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Ashot S. Harutyunyan
Ashot S. Harutyunyan
Department of Human Genetics, McGill University
Verified email at mail.mcgill.ca
Title
Cited by
Cited by
Year
Somatic mutations of calreticulin in myeloproliferative neoplasms
T Klampfl, H Gisslinger, AS Harutyunyan, H Nivarthi, E Rumi, JD Milosevic, ...
New England Journal of Medicine 369 (25), 2379-2390, 2013
23492013
A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease
A Zimprich, A Benet-Pagès, W Struhal, E Graf, SH Eck, MN Offman, ...
The American Journal of Human Genetics 89 (1), 168-175, 2011
10542011
JAK2 or CALR mutation status defines subtypes of essential thrombocythemia with substantially different clinical course and outcomes
E Rumi, D Pietra, V Ferretti, T Klampfl, AS Harutyunyan, JD Milosevic, ...
Blood 123 (10), 1544-1551, 2014
7452014
A common JAK2 haplotype confers susceptibility to myeloproliferative neoplasms
D Olcaydu, A Harutyunyan, R Jäger, T Berg, B Gisslinger, I Pabinger, ...
Nature genetics 41 (4), 450-454, 2009
4312009
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape
DN Weinberg, S Papillon-Cavanagh, H Chen, Y Yue, X Chen, ...
Nature 573 (7773), 281-286, 2019
3932019
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis
AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ...
Nature communications 10 (1), 1262, 2019
2602019
p53 lesions in leukemic transformation
A Harutyunyan, T Klampfl, M Cazzola, R Kralovics
New England Journal of Medicine 364 (5), 488-490, 2011
2512011
H3. 3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas
M Pathania, N De Jay, N Maestro, AS Harutyunyan, J Nitarska, ...
Cancer cell 32 (5), 684-700. e9, 2017
2292017
Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression
T Klampfl, A Harutyunyan, T Berg, B Gisslinger, M Schalling, K Bagienski, ...
Blood 118 (1), 167-176, 2011
2072011
Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms
W Tapper, AV Jones, R Kralovics, AS Harutyunyan, K Zoi, W Leung, ...
Nature Communications 6, 2015
1842015
Deletions of the transcription factor Ikaros in myeloproliferative neoplasms
R Jäger, H Gisslinger, F Passamonti, E Rumi, T Berg, B Gisslinger, ...
Leukemia 24 (7), 1290-1298, 2010
1802010
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas
B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ...
Cancer cell 35 (5), 782-797. e8, 2019
1752019
Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies
A Puda, JD Milosevic, T Berg, T Klampfl, AS Harutyunyan, B Gisslinger, ...
American journal of hematology 87 (3), 245-250, 2012
1262012
Histone H3. 3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ...
Cell 183 (6), 1617-1633. e22, 2020
1112020
CALR exon 9 mutations are somatically acquired events in familial cases of essential thrombocythemia or primary myelofibrosis
E Rumi, AS Harutyunyan, D Pietra, JD Milosevic, IC Casetti, M Bellini, ...
Blood 123 (15), 2416-2419, 2014
1032014
Clinical significance of genetic aberrations in secondary acute myeloid leukemia
JD Milosevic, A Puda, L Malcovati, T Berg, M Hofbauer, A Stukalov, ...
American journal of hematology 87 (11), 1010-1016, 2012
1002012
Population genetics of familial Mediterranean fever: a review
L Yepiskoposyan, A Harutyunyan
European Journal of Human Genetics 15 (9), 911-916, 2007
972007
H3 K27M and EZHIP impede H3K27-methylation spreading by inhibiting allosterically stimulated PRC2
SU Jain, AQ Rashoff, SD Krabbenhoft, D Hoelper, TJ Do, TJ Gibson, ...
Molecular cell 80 (4), 726-735. e7, 2020
942020
Germ-line JAK2 mutations in the kinase domain are responsible for hereditary thrombocytosis and are resistant to JAK2 and HSP90 inhibitors
C Marty, C Saint-Martin, C Pecquet, S Grosjean, J Saliba, C Mouton, ...
Blood 123 (9), 1372-1383, 2014
912014
The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms
D Olcaydu, E Rumi, A Harutyunyan, F Passamonti, D Pietra, C Pascutto, ...
Haematologica 96 (3), 367-374, 2011
832011
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