Correlated alterations in genome organization, histone methylation, and DNA–lamin A/C interactions in Hutchinson-Gilford progeria syndrome RP McCord, A Nazario-Toole, H Zhang, PS Chines, Y Zhan, MR Erdos, ... Genome research 23 (2), 260-269, 2013 | 345 | 2013 |
Chromatin structure dynamics during the mitosis-to-G1 phase transition H Zhang, DJ Emerson, TG Gilgenast, KR Titus, Y Lan, P Huang, D Zhang, ... Nature 576 (7785), 158-162, 2019 | 183 | 2019 |
Methylene blue alleviates nuclear and mitochondrial abnormalities in progeria ZM Xiong, JY Choi, K Wang, H Zhang, Z Tariq, DI Wu, E Ko, C LaDana, ... Aging cell 15 (2), 279-290, 2016 | 124 | 2016 |
A tissue engineered blood vessel model of Hutchinson-Gilford progeria syndrome using human iPSC-derived smooth muscle cells L Atchison, H Zhang, K Cao, GA Truskey Scientific reports 7 (1), 8168, 2017 | 107 | 2017 |
Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly (ADP-ribose) polymerase 1 H Zhang, ZM Xiong, K Cao Proceedings of the National Academy of Sciences 111 (22), E2261-E2270, 2014 | 102 | 2014 |
Mouse models of laminopathies H Zhang, JE Kieckhaefer, K Cao Aging cell 12 (1), 2-10, 2013 | 89 | 2013 |
Comprehensive map of age-associated splicing changes across human tissues and their contributions to age-associated diseases K Wang, D Wu, H Zhang, A Das, M Basu, J Malin, K Cao, S Hannenhalli Scientific reports 8 (1), 10929, 2018 | 64 | 2018 |
Lamin A and microtubules collaborate to maintain nuclear morphology Z Tariq, H Zhang, A Chia-Liu, Y Shen, Y Gete, ZM Xiong, C Tocheny, ... Nucleus 8 (4), 433-446, 2017 | 57 | 2017 |
Distinct properties and functions of CTCF revealed by a rapidly inducible degron system J Luan, G Xiang, PA Gómez-García, JM Tome, Z Zhang, MW Vermunt, ... Cell reports 34 (8), 2021 | 56 | 2021 |
BRD4 orchestrates genome folding to promote neural crest differentiation R Linares-Saldana, W Kim, NA Bolar, H Zhang, BA Koch-Bojalad, S Yoon, ... Nature genetics 53 (10), 1480-1492, 2021 | 50 | 2021 |
CTCF and transcription influence chromatin structure re-configuration after mitosis H Zhang, J Lam, D Zhang, Y Lan, MW Vermunt, CA Keller, B Giardine, ... Nature communications 12 (1), 5157, 2021 | 41 | 2021 |
Alteration of genome folding via contact domain boundary insertion D Zhang, P Huang, M Sharma, CA Keller, B Giardine, H Zhang, ... Nature genetics 52 (10), 1076-1087, 2020 | 38 | 2020 |
Loss of H3K9me3 correlates with ATM activation and histone H2AX phosphorylation deficiencies in Hutchinson-Gilford progeria syndrome H Zhang, L Sun, K Wang, D Wu, M Trappio, C Witting, K Cao PLoS One 11 (12), e0167454, 2016 | 37 | 2016 |
Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation D Wu, PA Yates, H Zhang, K Cao Nucleus 7 (6), 585-596, 2016 | 12 | 2016 |
CTCF blocks antisense transcription initiation at divergent promoters J Luan, MW Vermunt, CM Syrett, A Coté, JM Tome, H Zhang, A Huang, ... Nature structural & molecular biology 29 (11), 1136-1144, 2022 | 9 | 2022 |
CTCF blocks anti-sense transcription initiation at divergent gene promoters J Luan, CM Syrett, MW Vermunt, A Coté, JM Tome, H Zhang, A Huang, ... BioRxiv, 2021.10. 30.465508, 2021 | 6 | 2021 |
Mechanisms of genome instability in Hutchinson-Gilford progeria H Zhang, K Cao Frontiers in Biology 12, 49-62, 2017 | 1 | 2017 |