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Rachel Rosenthal
Rachel Rosenthal
Verified email at ucl.ac.uk
Title
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Cited by
Year
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ...
Science 351 (6280), 1463-1469, 2016
29912016
Tracking the evolution of non–small-cell lung cancer
M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...
New England Journal of Medicine 376 (22), 2109-2121, 2017
21892017
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446-451, 2017
16932017
Allele-specific HLA loss and immune escape in lung cancer evolution
N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ...
Cell 171 (6), 1259-1271. e11, 2017
11662017
DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution
R Rosenthal, N McGranahan, J Herrero, BS Taylor, C Swanton
Genome biology 17 (1), 1-11, 2016
10432016
Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis
S Turajlic, K Litchfield, H Xu, R Rosenthal, N McGranahan, JL Reading, ...
The Lancet Oncology 18 (8), 1009-1021, 2017
8602017
Neoantigen-directed immune escape in lung cancer evolution
R Rosenthal, EL Cadieux, R Salgado, MA Bakir, DA Moore, CT Hiley, ...
Nature 567 (7749), 479-485, 2019
7312019
Meta-analysis of tumor-and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition
K Litchfield, JL Reading, C Puttick, K Thakkar, C Abbosh, R Bentham, ...
Cell 184 (3), 596-614. e14, 2021
5712021
Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal
S Turajlic, H Xu, K Litchfield, A Rowan, S Horswell, T Chambers, ...
Cell 173 (3), 595-610. e11, 2018
5502018
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies
FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ...
Cancer cell 33 (4), 649-663. e4, 2018
5412018
Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors
FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ...
Immunity 46 (4), 577-586, 2017
4152017
Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes
AK Bentzen, AM Marquard, R Lyngaa, SK Saini, S Ramskov, M Donia, ...
Nature biotechnology 34 (10), 1037-1045, 2016
3332016
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma
K AbdulJabbar, SEA Raza, R Rosenthal, M Jamal-Hanjani, S Veeriah, ...
Nature Medicine 26 (7), 1054-1062, 2020
2302020
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer
K Joshi, MR de Massy, M Ismail, JL Reading, I Uddin, A Woolston, ...
Nature medicine 25 (10), 1549-1559, 2019
1672019
Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution
S Venkatesan, R Rosenthal, N Kanu, N McGranahan, J Bartek, ...
Annals of Oncology 29 (3), 563-572, 2018
1542018
Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma
E Ghorani, R Rosenthal, N McGranahan, JL Reading, M Lynch, KS Peggs, ...
Annals of Oncology 29 (1), 271-279, 2017
1242017
A clonal expression biomarker associates with lung cancer mortality
D Biswas, NJ Birkbak, R Rosenthal, CT Hiley, EL Lim, K Papp, S Boeing, ...
Nature Medicine, 1-9, 2019
892019
The T cell differentiation landscape is shaped by tumour mutations in lung cancer
E Ghorani, JL Reading, JY Henry, MR Massy, R Rosenthal, V Turati, ...
Nature cancer 1 (5), 546-561, 2020
862020
Immune surveillance in clinical regression of preinvasive squamous cell lung cancer
A Pennycuick, VH Teixeira, K AbdulJabbar, SEA Raza, T Lund, ...
Cancer Discovery 10 (10), 1489-1499, 2020
742020
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters
M Linch, G Goh, C Hiley, Y Shanmugabavan, N McGranahan, A Rowan, ...
Annals of Oncology 28 (10), 2472-2480, 2017
672017
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