Lorin Crawford
Lorin Crawford
Senior Researcher, Microsoft Research
Verified email at microsoft.com - Homepage
Cited by
Cited by
Systematic mapping of BCL-2 gene dependencies in cancer reveals molecular determinants of BH3 mimetic sensitivity
RS Soderquist, L Crawford, E Liu, M Lu, A Agarwal, GR Anderson, KH Lin, ...
Nature communications 9 (1), 1-13, 2018
Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits
L Crawford, P Zeng, S Mukherjee, X Zhou
PLoS genetics 13 (7), e1006869, 2017
A landscape of therapeutic cooperativity in KRAS mutant cancers reveals principles for controlling tumor evolution
GR Anderson, PS Winter, KH Lin, DP Nussbaum, M Cakir, EM Stein, ...
Cell reports 20 (4), 999-1015, 2017
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence
KR Singleton, L Crawford, E Tsui, HE Manchester, O Maertens, X Liu, ...
Cell reports 21 (10), 2796-2812, 2017
Predicting clinical outcomes in glioblastoma: an application of topological and functional data analysis
L Crawford, A Monod, AX Chen, S Mukherjee, R Rabadán
Journal of the American Statistical Association 115 (531), 1139-1150, 2020
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation
GR Anderson, SE Wardell, M Cakir, L Crawford, JC Leeds, DP Nussbaum, ...
Science translational medicine 8 (369), 369ra175-369ra175, 2016
Bayesian approximate kernel regression with variable selection
L Crawford, KC Wood, X Zhou, S Mukherjee
Journal of the American Statistical Association 113 (524), 1710-1721, 2018
Fast and flexible linear mixed models for genome-wide genetics
DE Runcie, L Crawford
PLoS genetics 15 (2), e1007978, 2019
Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer
KH Lin, JC Rutter, A Xie, B Pardieu, ET Winn, R Dal Bello, A Forget, ...
Nature genetics 52 (4), 408-417, 2020
Stem cells and extracellular vesicles: biological regulators of physiology and disease
T Borgovan, L Crawford, C Nwizu, P Quesenberry
American Journal of Physiology-Cell Physiology 317 (2), C155-C166, 2019
Variable prioritization in nonlinear black box methods: A genetic association case study
L Crawford, SR Flaxman, DE Runcie, M West
The annals of applied statistics 13 (2), 958, 2019
Tropical sufficient statistics for persistent homology
A Monod, S Kalisnik, JÁ Patino-Galindo, L Crawford
SIAM Journal on Applied Algebra and Geometry 3 (2), 337-371, 2019
Interpreting deep neural networks through variable importance
J Ish-Horowicz, D Udwin, S Flaxman, S Filippi, L Crawford
arXiv preprint arXiv:1901.09839, 2019
Accepted elasticity in local arithmetic congruence monoids
L Crawford, V Ponomarenko, J Steinberg, M Williams
Results in Mathematics 66 (1), 227-245, 2014
A statistical pipeline for identifying physical features that differentiate classes of 3d shapes
B Wang, T Sudijono, H Kirveslahti, T Gao, DM Boyer, S Mukherjee, ...
The Annals of Applied Statistics 15 (2), 638-661, 2021
Estimation of non-null SNP effect size distributions enables the detection of enriched genes underlying complex traits
W Cheng, S Ramachandran, L Crawford
PLoS genetics 16 (6), e1008855, 2020
MegaLMM: Mega-scale linear mixed models for genomic predictions with thousands of traits
DE Runcie, J Qu, H Cheng, L Crawford
Genome biology 22 (1), 1-25, 2021
Natural variation in the regulation of neurodevelopmental genes modifies flight performance in Drosophila
AN Spierer, JA Mossman, SP Smith, L Crawford, S Ramachandran, ...
PLoS Genetics 17 (3), e1008887, 2021
The tumor microenvironment drives transcriptional phenotypes and their plasticity in metastatic pancreatic cancer
S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, RL Kalekar, ...
bioRxiv, 2020.08. 25.256214, 2021
Transcriptional subtype-specific microenvironmental crosstalk and tumor cell plasticity in metastatic pancreatic cancer
S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, RL Kalekar, ...
BioRxiv, 2020
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