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Michael Kurnellas
Michael Kurnellas
Verificeret mail på stanford.edu
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Plasma membrane calcium ATPase deficiency causes neuronal pathology in the spinal cord: a potential mechanism for neurodegeneration in multiple sclerosis and spinal cord injury
MP Kurnellas, A Nicot, GE Shull, S Elkabes
The FASEB journal: official publication of the Federation of American …, 2005
1112005
Optimized proteomic analysis of a mouse model of cerebellar dysfunction using amine‐specific isobaric tags
J Hu, J Qian, O Borisov, S Pan, Y Li, T Liu, L Deng, K Wannemacher, ...
Proteomics 6 (15), 4321-4334, 2006
912006
Therapeutic effects of systemic administration of chaperone αB-crystallin associated with binding proinflammatory plasma proteins
JB Rothbard, MP Kurnellas, S Brownell, CM Adams, L Su, RC Axtell, ...
Journal of Biological Chemistry 287 (13), 9708-9721, 2012
892012
Identification of differentially expressed proteins in experimental autoimmune encephalomyelitis (EAE) by proteomic analysis of the spinal cord
T Liu, KC Donahue, J Hu, MP Kurnellas, JE Grant, H Li, S Elkabes
Journal of proteome research 6 (7), 2565-2575, 2007
732007
Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation
MP Kurnellas, CM Adams, RA Sobel, L Steinman, JB Rothbard
Science translational medicine 5 (179), 179ra42-179ra42, 2013
702013
Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis
MP Kurnellas, SE Brownell, L Su, AV Malkovskiy, J Rajadas, G Dolganov, ...
Journal of Biological Chemistry 287 (43), 36423-36434, 2012
572012
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons
MP Kurnellas, AK Lee, H Li, L Deng, DJ Ehrlich, S Elkabes
Molecular and Cellular Neuroscience 34 (2), 178-188, 2007
562007
Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons
MP Kurnellas, H Li, MR Jain, SN Giraud, AB Nicot, A Ratnayake, ...
Cell Death & Differentiation 17 (9), 1501-1510, 2010
542010
Mechanisms of neuronal damage in multiple sclerosis and its animal models: role of calcium pumps and exchangers
MP Kurnellas, KC Donahue, S Elkabes
Biochemical Society Transactions 35 (5), 923-926, 2007
542007
Chaperone activity of α B-crystallin is responsible for its incorrect assignment as an autoantigen in multiple sclerosis
JB Rothbard, X Zhao, O Sharpe, MJ Strohman, M Kurnellas, ED Mellins, ...
The Journal of Immunology 186 (7), 4263-4268, 2011
422011
Temporal pattern of plasma membrane calcium ATPase 2 expression in the spinal cord correlates with the course of clinical symptoms in two rodent models of autoimmune …
A Nicot, M Kurnellas, S Elkabes
European Journal of Neuroscience 21 (10), 2660-2670, 2005
392005
Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease
MP Kurnellas, EEB Ghosn, JM Schartner, J Baker, JJ Rothbard, ...
Proceedings of the National Academy of Sciences 112 (49), 15016-15023, 2015
262015
Calcium responses of chicken trigeminal ganglion neurons to methyl anthranilate and capsaicin
ML Kirifides, MP Kurnellas, L Clark, BP Bryant
Journal of experimental biology 207 (5), 715-722, 2004
222004
Reductions in motor unit number estimates (MUNE) precede motor neuron loss in the plasma membrane calcium ATPase 2 (PMCA2)-heterozygous mice
N Souayah, A Sharovetskaya, MP Kurnellas, M Myerson, JS Deitch, ...
Experimental neurology 214 (2), 341-346, 2008
212008
Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease
MP Kurnellas, JM Schartner, CG Fathman, A Jagger, L Steinman, ...
Journal of Experimental Medicine 211 (9), 1847-1856, 2014
172014
Janus faces of amyloid proteins in neuroinflammation
L Steinman, JB Rothbard, MP Kurnellas
Journal of clinical immunology 34, 61-63, 2014
142014
Role of plasma membrane calcium ATPase isoform 2 in neuronal function in the cerebellum and spinal cord
MP Kurnellas, AK Lee, K Szczepanowski, S Elkabes
Annals of the New York Academy of Sciences 1099 (1), 287-291, 2007
122007
Piet Mondrian’s trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011
L Steinman, RC Axtell, D Barbieri, R Bhat, SE Brownell, BA De Jong, ...
Multiple Sclerosis Journal 19 (1), 5-14, 2013
102013
Small heat shock proteins, amyloid fibrils, and nicotine stimulate a common immune suppressive pathway with implications for future therapies
JB Rothbard, MP Kurnellas, SS Ousman, S Brownell, JJ Rothbard, ...
Cold Spring Harbor Perspectives in Medicine 9 (7), a034223, 2019
92019
Self-assembling peptides form immune suppressive amyloid fibrils effective in autoimmune encephalomyelitis
MP Kurnellas, JB Rothbard, L Steinman
Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and …, 2015
92015
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Artikler 1–20