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A. Jonathan Singh
A. Jonathan Singh
Ferrier Research Institute, Victoria University of Wellington
Verified email at vuw.ac.nz - Homepage
Title
Cited by
Cited by
Year
Microtubule-Stabilizing Activity of Zampanolide, a Potent Macrolide Isolated from the Tongan Marine Sponge Cacospongia mycofijiensis
JJ Field, AJ Singh, A Kanakkanthara, T Halafihi, PT Northcote, JH Miller
Journal of medicinal chemistry 52 (22), 7328-7332, 2009
1202009
Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α, β-heterodimers and microtubules
JJ Field, B Pera, E Calvo, A Canales, D Zurwerra, C Trigili, ...
Chemistry & biology 19 (6), 686-698, 2012
1032012
Microtubule-stabilizing drugs from marine sponges: focus on peloruside A and zampanolide
JH Miller, AJ Singh, PT Northcote
Marine drugs 8 (4), 1059-1079, 2010
852010
Peloruside B, a potent antitumor macrolide from the New Zealand marine sponge Mycale hentscheli: isolation, structure, total synthesis, and bioactivity
AJ Singh, CX Xu, X Xu, LM West, A Wilmes, A Chan, E Hamel, JH Miller, ...
The Journal of organic chemistry 75 (1), 2-10, 2009
652009
Marine Invertebrate Natural Products that Target Microtubules.
JH Miller, JJ Field, A Kanakkanthara, JG Owen, AJ Singh, PT Northcote
Journal of Natural Products 81, 691-702, 2018
542018
Structurally diverse hamigerans from the New Zealand marine sponge Hamigera tarangaensis: NMR-directed isolation, structure elucidation and antifungal activity
AJ Singh, JD Dattelbaum, JJ Field, Z Smart, EF Woolly, JM Barber, ...
Organic & biomolecular chemistry 11 (46), 8041-8051, 2013
392013
The Nitrogenous Hamigerans: Unusual Amino Acid-Derivatized Aromatic Diterpenoid Metabolites from the New Zealand Marine Sponge Hamigera tarangaensis
JD Dattelbaum, AJ Singh, JJ Field, JH Miller, PT Northcote
The Journal of Organic Chemistry 80 (1), 304-312, 2014
352014
Structure–activity studies of the pelorusides: new congeners and semi-synthetic analogues
AJ Singh, M Razzak, P Teesdale-Spittle, TN Gaitanos, A Wilmes, ...
Organic & biomolecular chemistry 9 (12), 4456-4466, 2011
292011
Zampanolides B–E from the Marine Sponge Cacospongia mycofijiensis: Potent Cytotoxic Macrolides with Microtubule-Stabilizing Activity
T Taufa, AJ Singh, CR Harland, V Patel, B Jones, T Halafihi, JH Miller, ...
Journal of natural products 81 (11), 2539-2544, 2018
242018
Inhibition of human vascular endothelial cell migration and capillary-like tube formation by the microtubule-stabilizing agent peloruside A
A Chan, AJ Singh, PT Northcote, JH Miller
Investigational new drugs 33 (3), 564-574, 2015
242015
Hamigerans R and S: Nitrogenous Diterpenoids from the New Zealand Marine Sponge Hamigera tarangaensis
EF Woolly, AJ Singh, ER Russell, JH Miller, PT Northcote
Journal of Natural Products 81 (2), 387-393, 2018
192018
Mitochondrial genome-knockout cells demonstrate a dual mechanism of action for the electron transport complex I inhibitor mycothiazole
KJ Meyer, AJ Singh, A Cameron, AS Tan, DC Leahy, D O’Sullivan, ...
Marine drugs 10 (4), 900-917, 2012
172012
Structure of Echivulgarine, a Pyrrolizidine Alkaloid Isolated from the Pollen of Echium vulgare
E Cairns, MA Hashmi, AJ Singh, G Eakins, M Lein, R Keyzers
Journal of agricultural and food chemistry 63 (33), 7421-7427, 2015
162015
Harnessing Natural Product Diversity for Fluorophore Discovery: Naturally Occurring Fluorescent Hydroxyanthraquinones from the Marine Crinoid Pterometra venusta
AJ Singh, AP Gorka, HR Bokesch, A Wamiru, BR O’Keefe, ...
Journal of Natural Products, 2018
152018
The protein synthesis inhibitors mycalamides A and E have limited susceptibility toward the drug efflux network
V Venturi, C Davies, AJ Singh, JH Matthews, DS Bellows, PT Northcote, ...
Journal of biochemical and molecular toxicology 26 (3), 94-100, 2012
132012
Peloruside A, a microtubule-stabilizing agent, induces aneuploidy in ovarian cancer cells
A Chan, AJ Singh, PT Northcote, JH Miller
Investigational new drugs 34 (4), 424-438, 2016
72016
Peloruside E (22-Norpeloruside A), a Pelorusane Macrolide from the New Zealand Marine Sponge Mycale hentscheli, Retains Microtubule-Stabilizing Properties
SW Hong, AJ Singh, V Patel, ER Russell, JJ Field, JH Miller, PT Northcote
Journal of Natural Products 81 (9), 2125-2128, 2018
62018
Biosynthesis of Nodulisporic Acids: A Multifunctional Monooxygenase Delivers a Complex and Highly Branched Array
AT Richardson, RC Cameron, LJ Stevenson, AJ Singh, Y Lukito, D Berry, ...
Angewandte Chemie International Edition 61 (49), e202213364, 2022
52022
Generation of Alternate Indole Diterpene Architectures in Two Species of Aspergilli
R Bundela, RC Cameron, AJ Singh, RM McLellan, AT Richardson, ...
Journal of the American Chemical Society 145 (5), 2754-2758, 2023
42023
From Marine Organism to Potential Drug: Using Innovative Techniques to Identify and Characterize Novel Compounds− a Bottom-Up Approach
AJ Singh, JJ Field, PH Atkinson, PT Northcote, JH Miller
Bioactive Natural Products: Chemistry and Biology, 2015
42015
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Articles 1–20