Paul Clapham
Paul Clapham
Professor of Molecular Medicine, University of Massachusetts Medical School
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The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus
AG Dalgleish, PCL Beverley, PR Clapham, DH Crawford, MF Greaves, ...
Nature 312 (5996), 763-767, 1984
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
PJ Maddon, AG Dalgleish, JS McDougal, PR Clapham, RA Weiss, R Axel
Cell 47 (3), 333-348, 1986
Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist
G Simmons, PR Clapham, L Picard, RE Offord, MM Rosenkilde, ...
Science 276 (5310), 276-279, 1997
CD4-independent infection by HIV-2 is mediated by fusin/CXCR4
MJ Endres, PR Clapham, M Marsh, M Ahuja, JD Turner, A McKnight, ...
Cell 87 (4), 745-756, 1996
Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients
RA Weiss, PR Clapham, R Cheingsong-Popov, AG Dalgleish, CA Carne, ...
Nature 316 (6023), 69-72, 1985
A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus
TN Kledal, MM Rosenkilde, F Coulin, G Simmons, AH Johnsen, S Alouani, ...
Science 277 (5332), 1656-1659, 1997
Identification of the residues in human CD4 critical for the binding of HIV
J Arthos, KC Deen, MA Chaikin, JA Fornwald, G Sathe, QJ Sattentau, ...
Cell 57 (3), 469-481, 1989
Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity
M Mack, B Luckow, PJ Nelson, J Cihak, G Simmons, PR Clapham, ...
The Journal of experimental medicine 187 (8), 1215-1224, 1998
Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells
PR Clapham, JN Weber, D Whitby, K McIntosh, AG Dalgleish, PJ Maddon, ...
Nature 337 (6205), 368-370, 1989
Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry
G Simmons, D Wilkinson, JD Reeves, MT Dittmar, S Beddows, J Weber, ...
Journal of virology 70 (12), 8355-8360, 1996
Variable and conserved neutralization antigens of human immunodeficiency virus
RA Weiss, PR Clapham, JN Weber, AG Dalgleish, LA Lasky, PW Berman
Nature 324 (6097), 572-575, 1986
Cell surface receptors, virus entry and tropism of primate lentiviruses
PR Clapham, McKnight
Journal of General Virology 83 (8), 1809-1829, 2002
Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by simian immunodeficiency virus
PR Clapham, D Blanc, RA Weiss
Virology 181 (2), 703-715, 1991
Human immunodeficiency virus infection in two cohorts of homosexual men: neutralising sera and association of anti-gag antibody with prognosis
JN Weber, RA Weiss, C Roberts, I Weller, RS Tedder, PR Clapham, ...
The Lancet 329 (8525), 119-122, 1987
The V3 Loops of the HIV-1 and HTV-2 Surface Glycoproteins Contain Proteolytic Cleavage Sites: A Possible Function in Viral Fusion?
AIDS research and human retroviruses 7 (1), 3-16, 1991
HIV-1 receptors and cell tropism
PR Clapham, A McKnight
British medical bulletin 58 (1), 43-59, 2001
HIV infection does not require endocytosis of its receptor, CD4
PJ Maddon, JS McDougal, PR Clapham, AG Dalgleish, S Jamal, ...
Cell 54 (6), 865-874, 1988
The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity
AEI Proudfoot, S Fritchley, F Borlat, JP Shaw, F Vilbois, C Zwahlen, ...
Journal of Biological Chemistry 276 (14), 10620-10626, 2001
KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells
JT Stine, C Wood, M Hill, A Epp, CJ Raport, VL Schweickart, Y Endo, ...
Blood, The Journal of the American Society of Hematology 95 (4), 1151-1157, 2000
Human T‐cell leukemia virus type I: induction of syncytia and inhibition by patients' sera
K Nagy, P Clapham, R Cheingsong‐Popov, RA Weiss
International Journal of Cancer 32 (3), 321-328, 1983
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