Lauren F. Sestito
Lauren F. Sestito
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Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy
DM Francis, MP Manspeaker, A Schudel, LF Sestito, MJ O’Melia, ...
Science translational medicine 12 (563), eaay3575, 2020
Thermosensitive hydrogel releasing nitric oxide donor and anti-CTLA-4 micelles for anti-tumor immunotherapy
J Kim, DM Francis, LF Sestito, PA Archer, MP Manspeaker, MJ O’Melia, ...
Nature Communications 13 (1), 1479, 2022
Poly (cyclodextrin)‐Polydrug Nanocomplexes as Synthetic Oncolytic Virus for Locoregional Melanoma Chemoimmunotherapy
J Kim, LF Sestito, S Im, WJ Kim, SN Thomas
Advanced functional materials 30 (16), 1908788, 2020
Lymph-directed nitric oxide increases immune cell access to lymph-borne nanoscale solutes
LF Sestito, SN Thomas
Biomaterials 265, 120411, 2021
Drug-eluting immune checkpoint blockade antibody-nanoparticle conjugate enhances locoregional and systemic combination cancer immunotherapy through T lymphocyte targeting
DM Francis, MP Manspeaker, PA Archer, LF Sestito, AJ Heiler, A Schudel, ...
Biomaterials 279, 121184, 2021
Biomaterials for modulating lymphatic function in immunoengineering
LF Sestito, SN Thomas
ACS Pharmacology & Translational Science 2 (5), 293-310, 2019
S-nitrosated poly (propylene sulfide) nanoparticles for enhanced nitric oxide delivery to lymphatic tissues
A Schudel, LF Sestito, SN Thomas
Journal of biomedical materials research. Part A 106 (6), 1463, 2018
The Kinetics of Lymphatic Dysfunction and Leukocyte Expansion in the Draining Lymph Node during LTB4 Antagonism in a Mouse Model of Lymphedema
MT Cribb, LF Sestito, SG Rockson, MR Nicolls, SN Thomas, JB Dixon
International Journal of Molecular Sciences 22 (9), 4455, 2021
Winner of the society for biomaterials young investigator award for the annual meeting of the society for biomaterials, April 11–14, 2018, Atlanta, GA: S‐nitrosated poly …
A Schudel, LF Sestito, SN Thomas
Journal of Biomedical Materials Research Part A 106 (6), 1463-1475, 2018
Quantitation of lymphatic transport mechanism and barrier influences on lymph node-resident leukocyte access to lymph-borne macromolecules and drug delivery systems
PA Archer, LF Sestito, MP Manspeaker, MJ O’Melia, NA Rohner, ...
Drug delivery and translational research 11 (6), 2328-2343, 2021
Adhesion analysis via a tumor vasculature-like microfluidic device identifies CD8+ T cells with enhanced tumor homing to improve cell therapy
CP Camargo, AK Muhuri, Y Alapan, LF Sestito, M Khosla, ...
Cell reports 42 (3), 2023
Lymphatic-draining nanoparticles deliver Bay K8644 payload to lymphatic vessels and enhance their pumping function
LF Sestito, KHT To, MT Cribb, PA Archer, SN Thomas, JB Dixon
Science Advances 9 (8), eabq0435, 2023
Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy. Sci Transl Med 2020; 12
DM Francis, MP Manspeaker, A Schudel, LF Sestito, MJ O'Melia, ...
Engineered biomaterials for drug delivery and therapeutic modulation in lymphatic tissues
LF Sestito
Georgia Institute of Technology, 2021
Development of a Classroom-Feasible Protocol for Carbon Dot Synthesis & Characterization
P Krout, L Sestito
Development of a Liposomal Drug Delivery System for the Treatment of Lymphatic Filariasis
ES Annis, L Sestito
Synthesis and Characterization of Sodium Alginate Hydrogels for Lymphatic Drug Delivery
KP Frank, L Sestito
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