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Jonatan Leffler
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Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease
J Leffler, M Martin, B Gullstrand, H Tydén, C Lood, L Truedsson, ...
The Journal of Immunology 188 (7), 3522-3531, 2012
5452012
The complement system in systemic lupus erythematosus: an update
J Leffler, AA Bengtsson, AM Blom
Annals of the rheumatic diseases 73 (9), 1601-1606, 2014
3002014
Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus
J Leffler, B Gullstrand, A Jönsen, JÅ Nilsson, M Martin, AM Blom, ...
Arthritis research & therapy 15, 1-9, 2013
1382013
Annexin A2 and A5 serve as new ligands for C1q on apoptotic cells
M Martin, J Leffler, AM Blom
Journal of Biological Chemistry 287 (40), 33733-33744, 2012
1262012
Factor H uptake regulates intracellular C3 activation during apoptosis and decreases the inflammatory potential of nucleosomes
M Martin, J Leffler, KI Smoląg, J Mytych, A Björk, LD Chaves, JJ Alexander, ...
Cell Death & Differentiation 23 (5), 903-911, 2016
962016
Degradation of neutrophil extracellular traps is decreased in patients with antiphospholipid syndrome
J Leffler, L Stojanovich, Y Shoenfeld, G Bogdanovic, R Hesselstrand, ...
Clin Exp Rheumatol 32 (1), 66-70, 2014
912014
Annexin-II, DNA, and histones serve as factor H ligands on the surface of apoptotic cells
J Leffler, AP Herbert, E Norström, CQ Schmidt, PN Barlow, AM Blom, ...
Journal of biological chemistry 285 (6), 3766-3776, 2010
852010
A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources
J Leffler, K Ciacma, B Gullstrand, AA Bengtsson, M Martin, AM Blom
Arthritis Research & Therapy 17, 1-10, 2015
522015
Immunological processes driving IgE sensitisation and disease development in males and females
J Leffler, PA Stumbles, DH Strickland
International Journal of Molecular Sciences 19 (6), 1554, 2018
462018
Plasma C4d as marker for lupus nephritis in systemic lupus erythematosus
M Martin, KI Smoląg, A Björk, B Gullstrand, M Okrój, J Leffler, A Jönsen, ...
Arthritis research & therapy 19, 1-9, 2017
462017
Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis
S Trend, J Leffler, AP Jones, L Cha, S Gorman, DA Brown, SN Breit, ...
Scientific Reports 11 (1), 5244, 2021
442021
Factor H autoantibodies in patients with antiphospholipid syndrome and thrombosis
AF Zadura, AA Memon, L Stojanovich, C Perricone, F Conti, G Valesini, ...
The Journal of rheumatology 42 (10), 1786-1793, 2015
352015
Protection against maternal infection-associated fetal growth restriction: proof-of-concept with a microbial-derived immunomodulator
NM Scott, JF Lauzon-Joset, AC Jones, KT Mincham, NM Troy, J Leffler, ...
Mucosal immunology 10 (3), 789-801, 2017
332017
Transplacental immune modulation with a bacterial-derived agent protects against allergic airway inflammation
KT Mincham, NM Scott, JF Lauzon-Joset, J Leffler, AN Larcombe, ...
The Journal of clinical investigation 128 (11), 4856-4869, 2018
302018
Decreased neutrophil extracellular trap degradation in Shiga toxin-associated haemolytic uraemic syndrome
J Leffler, Z Prohászka, B Mikes, G Sinkovits, K Ciacma, P Farkas, M Réti, ...
Journal of innate immunity 9 (1), 12-21, 2017
302017
Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school‐aged children
J Leffler, JF Read, AC Jones, D Mok, EM Hollams, IA Laing, PN Le Souef, ...
Pediatric Allergy and Immunology 30 (6), 646-653, 2019
222019
Oestrogen amplifies pre‐existing atopy‐associated Th2 bias in an experimental asthma model
JF Lauzon‐Joset, KT Mincham, AP Abad, BP Short, PG Holt, ...
Clinical & Experimental Allergy 50 (3), 391-400, 2020
182020
Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbations
J Leffler, AC Jones, EM Hollams, F Prastanti, PN Le Souëf, PG Holt, ...
Journal of Allergy and Clinical Immunology 142 (5), 1639-1641. e5, 2018
172018
Narrowband UVB phototherapy reduces TNF production by B‐cell subsets stimulated via TLR7 from individuals with early multiple sclerosis
S Trend, J Leffler, MN Cooper, SN Byrne, AG Kermode, MA French, ...
Clinical & Translational Immunology 9 (10), e1197, 2020
122020
Sex-specific environmental impacts on initiation and progression of multiple sclerosis
J Leffler, S Trend, S Gorman, PH Hart
Frontiers in Neurology 13, 835162, 2022
112022
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