| Next generation 3D pharmacophore modeling D Schaller, D Šribar, T Noonan, L Deng, TN Nguyen, S Pach, D Machalz, ... Wiley Interdisciplinary Reviews: Computational Molecular Science 10 (4), e1468, 2020 | 169 | 2020 |
| Efficient substrate screening and inhibitor testing of human CYP4Z1 using permeabilized recombinant fission yeast Q Yan, D Machalz, A Zoellner, EJ Sorensen, G Wolber, M Bureik Biochemical pharmacology 146, 174-187, 2017 | 47 | 2017 |
| Functional characterization and mechanistic modeling of the human cytochrome P450 enzyme CYP4A22 P Durairaj, L Fan, D Machalz, G Wolber, M Bureik FEBS letters 593 (16), 2214-2225, 2019 | 25 | 2019 |
| Structural insights into understudied human cytochrome P450 enzymes D Machalz, S Pach, M Bermudez, M Bureik, G Wolber Drug discovery today 26 (10), 2456-2464, 2021 | 22 | 2021 |
| Importance of asparagine-381 and arginine-487 for substrate recognition in CYP4Z1 W Du, D Machalz, Q Yan, EJ Sorensen, G Wolber, M Bureik Biochemical Pharmacology 174, 113850, 2020 | 19 | 2020 |
| Functional expression of all human sulfotransferases in fission yeast, assay development, and structural models for isoforms SULT4A1 and SULT6B1 Y Sun, D Machalz, G Wolber, MK Parr, M Bureik Biomolecules 10 (11), 1517, 2020 | 17 | 2020 |
| Fine-mapping of the substrate specificity of human steroid 21-hydroxylase (CYP21A2) A Stoll, S Loke, JF Joseph, D Machalz, X de la Torre, F Botre, G Wolber, ... The Journal of Steroid Biochemistry and Molecular Biology 194, 105446, 2019 | 17 | 2019 |
| Comparison of the three SARMs RAD-140, GLPG0492 and GSK-2881078 in two different in vitro bioassays, and in an in silico androgen receptor binding assay O Zierau, A Kolodziejczyk, G Vollmer, D Machalz, G Wolber, D Thieme, ... The Journal of steroid biochemistry and molecular biology 189, 81-86, 2019 | 15 | 2019 |
| Discovery of a novel potent cytochrome P450 CYP4Z1 inhibitor D Machalz, H Li, W Du, S Sharma, S Liu, M Bureik, G Wolber European Journal of Medicinal Chemistry 215, 113255, 2021 | 14 | 2021 |
| New proluciferin substrates for human CYP4 family enzymes J Liu, D Machalz, G Wolber, EJ Sorensen, M Bureik Applied Biochemistry and Biotechnology 193, 218-237, 2021 | 13 | 2021 |
| A common polymorphic variant of UGT 1A5 displays increased activity due to optimized cofactor binding F Yang, D Machalz, S Wang, Z Li, G Wolber, M Bureik FEBS letters 592 (11), 1837-1846, 2018 | 13 | 2018 |
| A benzoxazole derivative as an inhibitor of anaerobic choline metabolism by human gut microbiota MT Gabr, D Machalz, S Pach, G Wolber RSC Medicinal Chemistry 11 (12), 1402-1412, 2020 | 8 | 2020 |
| Androgen-and estrogen-receptor mediated activities of 4-hydroxytestosterone, 4-hydroxyandrostenedione and their human metabolites in yeast based assays AM Keiler, O Zierau, S Wolf, P Diel, W Schänzer, G Vollmer, D Machalz, ... Toxicology Letters 292, 39-45, 2018 | 8 | 2018 |
| Metabolism of the antipsychotic drug olanzapine by CYP3A43 J Zhao, D Machalz, S Liu, CA Wolf, G Wolber, MK Parr, M Bureik Xenobiotica 52 (4), 413-425, 2022 | 4 | 2022 |
| Corticosteroid biosynthesis revisited: No direct hydroxylation of pregnenolone by steroid 21-hydroxylase S Loke, A Stoll, D Machalz, F Botrè, G Wolber, M Bureik, MK Parr Frontiers in Endocrinology 12, 633785, 2021 | 2 | 2021 |
| A convenient test system for the identification of CYP4V2 inhibitors S Sharma, S Liu, P Durairaj, D Machalz, G Wolber, M Bureik Molecular Vision 27, 601, 2021 | 1 | 2021 |
| Deorphanizing Human Cytochrome P450 Enzymes CYP4A22 and CYP4Z1 through Mechanistic in silico modeling D Machalz | | 2022 |
| Corticosteroid Biosynthesis Revisited: Substrate Specificity of Steroid 21‐Hydroxylase S Loke, A Stoll, JF Joseph, D Machalz, X de la Torre, F Botre, G Wolber, ... The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
Gerhard WolberProfessor for Pharmaceutical ChemistryVerified email at fu-berlin.de
