, JM Meyer, JJ Yim, MG Mayer, GV Markov, A Ogawa, ...
Current Biology 24 (13), 1536-1541, 2014
612014
Optimization of a protease activated probe for optical surgical navigation
JJ Yim, M Tholen, A Klaassen, J Sorger, M Bogyo
Molecular Pharmaceutics 15 (3), 750-758, 2017
542017
Starvation-induced collective behavior in C. elegans
AB Artyukhin, JJ Yim, M Cheong Cheong, L Avery
Scientific reports 5 (1), 10647, 2015
522015
A protease-activated, near-infrared fluorescent probe for early endoscopic detection of premalignant gastrointestinal lesions
JJ Yim, S Harmsen, K Flisikowski, T Flisikowska, H Namkoong, M Garland, ...
Proceedings of the National Academy of Sciences 118 (1), e2008072118, 2021
432021
Linking genomic and metabolomic natural variation uncovers nematode pheromone biosynthesis
JM Falcke, N Bose, AB Artyukhin, C Rödelsperger, GV Markov, JJ Yim, ...
Cell chemical biology 25 (6), 787-796. e12, 2018
392018
B. subtilis GS67 protects C. elegans from Gram-positive pathogens via fengycin-mediated microbial antagonism
I Iatsenko, JJ Yim, FC Schroeder, RJ Sommer
Current Biology 24 (22), 2720-2727, 2014
392014
Synthesis of caeliferins, elicitors of plant immune responses: accessing lipophilic natural products via cross metathesis
I O’Doherty, JJ Yim, EA Schmelz, FC Schroeder
Organic Letters 13 (21), 5900-5903, 2011
342011
Fluorescent image-guided surgery in breast cancer by intravenous application of a quenched fluorescence activity-based probe for cysteine cathepsins in a syngeneic mouse model
FV Suurs, SQ Qiu, JJ Yim, CP Schröder, H Timmer-Bosscha, ES Bensen, ...
EJNMMI research 10, 1-10, 2020
272020
Nematode signaling molecules derived from multimodular assembly of primary metabolic building blocks
JJ Yim, N Bose, JM Meyer, RJ Sommer, FC Schroeder
Organic letters 17 (7), 1648-1651, 2015
212015
Design of Optical‐Imaging Probes by Screening of Diverse Substrate Libraries Directly in Disease‐Tissue Extracts
M Tholen, JJ Yim, K Groborz, E Yoo, BA Martin, NS van den Berg, M Drag, ...
Angewandte Chemie International Edition 59 (43), 19143-19152, 2020
202020
Synthetic and biological approaches to map substrate specificities of proteases
S Chen, JJ Yim, M Bogyo
Biological chemistry 401 (1), 165-182, 2019
192019
A protease-activated fluorescent probe allows rapid visualization of keratinocyte carcinoma during excision
E Walker, Y Liu, IY Kim, M Biro, SR Iyer, H Ezaldein, J Scott, M Merati, ...
Cancer research 80 (10), 2045-2055, 2020
172020
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