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Bobby Thomas
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Parkinson's disease
B Thomas, MF Beal
Human molecular genetics 16 (R2), R183-R194, 2007
11452007
S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function
KKK Chung, B Thomas, X Li, O Pletnikova, JC Troncoso, L Marsh, ...
Science 304 (5675), 1328-1331, 2004
8702004
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
E Andres-Mateos, C Perier, L Zhang, B Blanchard-Fillion, TM Greco, ...
Proceedings of the National Academy of Sciences 104 (37), 14807-14812, 2007
5682007
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis
LI Zhang, M Shimoji, B Thomas, DJ Moore, SW Yu, NI Marupudi, R Torp, ...
Human molecular genetics 14 (14), 2063-2073, 2005
5422005
Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice
F Yin, R Banerjee, B Thomas, P Zhou, L Qian, T Jia, X Ma, Y Ma, ...
Journal of Experimental Medicine 207 (1), 117-128, 2010
5092010
Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2
D Ramonet, JPL Daher, BM Lin, K Stafa, J Kim, R Banerjee, M Westerlund, ...
PloS one 6 (4), e18568, 2011
4582011
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis
N Sen, MR Hara, MD Kornberg, MB Cascio, BI Bae, N Shahani, B Thomas, ...
Nature cell biology 10 (7), 866-873, 2008
4462008
Loss of locus coeruleus neurons and reduced startle in parkin null mice
R Von Coelln, B Thomas, JM Savitt, KL Lim, M Sasaki, EJ Hess, ...
Proceedings of the National Academy of Sciences 101 (29), 10744-10749, 2004
4072004
Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis
R Banerjee, AA Starkov, MF Beal, B Thomas
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1792 (7), 651-663, 2009
2992009
Neuroprotection by pharmacologic blockade of the GAPDH death cascade
MR Hara, B Thomas, MB Cascio, BI Bae, LD Hester, VL Dawson, ...
Proceedings of the National Academy of Sciences 103 (10), 3887-3889, 2006
2792006
Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function
C Wang, HS Ko, B Thomas, F Tsang, KCM Chew, SP Tay, MWL Ho, ...
Human molecular genetics 14 (24), 3885-3897, 2005
2432005
Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications
R Banerjee, MF Beal, B Thomas
Trends in neurosciences 33 (12), 541-549, 2010
2342010
Distinct Nrf2 signaling mechanisms of fumaric acid esters and their role in neuroprotection against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced experimental …
M Ahuja, NA Kaidery, L Yang, N Calingasan, N Smirnova, A Gaisin, ...
Journal of Neuroscience 36 (23), 6332-6351, 2016
1912016
Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia
F Yin, M Dumont, R Banerjee, Y Ma, H Li, MT Lin, MF Beal, C Nathan, ...
The FASEB Journal 24 (12), 4639, 2010
1912010
Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine)
E Andres-Mateos, R Mejias, M Sasaki, X Li, BM Lin, S Biskup, L Zhang, ...
Journal of Neuroscience 29 (50), 15846-15850, 2009
1792009
Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription
L Yang, NY Calingasan, B Thomas, RK Chaturvedi, M Kiaei, EJ Wille, ...
PloS one 4 (6), e5757, 2009
1782009
Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease
NA Kaidery, R Banerjee, L Yang, NA Smirnova, DM Hushpulian, KT Liby, ...
Antioxidants & redox signaling 18 (2), 139-157, 2013
1662013
Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity
C Stack, S Jainuddin, C Elipenahli, M Gerges, N Starkova, AA Starkov, ...
Human molecular genetics 23 (14), 3716-3732, 2014
1482014
Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced neurotoxicity
KP Mohanakumar, D Muralikrishnan, B Thomas
Brain research 864 (2), 281-290, 2000
1462000
Melatonin protects against oxidative stress caused by 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine in the mouse nigrostriatum
B Thomas, KP Mohanakumar
Journal of pineal research 36 (1), 25-32, 2004
1452004
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