| Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 F Urano, XZ Wang, A Bertolotti, Y Zhang, P Chung, HP Harding, D Ron science 287 (5453), 664-666, 2000 | 3414 | 2000 |
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA M Calfon, H Zeng, F Urano, JH Till, SR Hubbard, HP Harding, SG Clark, ... Nature 415 (6867), 92-96, 2002 | 3246 | 2002 |
| Autophagy is activated for cell survival after endoplasmic ReticulumStress M Ogata, S Hino, A Saito, K Morikawa, S Kondo, S Kanemoto, T Murakami, ... Molecular and cellular biology 26 (24), 9220-9231, 2006 | 2107 | 2006 |
| Transcriptional and translational control in the Mammalian unfolded protein response HP Harding, M Calfon, F Urano, I Novoa, D Ron Annual review of cell and developmental biology 18 (1), 575-599, 2002 | 1105 | 2002 |
| Measuring ER stress and the unfolded protein response using mammalian tissue culture system CM Oslowski, F Urano Methods in enzymology 490, 71-92, 2011 | 1045 | 2011 |
| Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome CM Oslowski, T Hara, B O'Sullivan-Murphy, K Kanekura, S Lu, M Hara, ... Cell metabolism 16 (2), 265-273, 2012 | 678 | 2012 |
| Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones T Yoneda, C Benedetti, F Urano, SG Clark, HP Harding, D Ron Journal of cell science 117 (18), 4055-4066, 2004 | 656 | 2004 |
| Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1 KL Lipson, SG Fonseca, S Ishigaki, LX Nguyen, E Foss, R Bortell, ... Cell metabolism 4 (3), 245-254, 2006 | 572 | 2006 |
| Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation H Kadowaki, H Nishitoh, F Urano, C Sadamitsu, A Matsuzawa, K Takeda, ... Cell Death & Differentiation 12 (1), 19-24, 2005 | 485 | 2005 |
| Endoplasmic reticulum stress and pancreatic β-cell death SG Fonseca, J Gromada, F Urano Trends in Endocrinology & Metabolism 22 (7), 266-274, 2011 | 478 | 2011 |
| Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells SG Fonseca, S Ishigaki, CM Oslowski, S Lu, KL Lipson, R Ghosh, ... The Journal of clinical investigation 120 (3), 744-755, 2010 | 431 | 2010 |
| WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic β-cells SG Fonseca, M Fukuma, KL Lipson, LX Nguyen, JR Allen, Y Oka, F Urano Journal of biological chemistry 280 (47), 39609-39615, 2005 | 398 | 2005 |
| IRE1 and efferent signaling from the endoplasmic reticulum F Urano, A Bertolotti, D Ron Journal of cell science 113 (21), 3697-3702, 2000 | 341 | 2000 |
| Transcriptional regulation of VEGF-A by the unfolded protein response pathway R Ghosh, KL Lipson, KE Sargent, AM Mercurio, JS Hunt, D Ron, F Urano PloS one 5 (3), e9575, 2010 | 291 | 2010 |
| Male sterility and enhanced radiation sensitivity in TLS−/− mice M Kuroda, J Sok, L Webb, H Baechtold, F Urano, Y Yin, P Chung, ... The EMBO journal, 2000 | 280 | 2000 |
| A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response F Urano, M Calfon, T Yoneda, C Yun, M Kiraly, SG Clark, D Ron The Journal of cell biology 158 (4), 639-646, 2002 | 258 | 2002 |
| Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions S Ishigaki, A Masuda, Y Fujioka, Y Iguchi, M Katsuno, A Shibata, F Urano, ... Scientific reports 2 (1), 529, 2012 | 255 | 2012 |
| Wolfram syndrome: diagnosis, management, and treatment F Urano Current diabetes reports 16, 1-8, 2016 | 247 | 2016 |
| The role of IRE1α in the degradation of insulin mRNA in pancreatic β-cells KL Lipson, R Ghosh, F Urano PloS one 3 (2), e1648, 2008 | 240 | 2008 |
| Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation K Kubota, DH Lee, M Tsuchiya, CS Young, ET Everett, EA Martinez-Mier, ... Journal of Biological Chemistry 280 (24), 23194-23202, 2005 | 225 | 2005 |
Jana mahadevanWashington University School of MedicineVerified email at dom.wustl.edu
