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Aurore Lyon
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Computational techniques for ECG analysis and interpretation in light of their contribution to medical advances
A Lyon, A Mincholé, JP Martínez, P Laguna, B Rodriguez
Journal of The Royal Society Interface 15 (138), 20170821, 2018
2222018
Machine learning in the electrocardiogram
A Mincholé, J Camps, A Lyon, B Rodríguez
Journal of electrocardiology 57, S61-S64, 2019
1282019
Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies
H Sutanto, A Lyon, J Lumens, U Schotten, D Dobrev, J Heijman
Progress in biophysics and molecular biology 157, 54-75, 2020
902020
Distinct ECG phenotypes identified in hypertrophic cardiomyopathy using machine learning associate with arrhythmic risk markers
A Lyon, R Ariga, A Mincholé, M Mahmod, E Ormondroyd, P Laguna, ...
Frontiers in physiology 9, 328675, 2018
852018
Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop
B Rodriguez, A Carusi, N Abi-Gerges, R Ariga, O Britton, G Bub, ...
Ep Europace 18 (9), 1287-1298, 2015
532015
Electrocardiogram phenotypes in hypertrophic cardiomyopathy caused by distinct mechanisms: apico-basal repolarization gradients vs. Purkinje-myocardial coupling abnormalities
A Lyon, A Bueno-Orovio, E Zacur, R Ariga, V Grau, S Neubauer, ...
EP Europace 20 (suppl_3), iii102-iii112, 2018
392018
Improving long QT syndrome diagnosis by a polynomial-based T-wave morphology characterization
BJM Hermans, FC Bennis, AS Vink, T Koopsen, A Lyon, AAM Wilde, ...
Heart Rhythm 17 (5), 752-758, 2020
272020
The prognostic impact of mechanical atrial dysfunction and atrial fibrillation in heart failure with preserved ejection fraction
J Weerts, A Barandiarán Aizpurua, MTHM Henkens, A Lyon, ...
European Heart Journal-Cardiovascular Imaging 23 (1), 74-84, 2022
192022
Parameter subset reduction for patient-specific modelling of arrhythmogenic cardiomyopathy-related mutation carriers in the CircAdapt model
N van Osta, A Lyon, F Kirkels, T Koopsen, T van Loon, MJ Cramer, ...
Philosophical Transactions of the Royal Society A 378 (2173), 20190347, 2020
152020
Both beat-to-beat changes in RR-interval and left ventricular filling time determine ventricular function during atrial fibrillation
A Lyon, M van Mourik, L Cruts, J Heijman, SCAM Bekkers, U Schotten, ...
EP Europace 23 (Supplement_1), i21-i28, 2021
142021
Differentiating the effects of β-adrenergic stimulation and stretch on calcium and force dynamics using a novel electromechanical cardiomyocyte model
A Lyon, LJ Dupuis, T Arts, HJGM Crijns, FW Prinzen, T Delhaas, ...
American Journal of Physiology-Heart and Circulatory Physiology 319 (3 …, 2020
142020
Electromechanical substrate characterization in arrhythmogenic cardiomyopathy using imaging-based patient-specific computer simulations
N van Osta, F Kirkels, A Lyon, T Koopsen, T van Loon, MJ Cramer, ...
EP Europace 23 (Supplement_1), i153-i160, 2021
132021
Uncertainty quantification of regional cardiac tissue properties in arrhythmogenic cardiomyopathy using adaptive multiple importance sampling
N Van Osta, FP Kirkels, A Lyon, R Meiburg, MJ Cramer, T Delhaas, ...
Frontiers in physiology 12, 738926, 2021
92021
Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation: Analysis of AF-RISK
MJW Van Mourik, VA Arita, A Lyon, J Lumens, R Ruben, JP van Melle, ...
International Journal of Cardiology 360, 29-35, 2022
82022
Improving the clinical understanding of hypertrophic cardiomyopathy by combining patient data, machine learning and computer simulations: a case study
A Lyon, A Mincholé, A Bueno-Orovio, B Rodriguez
Morphologie 103 (343), 169-179, 2019
82019
In silico identification of disrupted myocardial calcium homeostasis as proarrhythmic trigger in arrhythmogenic cardiomyopathy
A Lyon, CJM Van Opbergen, M Delmar, J Heijman, TAB Van Veen
Frontiers in physiology 12, 732573, 2021
62021
Computational modeling of cardiac electrophysiology and arrhythmogenesis
NA Trayanova, A Lyon, J Shade, J Heijman
Physiological Reviews, 2023
32023
Extraction of morphological QRS-based biomarkers in hypertrophic cardiomyopathy for risk stratification using L1 regularized logistic regression
A Lyon, A Mincholé, R Ariga, P Laguna, S Neubauer, H Watkins, ...
2015 Computing in Cardiology Conference (CinC), 9-12, 2015
32015
Increased Chamber Resting Tone Is a Key Determinant of Left Ventricular Diastolic Dysfunction
M Tamargo, P Martínez-Legazpi, MÁ Espinosa, A Lyon, I Méndez, ...
Circulation: Heart Failure 16 (12), e010673, 2023
12023
Electrophysiological effects of stretch‐activated ion channels: a systematic computational characterization
M Buonocunto, A Lyon, T Delhaas, J Heijman, J Lumens
The Journal of Physiology, 2023
12023
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Articles 1–20