Neurotoxic reactive astrocytes are induced by activated microglia SA Liddelow, KA Guttenplan, LE Clarke, FC Bennett, CJ Bohlen, ... Nature 541 (7638), 481-487, 2017 | 6664 | 2017 |
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex Y Zhang, K Chen, SA Sloan, ML Bennett, AR Scholze, S O'Keeffe, ... Journal of neuroscience 34 (36), 11929-11947, 2014 | 4890 | 2014 |
Reactive astrocytes: production, function, and therapeutic potential SA Liddelow, BA Barres Immunity 46 (6), 957-967, 2017 | 2123 | 2017 |
New tools for studying microglia in the mouse and human CNS ML Bennett, FC Bennett, SA Liddelow, B Ajami, JL Zamanian, NB Fernhoff, ... Proceedings of the National Academy of Sciences 113 (12), E1738-E1746, 2016 | 1794 | 2016 |
Reactive astrocyte nomenclature, definitions, and future directions C Escartin, E Galea, A Lakatos, JP O’Callaghan, GC Petzold, ... Nature neuroscience 24 (3), 312-325, 2021 | 1642 | 2021 |
Normal aging induces A1-like astrocyte reactivity LE Clarke, SA Liddelow, C Chakraborty, AE Münch, M Heiman, BA Barres Proceedings of the National Academy of Sciences 115 (8), E1896-E1905, 2018 | 1170 | 2018 |
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy Y Shi, K Yamada, SA Liddelow, ST Smith, L Zhao, W Luo, RM Tsai, ... Nature 549 (7673), 523-527, 2017 | 1052 | 2017 |
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease SP Yun, TI Kam, N Panicker, SM Kim, Y Oh, JS Park, SH Kwon, YJ Park, ... Nature medicine 24 (7), 931-938, 2018 | 932 | 2018 |
Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development ID Vainchtein, G Chin, FS Cho, KW Kelley, JG Miller, EC Chien, ... Science 359 (6381), 1269-1273, 2018 | 560 | 2018 |
Barrier mechanisms in the developing brain NR Saunders, SA Liddelow, KM Dziegielewska Frontiers in pharmacology 3, 46, 2012 | 542 | 2012 |
Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration AU Joshi, PS Minhas, SA Liddelow, B Haileselassie, KI Andreasson, ... Nature neuroscience 22 (10), 1635-1648, 2019 | 459 | 2019 |
Neuroinflammatory astrocyte subtypes in the mouse brain P Hasel, IVL Rose, JS Sadick, RD Kim, SA Liddelow Nature neuroscience 24 (10), 1475-1487, 2021 | 408 | 2021 |
Neurotoxic reactive astrocytes induce cell death via saturated lipids KA Guttenplan, MK Weigel, P Prakash, PR Wijewardhane, P Hasel, ... Nature 599 (7883), 102-107, 2021 | 396 | 2021 |
Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation A Fernández-Castañeda, P Lu, AC Geraghty, E Song, MH Lee, J Wood, ... Cell 185 (14), 2452-2468. e16, 2022 | 360 | 2022 |
Methotrexate chemotherapy induces persistent tri-glial dysregulation that underlies chemotherapy-related cognitive impairment EM Gibson, S Nagaraja, A Ocampo, LT Tam, LS Wood, PN Pallegar, ... Cell 176 (1), 43-55. e13, 2019 | 287 | 2019 |
Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model KA Guttenplan, MK Weigel, DI Adler, J Couthouis, SA Liddelow, AD Gitler, ... Nature communications 11 (1), 3753, 2020 | 235 | 2020 |
Development of the choroid plexus and blood-CSF barrier SA Liddelow Frontiers in neuroscience 9, 32, 2015 | 230 | 2015 |
Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease JS Sadick, MR O’Dea, P Hasel, T Dykstra, A Faustin, SA Liddelow Neuron 110 (11), 1788-1805. e10, 2022 | 200 | 2022 |
Microglia and astrocytes in disease: dynamic duo or partners in crime? SA Liddelow, SE Marsh, B Stevens Trends in Immunology 41 (9), 820-835, 2020 | 196 | 2020 |
Neurotoxic reactive astrocytes drive neuronal death after retinal injury KA Guttenplan, BK Stafford, RN El-Danaf, DI Adler, AE Münch, MK Weigel, ... Cell reports 31 (12), 2020 | 186 | 2020 |