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Céline Galvagnion
Céline Galvagnion
Associate Professor, Department of Drug Design and Pharmacology, University of Copenhagen
Verified email at sund.ku.dk - Homepage
Title
Cited by
Cited by
Year
Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation
AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, ...
Proceedings of the National Academy of Sciences 111 (21), 7671-7676, 2014
6732014
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, ...
Nature chemical biology 11 (3), 229-234, 2015
6262015
Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation
P Flagmeier, G Meisl, M Vendruscolo, TPJ Knowles, CM Dobson, ...
Proceedings of the National Academy of Sciences 113 (37), 10328-10333, 2016
3042016
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, ...
Proceedings of the National Academy of Sciences 114 (6), E1009-E1017, 2017
3002017
Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
C Galvagnion, JWP Brown, MM Ouberai, P Flagmeier, M Vendruscolo, ...
Proceedings of the National Academy of Sciences 113 (26), 7065-7070, 2016
2922016
The role of lipids interacting with α-synuclein in the pathogenesis of Parkinson’s disease
C Galvagnion
Journal of Parkinson's disease 7 (3), 433-450, 2017
2352017
α-Synuclein senses lipid packing defects and induces lateral expansion of lipids leading to membrane remodeling
MM Ouberai, J Wang, MJ Swann, C Galvagnion, T Guilliams, CM Dobson, ...
Journal of Biological Chemistry 288 (29), 20883-20895, 2013
2222013
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ...
Nature chemistry 10 (6), 673-683, 2018
2182018
Ostwald’s rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers
A Levin, TO Mason, L Adler-Abramovich, AK Buell, G Meisl, C Galvagnion, ...
Nature communications 5 (1), 5219, 2014
2082014
Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy
D Pinotsi, AK Buell, C Galvagnion, CM Dobson, GS Kaminski Schierle, ...
Nano letters 14 (1), 339-345, 2014
1992014
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson’s disease
G Toth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, ...
PloS one 9 (2), e87133, 2014
1602014
The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments
D Granata, F Baftizadeh, J Habchi, C Galvagnion, A De Simone, ...
Scientific reports 5 (1), 15449, 2015
1402015
Conformational stability and folding mechanisms of dimeric proteins
JAO Rumfeldt, C Galvagnion, KA Vassall, EM Meiering
Progress in biophysics and molecular biology 98 (1), 61-84, 2008
1242008
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine
M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, ...
ACS chemical biology 13 (8), 2308-2319, 2018
1042018
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces
JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, ...
Scientific reports 6 (1), 36010, 2016
912016
C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH
IM van der Wateren, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion
Chemical science 9 (25), 5506-5516, 2018
772018
An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils
ED Agerschou, P Flagmeier, T Saridaki, C Galvagnion, D Komnig, L Heid, ...
Elife 8, e46112, 2019
622019
Lipid dynamics and phase transition within α-synuclein amyloid fibrils
C Galvagnion, D Topgaard, K Makasewicz, AK Buell, S Linse, E Sparr, ...
The journal of physical chemistry letters 10 (24), 7872-7877, 2019
432019
Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell
A Chattopadhyay, CJ O’Connor, F Zhang, C Galvagnion, WRJD Galloway, ...
Scientific reports 6 (1), 23732, 2016
412016
Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation
C Galvagnion, FR Marlet, S Cerri, AHV Schapira, F Blandini, DA Di Monte
Brain 145 (3), 1038-1051, 2022
392022
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