A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease T Ramesh, AN Lyon, RH Pineda, C Wang, PML Janssen, BD Canan, ... Disease models & mechanisms 3 (9-10), 652-662, 2010 | 170 | 2010 |
Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice JA Rafael-Fortney, NS Chimanji, KE Schill, CD Martin, JD Murray, ... Circulation 124 (5), 582-588, 2011 | 162 | 2011 |
In vivo genome editing restores dystrophin expression and cardiac function in dystrophic mice M El Refaey, L Xu, Y Gao, BD Canan, TMA Adesanya, SC Warner, ... Circulation research 121 (8), 923-929, 2017 | 146 | 2017 |
Micro-dystrophin and follistatin co-delivery restores muscle function in aged DMD model LR Rodino-Klapac, PML Janssen, KM Shontz, B Canan, CL Montgomery, ... Human molecular genetics 22 (24), 4929-4937, 2013 | 91 | 2013 |
IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism N Bakkar, K Ladner, BD Canan, S Liyanarachchi, NC Bal, M Pant, ... Journal of Cell Biology 196 (4), 497-511, 2012 | 89 | 2012 |
Peptide-based inhibition of NF-κB rescues diaphragm muscle contractile dysfunction in a murine model of Duchenne muscular dystrophy JM Peterson, W Kline, BD Canan, DJ Ricca, B Kaspar, DA Delfín, ... Molecular medicine 17, 508-515, 2011 | 83 | 2011 |
mdx5cv mice manifest more severe muscle dysfunction and diaphragm force deficits than do mdx mice N Beastrom, H Lu, A Macke, BD Canan, EK Johnson, CM Penton, ... The American journal of pathology 179 (5), 2464-2474, 2011 | 68 | 2011 |
The Frank-Starling mechanism involves deceleration of cross-bridge kinetics and is preserved in failing human right ventricular myocardium N Milani-Nejad, BD Canan, MT Elnakish, JP Davis, JH Chung, ... American Journal of Physiology-Heart and Circulatory Physiology 309 (12 …, 2015 | 43 | 2015 |
NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model JM Peterson, DJ Wang, V Shettigar, SR Roof, BD Canan, N Bakkar, ... Nature communications 9 (1), 3431, 2018 | 37 | 2018 |
Etiology-dependent impairment of relaxation kinetics in right ventricular end-stage failing human myocardium JH Chung, BL Martin, BD Canan, MT Elnakish, N Milani-Nejad, NS Saad, ... Journal of molecular and cellular cardiology 121, 81-93, 2018 | 32 | 2018 |
Human myocardium has a robust α1A-subtype adrenergic receptor inotropic response PML Janssen, BD Canan, A Kilic, BA Whitson, AJ Baker Journal of cardiovascular pharmacology 72 (3), 136-142, 2018 | 29 | 2018 |
Defining the molecular signatures of human right heart failure JL Williams, O Cavus, EC Loccoh, S Adelman, JC Daugherty, SA Smith, ... Life sciences 196, 118-126, 2018 | 24 | 2018 |
Claudin-5 levels are reduced from multiple cell types in human failing hearts and are associated with mislocalization of ephrin-B1 SA Swager, DA Delfín, N Rastogi, H Wang, BD Canan, VV Fedorov, ... Cardiovascular Pathology 24 (3), 160-167, 2015 | 24 | 2015 |
Sustaining cardiac claudin-5 levels prevents functional hallmarks of cardiomyopathy in a muscular dystrophy mouse model DA Delfín, Y Xu, KE Schill, TA Mays, BD Canan, KE Zang, JA Barnum, ... Molecular Therapy 20 (7), 1378-1383, 2012 | 24 | 2012 |
Using computer‐extracted data from electronic health records to measure the quality of adolescent well‐care W Gardner, S Morton, SC Byron, A Tinoco, BD Canan, K Leonhart, ... Health services research 49 (4), 1226-1248, 2014 | 22 | 2014 |
Altered protein levels in the isolated extracellular matrix of failing human hearts with dilated cardiomyopathy JL DeAguero, EN McKown, L Zhang, J Keirsey, EG Fischer, VG Samedi, ... Cardiovascular Pathology 26, 12-20, 2017 | 20 | 2017 |
Impact of etiology on force and kinetics of left ventricular end-stage failing human myocardium MA Mashali, NS Saad, BD Canan, MT Elnakish, N Milani-Nejad, ... Journal of molecular and cellular cardiology 156, 7-19, 2021 | 18 | 2021 |
Effects of zacopride, a moderate IK1 channel agonist, on triggered arrhythmia and contractility in human ventricular myocardium MT Elnakish, BD Canan, A Kilic, PJ Mohler, PML Janssen Pharmacological research 115, 309-318, 2017 | 18 | 2017 |
Association of genetic polymorphisms in the beta-1 adrenergic receptor with recovery of left ventricular ejection fraction in patients with heart failure JA Luzum, JD English, US Ahmad, JW Sun, BD Canan, W Sadee, ... Journal of cardiovascular translational research 12, 280-289, 2019 | 15 | 2019 |
Force‐frequency relationship and early relaxation kinetics are preserved upon sarcoplasmic blockade in human myocardium JH Chung, BD Canan, BA Whitson, A Kilic, PML Janssen Physiological reports 6 (20), e13898, 2018 | 15 | 2018 |