| Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway TW Kensler, N Wakabayashi, S Biswal Annu. Rev. Pharmacol. Toxicol. 47, 89-116, 2007 | 3820 | 2007 |
| Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray RK Thimmulappa, KH Mai, S Srisuma, TW Kensler, M Yamamoto, ... Cancer research 62 (18), 5196-5203, 2002 | 1505 | 2002 |
| Dysfunctional KEAP1–NRF2 interaction in non-small-cell lung cancer A Singh, V Misra, RK Thimmulappa, H Lee, S Ames, MO Hoque, ... PLoS medicine 3 (10), e420, 2006 | 1203 | 2006 |
| Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice T Rangasamy, CY Cho, RK Thimmulappa, L Zhen, SS Srisuma, ... The Journal of clinical investigation 114 (9), 1248-1259, 2004 | 1151 | 2004 |
| Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis RK Thimmulappa, H Lee, T Rangasamy, SP Reddy, M Yamamoto, ... The Journal of clinical investigation 116 (4), 984-995, 2016 | 1129 | 2016 |
| Multiple-laboratory comparison of microarray platforms RA Irizarry, D Warren, F Spencer, IF Kim, S Biswal, BC Frank, ... Nature methods 2 (5), 345-350, 2005 | 1059 | 2005 |
| Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis D Malhotra, E Portales-Casamar, A Singh, S Srivastava, D Arenillas, ... Nucleic acids research 38 (17), 5718-5734, 2010 | 837 | 2010 |
| Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice T Rangasamy, J Guo, WA Mitzner, J Roman, A Singh, AD Fryer, ... The Journal of experimental medicine 202 (1), 47-59, 2005 | 679 | 2005 |
| The molecular effects of acrolein JP Kehrer, SS Biswal Toxicological Sciences 57 (1), 6-15, 2000 | 633 | 2000 |
| Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress CJ Harvey, RK Thimmulappa, A Singh, DJ Blake, G Ling, N Wakabayashi, ... Free Radical Biology and Medicine 46 (4), 443-453, 2009 | 515 | 2009 |
| Nrf2 and Keap1 abnormalities in non–small cell lung carcinoma and association with clinicopathologic features LM Solis, C Behrens, W Dong, M Suraokar, NC Ozburn, CA Moran, ... Clinical cancer research 16 (14), 3743-3753, 2010 | 501 | 2010 |
| Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model TE Sussan, S Gajghate, RK Thimmulappa, J Ma, JH Kim, K Sudini, ... PloS one 10 (2), e0116861, 2015 | 464 | 2015 |
| Environmental determinants of cardiovascular disease: lessons learned from air pollution SG Al-Kindi, RD Brook, S Biswal, S Rajagopalan Nature Reviews Cardiology 17 (10), 656-672, 2020 | 440 | 2020 |
| Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors A Singh, S Venkannagari, KH Oh, YQ Zhang, JM Rohde, L Liu, ... ACS chemical biology 11 (11), 3214-3225, 2016 | 437 | 2016 |
| RNAi-mediated silencing of nuclear factor erythroid-2–related factor 2 gene expression in non–small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy A Singh, S Boldin-Adamsky, RK Thimmulappa, SK Rath, H Ashush, ... Cancer research 68 (19), 7975-7984, 2008 | 433 | 2008 |
| Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth P Zhang, A Singh, S Yegnasubramanian, D Esopi, P Kombairaju, ... Molecular cancer therapeutics 9 (2), 336-346, 2010 | 417 | 2010 |
| Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide RK Thimmulappa, C Scollick, K Traore, M Yates, MA Trush, KT Liby, ... Biochemical and biophysical research communications 351 (4), 883-889, 2006 | 410 | 2006 |
| Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice TE Sussan, T Rangasamy, DJ Blake, D Malhotra, H El-Haddad, D Bedja, ... Proceedings of the National Academy of Sciences 106 (1), 250-255, 2009 | 379 | 2009 |
| NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis S Shin, N Wakabayashi, V Misra, S Biswal, GH Lee, ES Agoston, ... Molecular and cellular biology 27 (20), 7188-7197, 2007 | 363 | 2007 |
| Targeting Nrf2 signaling improves bacterial clearance by alveolar macrophages in patients with COPD and in a mouse model CJ Harvey, RK Thimmulappa, S Sethi, X Kong, L Yarmus, RH Brown, ... Science translational medicine 3 (78), 78ra32-78ra32, 2011 | 352 | 2011 |
Thomas KenslerFred Hutchinson Cancer Research CenterVerificeret mail på fredhutch.org
