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Vidya Velagapudi, Ph.D
Vidya Velagapudi, Ph.D
Director, AstraZeneca
Verificeret mail på astrazeneca.com
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År
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
M López, L Varela, MJ Vázquez, S Rodríguez-Cuenca, CR González, ...
Nature medicine 16 (9), 1001-1008, 2010
7492010
The gut microbiota modulates host energy and lipid metabolism in mice [S]
VR Velagapudi, R Hezaveh, CS Reigstad, P Gopalacharyulu, L Yetukuri, ...
Journal of lipid research 51 (5), 1101-1112, 2010
6622010
Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3
SA Khan NA, Auranen M, Paetau I, Pirinen E, Euro L, Forsström S, Pasila L ...
EMBO Mol Med 6 (6), 721-31, 2014
4132014
Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice
X Prieur, CYL Mok, VR Velagapudi, V Núñez, L Fuentes, D Montaner, ...
Diabetes 60 (3), 797-809, 2011
4132011
Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity
M Kolak, J Westerbacka, VR Velagapudi, D Wagsater, L Yetukuri, ...
Diabetes 56 (8), 1960-1968, 2007
3772007
Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity
J Prawitt, M Abdelkarim, JHM Stroeve, I Popescu, H Duez, VR Velagapudi, ...
Diabetes 60 (7), 1861-1871, 2011
3462011
mTORC1 regulates mitochondrial integrated stress response and mitochondrial myopathy progression
NA Khan, J Nikkanen, S Yatsuga, C Jackson, L Wang, S Pradhan, ...
Cell metabolism 26 (2), 419-428. e5, 2017
3332017
Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans
KH Pietiläinen, T Rog, T Seppänen-Laakso, S Virtue, P Gopalacharyulu, ...
PLoS biology 9 (6), e1000623, 2011
2722011
Mitochondrial DNA replication defects disturb cellular dNTP pools and remodel one-carbon metabolism
J Nikkanen, S Forsström, L Euro, I Paetau, RA Kohnz, L Wang, D Chilov, ...
Cell metabolism 23 (4), 635-648, 2016
2562016
Host-microbe co-metabolism dictates cancer drug efficacy in C. elegans
TA Scott, LM Quintaneiro, P Norvaisas, PP Lui, MP Wilson, KY Leung, ...
Cell 169 (3), 442-456. e18, 2017
2362017
Niacin cures systemic NAD+ deficiency and improves muscle performance in adult-onset mitochondrial myopathy
E Pirinen, M Auranen, NA Khan, V Brilhante, N Urho, A Pessia, ...
Cell metabolism 31 (6), 1078-1090. e5, 2020
2122020
Serum saturated fatty acids containing triacylglycerols are better markers of insulin resistance than total serum triacylglycerol concentrations
A Kotronen, VR Velagapudi, L Yetukuri, J Westerbacka, R Bergholm, ...
Diabetologia 52, 684-690, 2009
2072009
Hypothalamic AMPK-ER stress-JNK1 axis mediates the central actions of thyroid hormones on energy balance
N Martínez-Sánchez, P Seoane-Collazo, C Contreras, L Varela, ...
Cell metabolism 26 (1), 212-229. e12, 2017
1992017
Metabolomic profiling of extracellular vesicles and alternative normalization methods reveal enriched metabolites and strategies to study prostate cancer-related changes
M Puhka, M Takatalo, ME Nordberg, S Valkonen, J Nandania, M Aatonen, ...
Theranostics 7 (16), 3824, 2017
1952017
Faecal and serum metabolomics in paediatric inflammatory bowel disease
KL Kolho, A Pessia, T Jaakkola, WM de Vos, V Velagapudi
Journal of Crohn's and Colitis 11 (3), 321-334, 2017
1912017
Fibroblast growth factor 21 drives dynamics of local and systemic stress responses in mitochondrial myopathy with mtDNA deletions
S Forsström, CB Jackson, CJ Carroll, M Kuronen, E Pirinen, S Pradhan, ...
Cell metabolism 30 (6), 1040-1054. e7, 2019
1812019
Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics
SU Vorrink, S Ullah, S Schmidt, J Nandania, V Velagapudi, O Beck, ...
The FASEB Journal 31 (6), 2696, 2017
1502017
The pentose phosphate pathway regulates the circadian clock
G Rey, UK Valekunja, KA Feeney, L Wulund, NB Milev, A Stangherlin, ...
Cell metabolism 24 (3), 462-473, 2016
1492016
Vitamin B12–dependent taurine synthesis regulates growth and bone mass
P Roman-Garcia, I Quiros-Gonzalez, L Mottram, L Lieben, K Sharan, ...
The Journal of clinical investigation 124 (7), 2988-3002, 2014
1472014
Preanalytical processing and biobanking procedures of biological samples for metabolomics research: A white paper, community perspective (for “Precision medicine and …
JA Kirwan, L Brennan, D Broadhurst, O Fiehn, M Cascante, WB Dunn, ...
Clinical Chemistry 64 (8), 1158-1182, 2018
1302018
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