Analysis of cardiac myocyte maturation using CASAAV, a platform for rapid dissection of cardiac myocyte gene function in vivo Y Guo, NJ VanDusen, L Zhang, W Gu, I Sethi, S Guatimosim, Q Ma, ... Circulation research 120 (12), 1874-1888, 2017 | 118 | 2017 |
A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers BN Akerberg, F Gu, NJ VanDusen, X Zhang, R Dong, K Li, B Zhang, ... Nature communications 10 (1), 4907, 2019 | 111 | 2019 |
A global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissues I Sethi, RA Romano, C Gluck, K Smalley, B Vojtesek, MJ Buck, S Sinha BMC genomics 16, 1-15, 2015 | 75 | 2015 |
Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor Y Guo, BD Jardin, P Zhou, I Sethi, BN Akerberg, CN Toepfer, Y Ai, Y Li, ... Nature communications 9 (1), 3837, 2018 | 73 | 2018 |
Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling Y Guo, Y Cao, BD Jardin, I Sethi, Q Ma, B Moghadaszadeh, EC Troiano, ... Proceedings of the National Academy of Sciences 118 (2), e2008861118, 2021 | 48 | 2021 |
Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation NJ VanDusen, JY Lee, W Gu, CE Butler, I Sethi, Y Zheng, JS King, P Zhou, ... Nature communications 12 (1), 4442, 2021 | 41 | 2021 |
Role of chromatin and transcriptional co-regulators in mediating p63-genome interactions in keratinocytes I Sethi, S Sinha, MJ Buck BMC genomics 15, 1-17, 2014 | 39 | 2014 |
Evolutionary re-wiring of p63 and the epigenomic regulatory landscape in keratinocytes and its potential implications on species-specific gene expression and phenotypes I Sethi, C Gluck, H Zhou, MJ Buck, S Sinha Nucleic acids research 45 (14), 8208-8224, 2017 | 38 | 2017 |
Reactivation of super-enhancers by KLF4 in human Head and Neck Squamous Cell Carcinoma M Tsompana, C Gluck, I Sethi, I Joshi, J Bard, NJ Nowak, S Sinha, ... Oncogene 39 (2), 262-277, 2020 | 17 | 2020 |
GATA4 regulates developing endocardium through interaction with ETS1 P Zhou, Y Zhang, I Sethi, L Ye, MA Trembley, Y Cao, BN Akerberg, F Xiao, ... Circulation research 131 (11), e152-e168, 2022 | 10 | 2022 |
Molecular profiling establishes genetic features predictive of the efficacy of the p110β inhibitor KIN-193 I Sethi, Z Cai, TM Roberts, GC Yuan Cancer research 79 (17), 4524-4531, 2019 | 7 | 2019 |
Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer X Gao, Y Wang, CF Ribeiro, C Manokaran, H Chang, T Von, S Rodrigues, ... Molecular Cancer Research 20 (5), 673-685, 2022 | 6 | 2022 |
Dynamic changes in P300 enhancers and enhancer-promoter contacts control mouse cardiomyocyte maturation P Zhou, NJ VanDusen, Y Zhang, Y Cao, I Sethi, R Hu, S Zhang, G Wang, ... Developmental Cell 58 (10), 898-914. e7, 2023 | 5 | 2023 |
Spatial mapping of human hematopoiesis at single-cell resolution reveals aging-associated topographic remodeling A Sarachakov, A Varlamova, V Svekolkin, M Polyakova, I Valencia, ... Blood 142 (26), 2282-2295, 2023 | 4 | 2023 |
Sarcomeres regulate cardiomyocyte maturation through MRTF-SRF signaling Y Guo, BD Jardin, I Sethi, Q Ma, B Moghadaszadeh, EC Troiano, ... bioRxiv, 824185, 2019 | 3 | 2019 |
An integrated genomic approach identifies follistatin as a target of the p63-epidermal growth factor receptor oncogenic network in head and neck squamous cell carcinoma A Oyelakin, J Sosa, KB Nayak, A Glathar, C Gluck, I Sethi, M Tsompana, ... NAR cancer 5 (3), zcad038, 2023 | 1 | 2023 |
Transcriptomic-Based Microenvironment Classification Reveals Precision Medicine Strategies for PDAC B George, O Kudryashova, A Kravets, S Thalji, S Malarkannan, ... Gastroenterology, 2024 | | 2024 |
Single Cell Resolution Spatial Mapping of Human Hematopoiesis Reveals Aging-Associated Topographic Remodeling A Sarachakov, A Varlamova, V Svekolkin, I Galkin, I Valencia, ... bioRxiv, 2023.04. 28.538715, 2023 | | 2023 |
Mutual Potentiation Between Myofibril Assembly and Serum Response Factor in Cardiomyocyte Maturation Y Guo, B Jardin, I Sethi, B Moghadaszadeh, A Beggs, W Pu Circulation Research 125 (Suppl_1), A920-A920, 2019 | | 2019 |
RNF20/40 Regulates Cardiomyocyte Maturation NJ Vandusen, JY Lee, W Gu, I Sethi, S Suo, J King, Y Zheng, Y Guo, ... Circulation Research 125 (Suppl_1), A658-A658, 2019 | | 2019 |