Kalliopi Tsafou
Kalliopi Tsafou
Data Sciences & Quantitative Biology, AstraZeneca
Bekræftet mail på astrazeneca.com
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STRING v10: protein–protein interaction networks, integrated over the tree of life
D Szklarczyk, A Franceschini, S Wyder, K Forslund, D Heller, ...
Nucleic acids research 43 (D1), D447-D452, 2015
75132015
DISEASES: Text mining and data integration of disease–gene associations
S Pletscher-Frankild, A Pallejà, K Tsafou, JX Binder, LJ Jensen
Methods 74, 83-89, 2015
3912015
COMPARTMENTS: unification and visualization of protein subcellular localization evidence
JX Binder, S Pletscher-Frankild, K Tsafou, C Stolte, SI O’Donoghue, ...
Database 2014, 2014
3592014
Comprehensive comparison of large-scale tissue expression datasets
A Santos, K Tsafou, C Stolte, S Pletscher-Frankild, SI O’Donoghue, ...
PeerJ 3, e1054, 2015
802015
Phosphoproteomics of primary cells reveals druggable kinase signatures in ovarian cancer
C Francavilla, M Lupia, K Tsafou, A Villa, K Kowalczyk, ...
Cell reports 18 (13), 3242-3256, 2017
612017
Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation
KB Emdal, AK Pedersen, DB Bekker-Jensen, KP Tsafou, H Horn, ...
Science signaling 8 (374), ra40-ra40, 2015
592015
Targeting intrinsically disordered transcription factors: changing the paradigm
K Tsafou, PB Tiwari, JD Forman-Kay, SJ Metallo, JA Toretsky
Journal of molecular biology 430 (16), 2321-2341, 2018
572018
The second European interdisciplinary Ewing sarcoma research summit–A joint effort to deconstructing the multiple layers of a complex disease
H Kovar, J Amatruda, E Brunet, S Burdach, F Cidre-Aranaz, E De Alava, ...
Oncotarget 7 (8), 8613, 2016
472016
Reconstruction of the experimentally supported human protein interactome: what can we learn?
MI Klapa, K Tsafou, E Theodoridis, A Tsakalidis, NK Moschonas
BMC systems biology 7 (1), 1-14, 2013
282013
Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter
B Radic-Sarikas, M Halasz, KVM Huber, GE Winter, KP Tsafou, ...
Scientific reports 7 (1), 1-8, 2017
202017
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
R Pourhaghighi, PEA Ash, S Phanse, F Goebels, LZM Hu, S Chen, ...
Cell systems 10 (4), 333-350. e14, 2020
142020
Combinatorial drug screening identifies Ewing sarcoma–specific sensitivities
B Radic-Sarikas, KP Tsafou, KB Emdal, T Papamarkou, KVM Huber, ...
Molecular cancer therapeutics 16 (1), 88-101, 2017
112017
Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers
K Tsafou, AM Katschnig, B Radic-Sarikas, CN Mutz, K Iljin, R Schwentner, ...
Oncotarget 9 (57), 31018, 2018
82018
Human brain organoids reveal accelerated development of cortical neuron classes as a shared feature of autism risk genes
B Paulsen, S Velasco, AJ Kedaigle, M Pigoni, G Quadrato, A Deo, ...
bioRxiv, 2020
22020
PICKLE_DB: Developing a knowledge base for the human protein interactome
K Tsafou, E Theodoridis, C Makris, MI Klapa, A Tsakalidis, NK Moschonas
Fostering Systems and Synthetic Biology in Southern Europe, 5th meeting of …, 2009
12009
Combining Proteomics With Genetics to Elucidate the Molecular Mechanisms Underlying Posttraumatic Stress Disorder in Human Neurons
K Eggan, G Pintacuda, K Tsafou, YH Hsu, J Martin, N Fornelos, ...
Biological Psychiatry 89 (9), S11, 2021
2021
Interaction studies of risk proteins in human induced neurons reveal convergent biology and novel mechanisms underlying autism spectrum disorders
G Pintacuda, YHH Hsu, K Tsafou, KW Li, JM Martin, J Riseman, ...
medRxiv, 2021
2021
Using brain cell-type-specific protein interactomes to interpret genetic data in schizophrenia
YHH Hsu, E Nacu, R Liu, A Kim, K Tsafou, N Petrossian, W Crotty, JM Suh, ...
medRxiv, 2021
2021
Using protein interaction networks to identify cancer dependencies from tumor genome data
H Horn, C Fagre, A Gupta, K Tsafou, N Fornelos, JT Neal, K Lage
bioRxiv, 2020
2020
Integrative Systems Biology
K Tsafou, LJ Jensen
Academic Press, 2016
2016
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Artikler 1–20